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ChemicalBook >> CAS DataBase List >> SKL 2001

SKL 2001

SKL 2001 price.
  • $34 - $1300
  • Product name: SKL 2001
  • CAS: 909089-13-0
  • MF: C14H14N4O3
  • MW: 286.29
  • EINECS:
  • MDL Number:MFCD14733081
  • Synonyms:SKL 2001;N-(3-(1H-imidazol-1-yl)propyl)-5-(furan-2-yl)isoxazole-3-carboxamide;CS-2771;SKL2001;SKL-2001;SKL 2001;SKL-2001;SKL 2001;5-(furan-2-yl)-N-[3-(1H-imidazol-1-yl)propyl]-1,2-oxazole-3-carboxamide;2001;SKL2001 free base
18 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number2007CW
  • Product description5-(Furan-2-yl)-N-(3-imidazol-1-ylpropyl)-1,2-oxazole-3-carboxamide
  • Packaging5mg
  • Price$152
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA660516
  • Product descriptionSKL2001 98+%
  • Packaging5mg
  • Price$34
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA660516
  • Product descriptionSKL2001 98+%
  • Packaging10mg
  • Price$48
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA660516
  • Product descriptionSKL2001 98+%
  • Packaging50mg
  • Price$115
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA660516
  • Product descriptionSKL2001 98+%
  • Packaging100mg
  • Price$184
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA660516
  • Product descriptionSKL2001 98+%
  • Packaging250mg
  • Price$227
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA660516
  • Product descriptionSKL2001 98+%
  • Packaging1g
  • Price$567
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number26334
  • Product descriptionSKL2001
  • Packaging5mg
  • Price$49
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number26334
  • Product descriptionSKL2001
  • Packaging10mg
  • Price$92
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number26334
  • Product descriptionSKL2001
  • Packaging25mg
  • Price$216
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number26334
  • Product descriptionSKL2001
  • Packaging100mg
  • Price$665
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0020797
  • Product descriptionSKL2001 99.54%
  • Packaging10mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0020797
  • Product descriptionSKL2001 99.54%
  • Packaging50mg
  • Price$290
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0020797
  • Product descriptionSKL2001 99.54%
  • Packaging100mg
  • Price$520
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0020797
  • Product descriptionSKL2001 99.54%
  • Packaging200mg
  • Price$820
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10888
  • Product descriptionSKL2001 >98%
  • Packaging100mg
  • Price$400
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2007CW 5-(Furan-2-yl)-N-(3-imidazol-1-ylpropyl)-1,2-oxazole-3-carboxamide 5mg $152 2021-12-16 Buy
Ambeed A660516 SKL2001 98+% 5mg $34 2021-12-16 Buy
Ambeed A660516 SKL2001 98+% 10mg $48 2021-12-16 Buy
Ambeed A660516 SKL2001 98+% 50mg $115 2021-12-16 Buy
Ambeed A660516 SKL2001 98+% 100mg $184 2021-12-16 Buy
Ambeed A660516 SKL2001 98+% 250mg $227 2021-12-16 Buy
Ambeed A660516 SKL2001 98+% 1g $567 2021-12-16 Buy
Cayman Chemical 26334 SKL2001 5mg $49 2024-03-01 Buy
Cayman Chemical 26334 SKL2001 10mg $92 2024-03-01 Buy
Cayman Chemical 26334 SKL2001 25mg $216 2024-03-01 Buy
Cayman Chemical 26334 SKL2001 100mg $665 2024-03-01 Buy
ChemScene CS-0020797 SKL2001 99.54% 10mg $70 2021-12-16 Buy
ChemScene CS-0020797 SKL2001 99.54% 50mg $290 2021-12-16 Buy
ChemScene CS-0020797 SKL2001 99.54% 100mg $520 2021-12-16 Buy
ChemScene CS-0020797 SKL2001 99.54% 200mg $820 2021-12-16 Buy
DC Chemicals DC10888 SKL2001 >98% 100mg $400 2021-12-16 Buy

Properties

Boiling point :595.7±50.0 °C(Predicted)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: 25 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
form :A crystalline solid
pka :13.36±0.46(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

SKL2001 is an activator of Wnt/β-catenin signaling. It increases β-catenin responsive transcription in a cell-based reporter assay in a concentration-dependent manner, increases β-catenin protein levels in HEK293 cells when used at concentrations of 10 and 30 μM, and disrupts the interaction between Axin and β-catenin. SKL2001 increases alkaline phosphatase (ALP) activity and mineralization in multipotent mesenchymal ST2 cells in a concentration-dependent manner, indicating increased osteoblastogenesis. SKL2001 (40 μM) reduces HCT116 and HT-29 spheroid growth and inhibits proliferation of HCT116 and HT-29 cells. It induces cell cycle arrest at the G0/G1 phase and increases E-cadherin and β-catenin protein levels in HCT116 cells when used at a concentration of 40 μM.