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ChemicalBook >> CAS DataBase List >> TYRPHOSTIN A25

TYRPHOSTIN A25

TYRPHOSTIN A25 price.
  • $28 - $2000
  • Product name: TYRPHOSTIN A25
  • CAS: 118409-58-8
  • MF: C10H6N2O3
  • MW: 202.17
  • EINECS:
  • MDL Number:MFCD00133900
  • Synonyms:[3,4,5-TRIHYDROXYBENZYLIDENE]MALONONITRILE;AG 82;ALPHA-CYANO-(3,4,5-TRIHYDROXY)CINNAMONITRILE;RG-50875;RARECHEM AL BX 0070;TYRPHOSTIN 25;TYRPHOSTIN RG 50875;TYRPHOSTIN AG 82
13 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Medical Isotopes, Inc.
  • TRC
  • Usbiological
Package
  • 5mg
  • 10mg
  • 25MG
  • 50mg
  • 125mg
  • 250MG
  • ManufacturerAK Scientific
  • Product number2089AH
  • Product descriptionTyrphostinA25
  • Packaging5mg
  • Price$128
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001451
  • Product descriptionTYRPHOSTIN A-25 95.00%
  • Packaging5MG
  • Price$137.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001451
  • Product descriptionTYRPHOSTIN A-25 95.00%
  • Packaging25MG
  • Price$721.88
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001451
  • Product descriptionTYRPHOSTIN A-25 95.00%
  • Packaging250MG
  • Price$1732.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4760
  • Product descriptionAG 82
  • Packaging25mg
  • Price$131
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4760
  • Product descriptionAG 82
  • Packaging50mg
  • Price$233
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010312
  • Product descriptionAG 82 ≥95%
  • Packaging5mg
  • Price$28
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010312
  • Product descriptionAG 82 ≥95%
  • Packaging10mg
  • Price$50
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010312
  • Product descriptionAG 82 ≥95%
  • Packaging25mg
  • Price$117
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010312
  • Product descriptionAG 82 ≥95%
  • Packaging50mg
  • Price$207
  • Updated2024-03-01
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number14115
  • Product descriptionTyrphostin25
  • Packaging125mg
  • Price$2000
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberT925000
  • Product descriptionTyrphostin25
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product numberT9250-01
  • Product descriptionTyrphostin 25
  • Packaging25mg
  • Price$425
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2089AH TyrphostinA25 5mg $128 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001451 TYRPHOSTIN A-25 95.00% 5MG $137.5 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001451 TYRPHOSTIN A-25 95.00% 25MG $721.88 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001451 TYRPHOSTIN A-25 95.00% 250MG $1732.5 2021-12-16 Buy
ApexBio Technology C4760 AG 82 25mg $131 2021-12-16 Buy
ApexBio Technology C4760 AG 82 50mg $233 2021-12-16 Buy
Cayman Chemical 10010312 AG 82 ≥95% 5mg $28 2024-03-01 Buy
Cayman Chemical 10010312 AG 82 ≥95% 10mg $50 2024-03-01 Buy
Cayman Chemical 10010312 AG 82 ≥95% 25mg $117 2024-03-01 Buy
Cayman Chemical 10010312 AG 82 ≥95% 50mg $207 2024-03-01 Buy
Medical Isotopes, Inc. 14115 Tyrphostin25 125mg $2000 2021-12-16 Buy
TRC T925000 Tyrphostin25 5mg $50 2021-12-16 Buy
Usbiological T9250-01 Tyrphostin 25 25mg $425 2021-12-16 Buy

Properties

Melting point :~220°C dec.
Boiling point :500.8±50.0 °C(Predicted)
Density :1.569±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >50 mg/mL, clear, yellow to orange
form :Dark yellow solid
pka :7.10±0.23(Predicted)
color :Yellow Green
Stability :Light Sensitive
CAS DataBase Reference :118409-58-8

Safety Information

Symbol(GHS):
Signal word:
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Description

Tyrphostin A25 is a cell-permeable, competitive and reversible inhibitor of substrate binding on protein tyrosine kinases. In cultured rat hepatocytes, Tyrphostin A25 has been shown to inhibit endocytosis of tyramine-cellobiose-asialoorosomucoid (TC-AOM). It has also shown to inhibit neuromedin B-induced phosphorylation of focal adhesion kinase (p125FAK). Inhibits EGFR (epidermal growth factor receptor) tyrosine kinase (IC50=3 M ) and the GTPase activity of transducin. In small cell lung cancer cells tyrphostin A25 has been observed to obstruct neuropeptide and basal stimulated growth. In addition it has blocked the induction of inducible NO synthase in glial cells and in human leukemic cell lines has induced apoptosis.

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