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ChemicalBook >> CAS DataBase List >> Slv320

Slv320

Slv320 price.
  • $18 - $1100
  • Product name: Slv320
  • CAS: 251945-92-3
  • MF: C18H20N4O
  • MW: 308.38
  • EINECS:
  • MDL Number:
  • Synonyms:Cyclohexanol, 4-((2-phenyl-1H-pyrrolo(2,3-D)pyrimidin-4-yl)amino)-, trans-;Slv320;trans-4-[(2-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexanol;(1R,4R)-4-(2-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclohexanol;SC-204288;Derenofylline;4-[(2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexanol;SLV320; SLV-320; SLV 320; DERENOFYLLINE
24 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • CSNpharm
  • DC Chemicals
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 50
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number4484CR
  • Product descriptionDerenofylline
  • Packaging50mg
  • Price$509
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA887654
  • Product descriptionSlv320 98%
  • Packaging5mg
  • Price$18
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA887654
  • Product descriptionSlv320 98%
  • Packaging10mg
  • Price$27
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA887654
  • Product descriptionSlv320 98%
  • Packaging100mg
  • Price$128
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA887654
  • Product descriptionSlv320 98%
  • Packaging250mg
  • Price$255
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA887654
  • Product descriptionSlv320 98%
  • Packaging1g
  • Price$635
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0005746
  • Product descriptionTRANS-4-[2-[PHENYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)AMINO]-CYCLOHEXANOL 95.00%
  • Packaging5MG
  • Price$505.47
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7373
  • Product descriptionSLV320
  • Packaging5mg
  • Price$162
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7373
  • Product descriptionSLV320
  • Packaging10mg
  • Price$270
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number27666
  • Product descriptionDerenofylline
  • Packaging1mg
  • Price$34
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27666
  • Product descriptionDerenofylline
  • Packaging5mg
  • Price$92
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27666
  • Product descriptionDerenofylline
  • Packaging10mg
  • Price$166
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27666
  • Product descriptionDerenofylline
  • Packaging25mg
  • Price$371
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0003600
  • Product descriptionDerenofylline >99.0%
  • Packaging5mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0003600
  • Product descriptionDerenofylline >99.0%
  • Packaging10mg
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0003600
  • Product descriptionDerenofylline >99.0%
  • Packaging25mg
  • Price$280
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4484CR Derenofylline 50mg $509 2021-12-16 Buy
Ambeed A887654 Slv320 98% 5mg $18 2021-12-16 Buy
Ambeed A887654 Slv320 98% 10mg $27 2021-12-16 Buy
Ambeed A887654 Slv320 98% 100mg $128 2021-12-16 Buy
Ambeed A887654 Slv320 98% 250mg $255 2021-12-16 Buy
Ambeed A887654 Slv320 98% 1g $635 2021-12-16 Buy
American Custom Chemicals Corporation API0005746 TRANS-4-[2-[PHENYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)AMINO]-CYCLOHEXANOL 95.00% 5MG $505.47 2021-12-16 Buy
ApexBio Technology B7373 SLV320 5mg $162 2021-12-16 Buy
ApexBio Technology B7373 SLV320 10mg $270 2021-12-16 Buy
Cayman Chemical 27666 Derenofylline 1mg $34 2024-03-01 Buy
Cayman Chemical 27666 Derenofylline 5mg $92 2024-03-01 Buy
Cayman Chemical 27666 Derenofylline 10mg $166 2024-03-01 Buy
Cayman Chemical 27666 Derenofylline 25mg $371 2024-03-01 Buy
ChemScene CS-0003600 Derenofylline >99.0% 5mg $80 2021-12-16 Buy
ChemScene CS-0003600 Derenofylline >99.0% 10mg $130 2021-12-16 Buy
ChemScene CS-0003600 Derenofylline >99.0% 25mg $280 2021-12-16 Buy

Properties

Boiling point :532.3±60.0 °C(Predicted)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :Soluble to 100 mM in DMSO and to 50 mM in ethanol
form :Powder
pka :15.15±0.40(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Derenofylline is an adenosine A1 receptor antagonist (Ki = 1 nM). It is selective for adenosine A1 over A2A, A2B, and A3 receptors (Kis = 398, 3,981, and 200 nM, respectively). It decreases adenosine A1 receptor-mediated adenosine-induced bradycardia in rats (ED50 = 0.49 mg/kg) but reduces A2 receptor-mediated adenosine-induced hypotension by only 44.6% when administered at an intravenous dose of 5 mg/kg. It prevents increases in heart levels of collagen I and III in nephrectomized rats when administered at a dose of 10 mg/kg per day. Derenofylline also reduces relative plaque counts in a Zika virus plaque-forming assay in A549 cells (IC50 = 58.6 nM) in an adenosine A1 receptor-independent manner without inducing cytotoxicity when used at concentrations less than 10 μM.