Sivelestat
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- $50 - $1754.55
- Product name: Sivelestat
- CAS: 127373-66-4
- MF: C20H22N2O7S
- MW: 434.46
- EINECS:
- MDL Number:MFCD00889071
- Synonyms:EI 546 sodium salt hydrate;Elaspol sodium salt hydrate;LY 544349 sodium salt hydrate;o-(p-Hydroxybenzenesulfonamido)hippuric acid, pivalate (ester) sodium salt hydrate;Ono-5046 sodium salt hydrate;Sivelestat sodium salt hydrate;Sivelestat (ONO-5046);2-[[2-[[4-(2,2-dimethylpropanoyloxy)phenyl]sulfonylamino]benzoyl]amino]acetic acid
24 prices
Selected condition：
Brand
- Activate Scientific
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 1g
- 5G
- ManufacturerActivate Scientific
- Product numberAS148193
- Product descriptionSivelestat 98%
- Packaging1g
- Price$381
- Updated2021-12-16
- Buy
- ManufacturerActivate Scientific
- Product numberAS148193
- Product descriptionSivelestat 98%
- Packaging5G
- Price$1332
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberP528
- Product descriptionSivelestat
- Packaging5mg
- Price$367
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA310710
- Product descriptionSivelestat 98+%
- Packaging250mg
- Price$112
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA310710
- Product descriptionSivelestat 98+%
- Packaging1g
- Price$284
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA310710
- Product descriptionSivelestat 98+%
- Packaging5g
- Price$1001
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000053
- Product descriptionSIVELESTAT 95.00%
- Packaging5MG
- Price$501.96
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000053
- Product descriptionSIVELESTAT 95.00%
- Packaging5G
- Price$1754.55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6189
- Product descriptionSivelestat(ONO-5046)
- Packaging10mg
- Price$68
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6189
- Product descriptionSivelestat(ONO-5046)
- Packaging50mg
- Price$243
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6189
- Product descriptionSivelestat(ONO-5046)
- Packaging200mg
- Price$558
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611543
- Product descriptionSivelestat
- Packaging50mg
- Price$399.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611543
- Product descriptionSivelestat
- Packaging100mg
- Price$680
- Updated2021-12-16
- Buy
- ManufacturerChemenu
- Product numberCM160552
- Product description(2-((4-(pivaloyloxy)phenyl)sulfonamido)benzoyl)glycine 98%
- Packaging50mg
- Price$213
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-2919
- Product descriptionSivelestat 98.26%
- Packaging10mg
- Price$84
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-2919
- Product descriptionSivelestat 98.26%
- Packaging50mg
- Price$288
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Activate Scientific | AS148193 | Sivelestat 98% | 1g | $381 | 2021-12-16 | Buy |
| Activate Scientific | AS148193 | Sivelestat 98% | 5G | $1332 | 2021-12-16 | Buy |
| AK Scientific | P528 | Sivelestat | 5mg | $367 | 2021-12-16 | Buy |
| Ambeed | A310710 | Sivelestat 98+% | 250mg | $112 | 2021-12-16 | Buy |
| Ambeed | A310710 | Sivelestat 98+% | 1g | $284 | 2021-12-16 | Buy |
| Ambeed | A310710 | Sivelestat 98+% | 5g | $1001 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000053 | SIVELESTAT 95.00% | 5MG | $501.96 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000053 | SIVELESTAT 95.00% | 5G | $1754.55 | 2021-12-16 | Buy |
| ApexBio Technology | B6189 | Sivelestat(ONO-5046) | 10mg | $68 | 2021-12-16 | Buy |
| ApexBio Technology | B6189 | Sivelestat(ONO-5046) | 50mg | $243 | 2021-12-16 | Buy |
| ApexBio Technology | B6189 | Sivelestat(ONO-5046) | 200mg | $558 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611543 | Sivelestat | 50mg | $399.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611543 | Sivelestat | 100mg | $680 | 2021-12-16 | Buy |
| Chemenu | CM160552 | (2-((4-(pivaloyloxy)phenyl)sulfonamido)benzoyl)glycine 98% | 50mg | $213 | 2021-12-16 | Buy |
| ChemScene | CS-2919 | Sivelestat 98.26% | 10mg | $84 | 2021-12-16 | Buy |
| ChemScene | CS-2919 | Sivelestat 98.26% | 50mg | $288 | 2021-12-16 | Buy |
Properties
Melting point :218-220°
Density :1.369±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO: soluble10mg/mL, clear
form :White to off-white solid
pka :3.67±0.10(Predicted)
color :white to off-white
InChIKey :BTGNGJJLZOIYID-UHFFFAOYSA-N
Density :1.369±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO: soluble10mg/mL, clear
form :White to off-white solid
pka :3.67±0.10(Predicted)
color :white to off-white
InChIKey :BTGNGJJLZOIYID-UHFFFAOYSA-N
Safety Information
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Description
Sivelestat is a cell-permeable sulfanilide compound that acts as a potent, substrate-competitive, and highly specific inhibitor of neutrophil elastase (IC50 = 19-49 nM in rat, rabbit, hamster, human, and mouse leukocyte elastase). Sivelestat displays >100-fold greater selectivity over pancreas elastase (IC50 = 5.6 μM). Sivelestat does not inhibit trypsin, thrombin, plasmin, kallikrein, chymotrypsin, and cathepsin G even at concentrations as high as 100 μM. Sivelestat effectively suppresses human neutrophil elastase-induced lung hemorrhage and skin capillary permeability. Sivelestat is also reported to inhibit mast cell Stat6-protease.More related product prices
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