TUNICAMYCIN
- $32 - $943
- Product name: TUNICAMYCIN
- CAS: 11089-65-9
- MF: C37H60N4O16
- MW: 816.89
- EINECS:601-012-4
- MDL Number:MFCD00065709
- Synonyms:Aids010655;Aids-010655;Nsc177382;TunicaMycin froM StreptoMyces lysosuperficus;TunicaMycin coMplex;InSolution? Tunicamycin,;TUNICAMYCIN, STREPTOMYCES IYSOSUPERFICUS;TUNICAMYCIN, STREPTOMYCES LYSOSUPERFICUS
28 prices
Selected condition:
Brand
- AK Scientific
- Alfa Aesar
- ApexBio Technology
- Apolloscientific
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 2mg
- 5045700001
- 1mg
- 5mg
- 10
- 2.5mg
- 10mg
- 25mg
- 50mg
- 1ml
- ManufacturerAK Scientific
- Product number9176AJ
- Product descriptionTunicamycin
- Packaging10mg
- Price$268
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ62217
- Product descriptionTunicamycin 95%
- Packaging10mg
- Price$243
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ67401
- Product descriptionTunicamycin, 10 mg/ml in DMSO sterile-filtered
- Packaging1ml
- Price$485
- Updated2024-03-01
- Buy
- ManufacturerApexBio Technology
- Product numberB7417
- Product descriptionTunicamycin
- Packaging5mg
- Price$97
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7417
- Product descriptionTunicamycin
- Packaging10mg
- Price$144
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIT1006
- Product descriptionTunicamycin from Streptomyces sp.
- Packaging1mg
- Price$68
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIT1006
- Product descriptionTunicamycin from Streptomyces sp.
- Packaging5mg
- Price$169
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIT1006
- Product descriptionTunicamycin from Streptomyces sp.
- Packaging10mg
- Price$291
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545981
- Product descriptionTunicamycin >98%
- Packaging5mg
- Price$197.2
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545981
- Product descriptionTunicamycin >98%
- Packaging25mg
- Price$549.1
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number11445
- Product descriptionTunicamycin ≥95% (mixture of isomers)
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11445
- Product descriptionTunicamycin ≥95% (mixture of isomers)
- Packaging5mg
- Price$86
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11445
- Product descriptionTunicamycin ≥95% (mixture of isomers)
- Packaging10mg
- Price$153
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-5779
- Product descriptionTunicamycin 99.69%
- Packaging2mg
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5779
- Product descriptionTunicamycin 99.69%
- Packaging5mg
- Price$385
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5779
- Product descriptionTunicamycin 99.69%
- Packaging10mg
- Price$650
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 9176AJ | Tunicamycin | 10mg | $268 | 2021-12-16 | Buy |
Alfa Aesar | J62217 | Tunicamycin 95% | 10mg | $243 | 2024-03-01 | Buy |
Alfa Aesar | J67401 | Tunicamycin, 10 mg/ml in DMSO sterile-filtered | 1ml | $485 | 2024-03-01 | Buy |
ApexBio Technology | B7417 | Tunicamycin | 5mg | $97 | 2021-12-16 | Buy |
ApexBio Technology | B7417 | Tunicamycin | 10mg | $144 | 2021-12-16 | Buy |
Apolloscientific | BIT1006 | Tunicamycin from Streptomyces sp. | 1mg | $68 | 2021-12-16 | Buy |
Apolloscientific | BIT1006 | Tunicamycin from Streptomyces sp. | 5mg | $169 | 2021-12-16 | Buy |
Apolloscientific | BIT1006 | Tunicamycin from Streptomyces sp. | 10mg | $291 | 2021-12-16 | Buy |
Biorbyt Ltd | orb545981 | Tunicamycin >98% | 5mg | $197.2 | 2021-12-16 | Buy |
Biorbyt Ltd | orb545981 | Tunicamycin >98% | 25mg | $549.1 | 2021-12-16 | Buy |
Cayman Chemical | 11445 | Tunicamycin ≥95% (mixture of isomers) | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 11445 | Tunicamycin ≥95% (mixture of isomers) | 5mg | $86 | 2024-03-01 | Buy |
Cayman Chemical | 11445 | Tunicamycin ≥95% (mixture of isomers) | 10mg | $153 | 2024-03-01 | Buy |
ChemScene | CS-5779 | Tunicamycin 99.69% | 2mg | $190 | 2021-12-16 | Buy |
ChemScene | CS-5779 | Tunicamycin 99.69% | 5mg | $385 | 2021-12-16 | Buy |
ChemScene | CS-5779 | Tunicamycin 99.69% | 10mg | $650 | 2021-12-16 | Buy |
Properties
Melting point :234-235℃ (decomposition)
alpha :D20 +52° (c = 0.5 in pyridine)
Flash point :87℃
storage temp. :2-8°C
solubility :Soluble in methanol, ethanol, DMSO, or DMF
form :White to off-white solid
color :White
Sensitive :Moisture & Light Sensitive
BRN :6888090
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChIKey :YJQCOFNZVFGCAF-WPTOCQRYSA-N
EPA Substance Registry System :Tunicamycin (11089-65-9)
alpha :D20 +52° (c = 0.5 in pyridine)
Flash point :87℃
storage temp. :2-8°C
solubility :Soluble in methanol, ethanol, DMSO, or DMF
form :White to off-white solid
color :White
Sensitive :Moisture & Light Sensitive
BRN :6888090
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChIKey :YJQCOFNZVFGCAF-WPTOCQRYSA-N
EPA Substance Registry System :Tunicamycin (11089-65-9)
Safety Information
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Signal word: | Danger | ||||||||||||||
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Precautionary statements: |
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Description
N-linked glycosylation is a highly regulated post-translational modification that is involved in protein folding and conformation, oligomerization, sorting, cell-cell interactions, and targeting of proteins to sub- or extra-cellular locations. It is initiated in the endoplastic reticulum with the transfer of a carbohydrate moiety to an asparagine residue within a specific amino acid consensus sequence and then further processed in the Golgi whereupon a mature glycoprotein is exported through the secretory machinery to the plasma membrane. Tunicamycin, a nucleoside antibiotic, is a specific inhibitor of N-linked glycoslylation that blocks the first step of glycoprotein synthesis thereby inducing protein unfolding. At 500 nM, it can impair the function of several receptor tyrosine kinases, including EGFR, ErbB2, ErbB3, and IGF-IR. Also at 500 nM, it radiosensitizes U251 glioma and BXPC3 pancreatic adenocarcinoma cells to chemotherapy. Tunicamycin impairs ALK phosphorylation and disrupts pro-survival signaling and cell viability in various neuroblastoma cell lines (IC50s range from 20 - 500 nM). Tunicamycin can also inhibit protein palmitoylation.Related product price
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Suppliers and manufacturers
Hangzhou FandaChem Co.,Ltd.
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TargetMol Chemicals Inc.
Hubei Ipure Biology Co., Ltd
Zhejiang Huida Biotech Co., LTD
HONG KONG IPURE BIOLOGY CO.,LIMITED