Tie-2 Inhibitor 7
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- $121 - $903
- Product name: Tie-2 Inhibitor 7
- CAS: 1020412-97-8
- MF: C31H35N3O5
- MW: 529.63
- EINECS:
- MDL Number:MFCD28138125
- Synonyms:Tie-2 Inhibitor 7;Tie inhibitor 7;Tie2 inhibitor;TIE2 INHIBITOR;TIE INHIBITOR 7;(S)-5-(4-(((2-((1-Cyclohexylethyl)amino)-2-oxoethyl)((p-tolyloxy)carbonyl)amino)methyl)phenyl)nicotinic acid;3-Pyridinecarboxylic acid, 5-[4-[[[2-[[(1S)-1-cyclohexylethyl]amino]-2-oxoethyl][(4-methylphenoxy)carbonyl]amino]methyl]phenyl]-;Tie2 Inhibitor 7,Tie-2 Inhibitor 7
6 prices
Selected condition：
Brand
- Alichem
- Cayman Chemical
- Crysdot
- DC Chemicals
Package
- 500μg
- 1mg
- 5mg
- 100mg
- ManufacturerAlichem
- Product number1020412978
- Product description(S)-5-(4-(((2-((1-Cyclohexylethyl)amino)-2-oxoethyl)((p-tolyloxy)carbonyl)amino)methyl)phenyl)nicotinicacid
- Packaging100mg
- Price$410.4
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19535
- Product descriptionTie2 Inhibitor 7 ≥95%
- Packaging500μg
- Price$121
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19535
- Product descriptionTie2 Inhibitor 7 ≥95%
- Packaging1mg
- Price$230
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19535
- Product descriptionTie2 Inhibitor 7 ≥95%
- Packaging5mg
- Price$903
- Updated2024-03-01
- Buy
- ManufacturerCrysdot
- Product numberCD11364632
- Product description(S)-5-(4-(((2-((1-Cyclohexylethyl)amino)-2-oxoethyl)((p-tolyloxy)carbonyl)amino)methyl)phenyl)nicotinicacid 97%
- Packaging100mg
- Price$380
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8045
- Product descriptionTie-2inhibitor7 >98%
- Packaging1mg
- Price$200
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Alichem | 1020412978 | (S)-5-(4-(((2-((1-Cyclohexylethyl)amino)-2-oxoethyl)((p-tolyloxy)carbonyl)amino)methyl)phenyl)nicotinicacid | 100mg | $410.4 | 2021-12-16 | Buy |
| Cayman Chemical | 19535 | Tie2 Inhibitor 7 ≥95% | 500μg | $121 | 2024-03-01 | Buy |
| Cayman Chemical | 19535 | Tie2 Inhibitor 7 ≥95% | 1mg | $230 | 2024-03-01 | Buy |
| Cayman Chemical | 19535 | Tie2 Inhibitor 7 ≥95% | 5mg | $903 | 2024-03-01 | Buy |
| Crysdot | CD11364632 | (S)-5-(4-(((2-((1-Cyclohexylethyl)amino)-2-oxoethyl)((p-tolyloxy)carbonyl)amino)methyl)phenyl)nicotinicacid 97% | 100mg | $380 | 2021-12-16 | Buy |
| DC Chemicals | DC8045 | Tie-2inhibitor7 >98% | 1mg | $200 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMF: 14 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2)(1:9): 0.1 mg/ml; Ethanol: 1 mg/ml
form :A crystalline solid
solubility :DMF: 14 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2)(1:9): 0.1 mg/ml; Ethanol: 1 mg/ml
form :A crystalline solid
Safety Information
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Description
Tie2 Inhibitor 7 blocks Tie2 kinase activity with a Ki value of 1.3 μM.. It has been shown to inhibit angiopoietin 1-induced Tie2 autophosphorylation and downstream signaling with an IC50 value of 0.3 μM. This compound can prevent endothelial cell tube formation and aberrant vessel growth in a rat model of Matrigel-induced choroidal neovascularization.Suppliers and manufacturers
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