Streptochlorin
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- $80 - $844
- Product name: Streptochlorin
- CAS: 120191-51-7
- MF: C11H7ClN2O
- MW: 218.63908
- EINECS:
- MDL Number:MFCD18449873
- Synonyms:Streptochlorin;3-(4-Chloro-5-oxazolyl)-1H-indole;Antibiotic SF 2583A;SF 2583A;1H-Indole, 3-(4-chloro-5-oxazolyl)-;4-Chloro-5-(1H-indol-3-yl)oxazole
7 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
- Usbiological
Package
- 250ug
- 250μg
- 1mg
- 5MG
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0141-C250
- Product descriptionStreptochlorin ≥95%(HPLC)
- Packaging250μg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0141-M001
- Product descriptionStreptochlorin ≥95%(HPLC)
- Packaging1mg
- Price$240
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3685DF
- Product descriptionStreptochlorin
- Packaging1mg
- Price$417
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0009883
- Product descriptionSTREPTOCHLORIN 95.00%
- Packaging5MG
- Price$456.05
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number27605
- Product descriptionStreptochlorin
- Packaging1mg
- Price$225
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27605
- Product descriptionStreptochlorin
- Packaging5mg
- Price$844
- Updated2024-03-01
- Buy
- ManufacturerUsbiological
- Product number207409
- Product descriptionStreptochlorin
- Packaging250ug
- Price$316
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CN2-0141-C250 | Streptochlorin ≥95%(HPLC) | 250μg | $80 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CN2-0141-M001 | Streptochlorin ≥95%(HPLC) | 1mg | $240 | 2021-12-16 | Buy |
| AK Scientific | 3685DF | Streptochlorin | 1mg | $417 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0009883 | STREPTOCHLORIN 95.00% | 5MG | $456.05 | 2021-12-16 | Buy |
| Cayman Chemical | 27605 | Streptochlorin | 1mg | $225 | 2024-03-01 | Buy |
| Cayman Chemical | 27605 | Streptochlorin | 5mg | $844 | 2024-03-01 | Buy |
| Usbiological | 207409 | Streptochlorin | 250ug | $316 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMSO: soluble; Methanol: soluble
form :A solid
color :Crystalline
solubility :DMSO: soluble; Methanol: soluble
form :A solid
color :Crystalline
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Streptochlorin is a bacterial metabolite originally isolated from Streptomyces sp. SF2583 that has diverse biological activities, including antiangiogenic, antiproliferative, and anti-allergic properties. It inhibits TNF-α-induced NF-κB transcriptional activity and decreases proliferation of human umbilical vein endothelial cells (HUVECs) when used at concentrations ranging from 5 to 20 μM. Streptochlorin (12 μg/ml) decreases viability of, as well as induces apoptosis and increases the production of reactive oxygen species (ROS) in, Hep3B human hepatocellular carcinoma cells. It does not induce cytotoxicity in RBL-2H3 mast cells at concentrations up to 100 μM. Streptochlorin prevents degranulation in antigen-stimulated mast cells, as well as inhibits Syk kinase and the Src family kinases LYN and Fyn and reduces the secretion of TNF-α and IL-4 induced by dinitrophenyl-human serum album (DNP-HSA) in RBL-2H3 mast cells. It also decreases swelling and reduces scratching behavior in a mouse model of allergic dermatitis induced by dinitrofluorobenzene (DNFB).Suppliers and manufacturers
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