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ChemicalBook >> SIRT7 Polyclonal Antibody

SIRT7 Polyclonal Antibody

SIRT7 Polyclonal Antibody price.
1 prices
Selected condition:
Brand
  • Cayman Chemical
Package
  • 1ea
  • ManufacturerCayman Chemical
  • Product number13477
  • Product descriptionSIRT7 Polyclonal Antibody
  • Packaging1ea
  • Price$323
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 13477 SIRT7 Polyclonal Antibody 1ea $323 2024-03-01 Buy

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Description

SIRT7 is a member of a famiy of proteins called sirtuins (SIR2-like proteins) and are present in prokaryotes and eukaryotes. All SIR2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast, and mammalian sirtuins are able to metabolize NAD+ and several act as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated SIR2-mediated NAD+ metabolism and NAD+-activated SIR2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of SIR2 with NAD+ and the N-ε-acetyl-lysine groups of acetylated histone.