TOLAZAMIDE
- $5 - $1593.9
- Product name: TOLAZAMIDE
- CAS: 1156-19-0
- MF: C14H21N3O3S
- MW: 311.4
- EINECS:214-588-3
- MDL Number:MFCD00083504
- Synonyms:1-(hexahydro-1-azepinyl)-3-p-tolylsulfonylurea ;1-(hexahydro-1h-azepin-1-yl)-3-(p-tolylsulfonyl)-ure ;1-(hexahydro-1h-azepin-1-yl)-3-(p-tolylsulfonyl)urea ;4-(p-tolylsulfonyl)-1,1-hexamethylenesemicarbazide ;Tolazamide Solution, 100ppm;diabewas ;n-(((hexahydro-1h-azepin-1-yl)-amino)carbonyl)-4-methyl-benzenesulfonamid ;n-(p-toluenesulfonyl)-n’-hexamethyleniminourea
29 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- Arctom
- Biosynth Carbosynth
- Cayman Chemical
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 1g
- 5g
- ManufacturerAK Scientific
- Product number2761AH
- Product descriptionTolazamide
- Packaging10mg
- Price$166
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2761AH
- Product descriptionTolazamide
- Packaging50mg
- Price$267
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA899724
- Product descriptionTolazamide 98+%
- Packaging1mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA899724
- Product descriptionTolazamide 98+%
- Packaging10mg
- Price$15
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA899724
- Product descriptionTolazamide 98+%
- Packaging50mg
- Price$32
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA899724
- Product descriptionTolazamide 98+%
- Packaging100mg
- Price$48
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA899724
- Product descriptionTolazamide 98+%
- Packaging250mg
- Price$71
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA899724
- Product descriptionTolazamide 98+%
- Packaging1g
- Price$176
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA899724
- Product descriptionTolazamide 98+%
- Packaging5g
- Price$581
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004439
- Product descriptionTOLAZAMIDE 95.00%
- Packaging10MG
- Price$280.35
- Updated2021-12-16
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- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004439
- Product descriptionTOLAZAMIDE 95.00%
- Packaging100MG
- Price$704.55
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004439
- Product descriptionTOLAZAMIDE 95.00%
- Packaging1G
- Price$1593.9
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS691309
- Product descriptionTolazamide ≥98%
- Packaging250mg
- Price$66
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS691309
- Product descriptionTolazamide ≥98%
- Packaging1g
- Price$172
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS691309
- Product descriptionTolazamide ≥98%
- Packaging5g
- Price$530
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFT61359
- Product descriptionTolazamide
- Packaging10mg
- Price$95
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 2761AH | Tolazamide | 10mg | $166 | 2021-12-16 | Buy |
AK Scientific | 2761AH | Tolazamide | 50mg | $267 | 2021-12-16 | Buy |
Ambeed | A899724 | Tolazamide 98+% | 1mg | $5 | 2021-12-16 | Buy |
Ambeed | A899724 | Tolazamide 98+% | 10mg | $15 | 2021-12-16 | Buy |
Ambeed | A899724 | Tolazamide 98+% | 50mg | $32 | 2021-12-16 | Buy |
Ambeed | A899724 | Tolazamide 98+% | 100mg | $48 | 2021-12-16 | Buy |
Ambeed | A899724 | Tolazamide 98+% | 250mg | $71 | 2021-12-16 | Buy |
Ambeed | A899724 | Tolazamide 98+% | 1g | $176 | 2021-12-16 | Buy |
Ambeed | A899724 | Tolazamide 98+% | 5g | $581 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0004439 | TOLAZAMIDE 95.00% | 10MG | $280.35 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0004439 | TOLAZAMIDE 95.00% | 100MG | $704.55 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0004439 | TOLAZAMIDE 95.00% | 1G | $1593.9 | 2021-12-16 | Buy |
Arctom | AS691309 | Tolazamide ≥98% | 250mg | $66 | 2021-12-16 | Buy |
Arctom | AS691309 | Tolazamide ≥98% | 1g | $172 | 2021-12-16 | Buy |
Arctom | AS691309 | Tolazamide ≥98% | 5g | $530 | 2021-12-16 | Buy |
Biosynth Carbosynth | FT61359 | Tolazamide | 10mg | $95 | 2021-12-16 | Buy |
Properties
Melting point :162-164°C
Boiling point :300°C (rough estimate)
Density :1.2228 (rough estimate)
refractive index :1.6740 (estimate)
storage temp. :Sealed in dry,Room Temperature
solubility :Very slightly soluble in water; freely soluble in chloroform; soluble in acetone; slightly soluble in ethanol (96%).
form :Solid
pka :3.6(at 25℃)
color :White to Off-White
Water Solubility :65.4mg/L(30 ºC)
CAS DataBase Reference :1156-19-0(CAS DataBase Reference)
EPA Substance Registry System :Tolazamide (1156-19-0)
Boiling point :300°C (rough estimate)
Density :1.2228 (rough estimate)
refractive index :1.6740 (estimate)
storage temp. :Sealed in dry,Room Temperature
solubility :Very slightly soluble in water; freely soluble in chloroform; soluble in acetone; slightly soluble in ethanol (96%).
form :Solid
pka :3.6(at 25℃)
color :White to Off-White
Water Solubility :65.4mg/L(30 ºC)
CAS DataBase Reference :1156-19-0(CAS DataBase Reference)
EPA Substance Registry System :Tolazamide (1156-19-0)
Safety Information
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Signal word: | Danger | ||||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
Tolazamide is a first generation sulfonylurea that inhibits sulfonylurea receptor 1 (SUR1) linked to the inwardly rectifying potassium channel (KIR6.2; IC50 = 4.2 μM in HEK293 cells transfected with the human receptor). It has no effect on glucose uptake in L6 rat skeletal muscle cells when used at a concentration of 0.6 mg/mL but enhances glucose uptake two-fold when used in combination with insulin. In vivo, tolazamide (128 mg/kg) reduces glomerulosclerosis and albumin excretion in a rat model of insulin-dependent diabetes induced by streptozotocin . Formulations containing tolazamide have been used in the treatment of type 2 diabetes.Related product price
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