Tolbutamide-d9
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- $73 - $1963.5
- Product name: Tolbutamide-d9
- CAS: 1219794-57-6
- MF: C12H18N2O3S
- MW: 270.35
- EINECS:
- MDL Number:
- Synonyms:1-(Butyl-3-(p-tolyl- sulfonyl)urea-d9;3-(p-Tolyl-4-sulfonyl)-1-butylurea-d9;Artosin-d9;Artozin-d9;Mobenol-d9;N-[(ButylaMino-d9)carbonyl]-4-MethylbenzenesulfonaMide;N-Butyl-N'-(4-Methylphenylsulfonyl)urea-d9;Tolylsulfonylbutylurea-d9
9 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
- Medical Isotopes, Inc.
- TRC
Package
- 1mg
- 2.5MG
- 5mg
- 0.01g
- 10mg
- 25MG
- 0.05g
- ManufacturerAK Scientific
- Product number5880DV
- Product descriptionTolbutamide-d9
- Packaging1mg
- Price$179
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberBAR0001590
- Product descriptionTOLBUTAMIDE-D9 95.00%
- Packaging2.5MG
- Price$715
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberBAR0001590
- Product descriptionTOLBUTAMIDE-D9 95.00%
- Packaging25MG
- Price$1963.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number30738
- Product descriptionTolbutamide-d9
- Packaging1mg
- Price$73
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number30738
- Product descriptionTolbutamide-d9
- Packaging5mg
- Price$324
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number30738
- Product descriptionTolbutamide-d9
- Packaging10mg
- Price$575
- Updated2024-03-01
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product numberD2584
- Product descriptionTolbutamide-d9(butyl-d9)
- Packaging0.01g
- Price$780
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product numberD2584
- Product descriptionTolbutamide-d9(butyl-d9)
- Packaging0.05g
- Price$1700
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberT535152
- Product descriptionTolbutamide-d9
- Packaging25mg
- Price$1355
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 5880DV | Tolbutamide-d9 | 1mg | $179 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | BAR0001590 | TOLBUTAMIDE-D9 95.00% | 2.5MG | $715 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | BAR0001590 | TOLBUTAMIDE-D9 95.00% | 25MG | $1963.5 | 2021-12-16 | Buy |
Cayman Chemical | 30738 | Tolbutamide-d9 | 1mg | $73 | 2024-03-01 | Buy |
Cayman Chemical | 30738 | Tolbutamide-d9 | 5mg | $324 | 2024-03-01 | Buy |
Cayman Chemical | 30738 | Tolbutamide-d9 | 10mg | $575 | 2024-03-01 | Buy |
Medical Isotopes, Inc. | D2584 | Tolbutamide-d9(butyl-d9) | 0.01g | $780 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | D2584 | Tolbutamide-d9(butyl-d9) | 0.05g | $1700 | 2021-12-16 | Buy |
TRC | T535152 | Tolbutamide-d9 | 25mg | $1355 | 2021-12-16 | Buy |
Properties
Melting point :108-111°C
storage temp. :Refrigerator
solubility :DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:1): 0.14 mg/ml
form :A solid
color :White to off-white
storage temp. :Refrigerator
solubility :DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:1): 0.14 mg/ml
form :A solid
color :White to off-white
Safety Information
Symbol(GHS): |
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Signal word: | Warning | |||||||
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Precautionary statements: |
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Description
Tolbutamide-d9 is intended for use as an internal standard for the quantification of tolbutamide by GC- or LC-MS. Tolbutamide is an inhibitor of sulfonylurea receptor 1 (SUR1) linked to ATP-sensitive potassium channel Kir6.2 (IC50 = 4.9 μM). It is selective for SUR1/Kir6.2 over SUR2A/Kir6.2 and SUR2B/Kir6.2 channels (IC50s = 85 and 88 μM, respectively). Tolbutamide increases glucose-induced insulin secretion and calcium influx in isolated mouse pancreatic islets. In vivo, tolbutamide (80 mg/kg) reduces blood glucose levels in a mouse model of diabetes induced by streptozotocin (STZ; ). Formulations containing tolbutamide have been used in the treatment of type 2 diabetes.More related product prices
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