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ChemicalBook >> CAS DataBase List >> Tiplaxtinin

Tiplaxtinin

Tiplaxtinin price.
  • $44 - $1500
  • Product name: Tiplaxtinin
  • CAS: 393105-53-8
  • MF: C24H16F3NO4
  • MW: 439.38
  • EINECS:
  • MDL Number:MFCD09475615
  • Synonyms:2-(1-benzyl-5-(4-(trifluoromethoxy)phenyl)-1H-indol-3-yl)-2-oxoacetic acid;TIPLAXTININ(PAI-039);1H-Indole-3-aceticacid, a-oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]-;2-[1-benzyl-5-[4-(trifluoromethoxy)phenyl]indol-3-yl]-2-oxo-acetic aci d;tiplasinin;Tiplaxtinin;PAI-039;alpha-Oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]-1H-indole-3-acetic acid
32 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 5mg
  • 1mg
  • 50
  • 10mM(in 1mL DMSO)
  • 10mg
  • 25mg
  • 50mg
  • 2x25mg
  • 100mg
  • 200mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number8764CP
  • Product descriptionTiplasinin
  • Packaging5mg
  • Price$206
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number8764CP
  • Product descriptionTiplasinin
  • Packaging50mg
  • Price$687
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA363712
  • Product descriptionTiplaxtinin 98+%
  • Packaging5mg
  • Price$84
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA363712
  • Product descriptionTiplaxtinin 98+%
  • Packaging10mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA363712
  • Product descriptionTiplaxtinin 98+%
  • Packaging25mg
  • Price$211
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA363712
  • Product descriptionTiplaxtinin 98+%
  • Packaging50mg
  • Price$274
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004725
  • Product descriptionPAI-039 95.00%
  • Packaging5MG
  • Price$295.9
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5906
  • Product descriptionTiplaxtinin(PAI-039)
  • Packaging5mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5906
  • Product descriptionTiplaxtinin(PAI-039)
  • Packaging10mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5906
  • Product descriptionTiplaxtinin(PAI-039)
  • Packaging10mM(in 1mL DMSO)
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5906
  • Product descriptionTiplaxtinin(PAI-039)
  • Packaging50mg
  • Price$320
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1383
  • Product descriptionTiplaxtinin-PAI039 99%
  • Packaging25mg
  • Price$231
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1383
  • Product descriptionTiplaxtinin-PAI039 99%
  • Packaging2x25mg
  • Price$352
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number9000450
  • Product descriptionTiplaxtinin ≥98%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number9000450
  • Product descriptionTiplaxtinin ≥98%
  • Packaging5mg
  • Price$97
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number9000450
  • Product descriptionTiplaxtinin ≥98%
  • Packaging10mg
  • Price$142
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8764CP Tiplasinin 5mg $206 2021-12-16 Buy
AK Scientific 8764CP Tiplasinin 50mg $687 2021-12-16 Buy
Ambeed A363712 Tiplaxtinin 98+% 5mg $84 2021-12-16 Buy
Ambeed A363712 Tiplaxtinin 98+% 10mg $125 2021-12-16 Buy
Ambeed A363712 Tiplaxtinin 98+% 25mg $211 2021-12-16 Buy
Ambeed A363712 Tiplaxtinin 98+% 50mg $274 2021-12-16 Buy
American Custom Chemicals Corporation API0004725 PAI-039 95.00% 5MG $295.9 2021-12-16 Buy
ApexBio Technology B5906 Tiplaxtinin(PAI-039) 5mg $70 2021-12-16 Buy
ApexBio Technology B5906 Tiplaxtinin(PAI-039) 10mg $85 2021-12-16 Buy
ApexBio Technology B5906 Tiplaxtinin(PAI-039) 10mM(in 1mL DMSO) $100 2021-12-16 Buy
ApexBio Technology B5906 Tiplaxtinin(PAI-039) 50mg $320 2021-12-16 Buy
Axon Medchem Axon1383 Tiplaxtinin-PAI039 99% 25mg $231 2021-12-16 Buy
Axon Medchem Axon1383 Tiplaxtinin-PAI039 99% 2x25mg $352 2021-12-16 Buy
Cayman Chemical 9000450 Tiplaxtinin ≥98% 1mg $44 2024-03-01 Buy
Cayman Chemical 9000450 Tiplaxtinin ≥98% 5mg $97 2024-03-01 Buy
Cayman Chemical 9000450 Tiplaxtinin ≥98% 10mg $142 2024-03-01 Buy

Properties

Melting point :164-167℃
Density :1.34
storage temp. :-20°C
solubility :DMSO (Sparingly), Methanol (Slightly)
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P391 Collect spillage. Hazardous to the aquatic environment
P501 Dispose of contents/container to..…

Description

Tiplaxtinin is an inhibitor of plasminogen activator inhibitor 1 (PAI-1; IC50 = 2.7 μM for the human enzyme). It inhibits differentiation of human adipocytes when used at a concentration of 5 μM. Tiplaxtinin (5 and 20 mg/kg) reduces tumor growth and microvessel density in a T24 bladder cancer mouse xenograft model. It prevents carotid artery occlusion, increases the time to occlusive thrombosis, and decreases the thrombus size in a rat model of ferric chloride-induced arterial thrombosis when administered at a dose of 1 mg/kg.

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