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ChemicalBook >> CAS DataBase List >> TA-01

TA-01

TA-01 price.
  • $32 - $875
  • Product name: TA-01
  • CAS: 1784751-18-3
  • MF: C20H12F3N3
  • MW: 351.32
  • EINECS:
  • MDL Number:MFCD30182287
  • Synonyms:TA-01;TA-01;TA01;TA 01;Pyridine, 4-[2-(2,6-difluorophenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]-;4-(2-(2,6-Difluorophenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl)pyridine;TA 01,Inhibitor,Casein Kinase,Autophagy,p38 MAPK,inhibit,TA01,TA-01
17 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 5mg
  • 10mM(in 1mL DMSO)
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number0467EC
  • Product descriptionCID91691129
  • Packaging1mg
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number0467EC
  • Product descriptionCID91691129
  • Packaging10mg
  • Price$403
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4923
  • Product descriptionTA01
  • Packaging10mM(in 1mL DMSO)
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number24667
  • Product descriptionTA-01 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number24667
  • Product descriptionTA-01 ≥98%
  • Packaging5mg
  • Price$145
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number24667
  • Product descriptionTA-01 ≥98%
  • Packaging10mg
  • Price$275
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number24667
  • Product descriptionTA-01 ≥98%
  • Packaging25mg
  • Price$571
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5588
  • Product descriptionTA-01 99.93%
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5588
  • Product descriptionTA-01 99.93%
  • Packaging10mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5588
  • Product descriptionTA-01 99.93%
  • Packaging50mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5588
  • Product descriptionTA-01 99.93%
  • Packaging100mg
  • Price$800
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002940
  • Product descriptionTA-01 98+%
  • Packaging5mg
  • Price$84
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002940
  • Product descriptionTA-01 98+%
  • Packaging10mg
  • Price$126
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002940
  • Product descriptionTA-01 98+%
  • Packaging50mg
  • Price$504
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9301
  • Product descriptionTA-01 >98%
  • Packaging100mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9301
  • Product descriptionTA-01 >98%
  • Packaging250mg
  • Price$700
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 0467EC CID91691129 1mg $133 2021-12-16 Buy
AK Scientific 0467EC CID91691129 10mg $403 2021-12-16 Buy
ApexBio Technology B4923 TA01 10mM(in 1mL DMSO) $120 2021-12-16 Buy
Cayman Chemical 24667 TA-01 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 24667 TA-01 ≥98% 5mg $145 2024-03-01 Buy
Cayman Chemical 24667 TA-01 ≥98% 10mg $275 2024-03-01 Buy
Cayman Chemical 24667 TA-01 ≥98% 25mg $571 2024-03-01 Buy
ChemScene CS-5588 TA-01 99.93% 5mg $120 2021-12-16 Buy
ChemScene CS-5588 TA-01 99.93% 10mg $200 2021-12-16 Buy
ChemScene CS-5588 TA-01 99.93% 50mg $600 2021-12-16 Buy
ChemScene CS-5588 TA-01 99.93% 100mg $800 2021-12-16 Buy
Crysdot CD31002940 TA-01 98+% 5mg $84 2021-12-16 Buy
Crysdot CD31002940 TA-01 98+% 10mg $126 2021-12-16 Buy
Crysdot CD31002940 TA-01 98+% 50mg $504 2021-12-16 Buy
DC Chemicals DC9301 TA-01 >98% 100mg $350 2021-12-16 Buy
DC Chemicals DC9301 TA-01 >98% 250mg $700 2021-12-16 Buy

Properties

Boiling point :511.1±50.0 °C(Predicted)
Density :1.337±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 5 mg/ml; DMF:PBS(pH 7.2)(1:6): 0.14 mg/ml; DMSO: 3 mg/ml
form :A crystalline solid
pka :9.26±0.24(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

TA-01 is a derivative of the p38 MAPK inhibitor SB 203580 (Item Nos. 13067 | 13344) and an inducer of cardiomyocyte differentiation. It is cardiomyogenic at concentrations less than 5 μM, increasing expression of the cardiomyocyte marker NKX2-5 by 2.2-fold and decreasing expression of mesoderm markers and the pre-cardiac marker Isl-1 in HES-3 NKX2-5eGFP/w cells when applied after embryoid body formation. TA-01 inhibits casein kinase 1ε (CK1ε) and CK1Δ and reduces expression of Wnt/β-catenin signaling pathway members, activities that positively correlate with its cardiomyogenic activity.

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