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ChemicalBook >> TMPH HYDROCHLORIDE

TMPH HYDROCHLORIDE

TMPH HYDROCHLORIDE price.
  • $135 - $1041.76
  • Product name: TMPH HYDROCHLORIDE
  • CAS: 849461-91-2
  • MF: C16H32ClNO2
  • MW: 305.89
  • EINECS:
  • MDL Number:MFCD08277030
  • Synonyms:TMPH HCl
7 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Sigma-Aldrich
  • TRC
Package
  • 5mg
  • 10MG
  • 25mg
  • 50MG
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008363
  • Product descriptionTMPH HYDROCHLORIDE 95.00%
  • Packaging10MG
  • Price$660.95
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008363
  • Product descriptionTMPH HYDROCHLORIDE 95.00%
  • Packaging50MG
  • Price$1041.76
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7053
  • Product descriptionTMPH hydrochloride
  • Packaging10mg
  • Price$219
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7053
  • Product descriptionTMPH hydrochloride
  • Packaging50mg
  • Price$896
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberT5576
  • Product descriptionTMPH hydrochloride solid, (Product is pure based on CHN, NMR and MS results)
  • Packaging5mg
  • Price$228
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberT5576
  • Product descriptionTMPH hydrochloride solid, (Product is pure based on CHN, NMR and MS results)
  • Packaging25mg
  • Price$727
  • Updated2022-05-15
  • Buy
  • ManufacturerTRC
  • Product numberT460013
  • Product descriptionTMPH hydrochloride
  • Packaging5mg
  • Price$135
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0008363 TMPH HYDROCHLORIDE 95.00% 10MG $660.95 2021-12-16 Buy
American Custom Chemicals Corporation API0008363 TMPH HYDROCHLORIDE 95.00% 50MG $1041.76 2021-12-16 Buy
ApexBio Technology B7053 TMPH hydrochloride 10mg $219 2021-12-16 Buy
ApexBio Technology B7053 TMPH hydrochloride 50mg $896 2021-12-16 Buy
Sigma-Aldrich T5576 TMPH hydrochloride solid, (Product is pure based on CHN, NMR and MS results) 5mg $228 2024-03-01 Buy
Sigma-Aldrich T5576 TMPH hydrochloride solid, (Product is pure based on CHN, NMR and MS results) 25mg $727 2022-05-15 Buy
TRC T460013 TMPH hydrochloride 5mg $135 2021-12-16 Buy

Properties

storage temp. :2-8°C
solubility :H2O: 22 mg/mL at ~60 °C
form :solid
color :white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

TMPH hydrochloride is a potent inhibitor of neuronal AChRs. Evaluation of AChR subunits expressed in Xenopus laevis oocytes indicated that TMPH can produce a potent and long-lasting inhibition of neuronal AChR formed by the pairwise combination of the most abundant neuronal α (i.e., α3 and α4) and β subunits (β2 and β4), with relatively little effect, because of rapid reversibility of inhibition, on muscle-type (α1β1γδ) or α7 receptors. However, the inhibition of neuronal β subunit-containing receptors was also decreased if any of the nonessential subunits α5, α6, or β3 were coexpressed. This decrease in inhibition is shown to be associated with a single amino acid present in the second transmembrane domain of these subunits. TMPH ability to relate the diverse central nervous system effects to specific AChR subtypes makes it a helpful tool for studying the functional roles of AChR.