Troglitazone
|
- $55 - $2318
- Product name: Troglitazone
- CAS: 97322-87-7
- MF: C24H27NO5S
- MW: 441.54
- EINECS:
- MDL Number:MFCD00878416
- Synonyms:Troglitazone(CS-045);RESULIN(TM);ROMGLIZONE;5-(4-(6-hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl)thiazolidine-2 ;ci991 ;enzopyran-2-yl)methoxy)phenyl)methyl)- ;gr92132x ;rezulin
28 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AHH
- AK Scientific
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10mg
- 50
- 5mg
- 25mg
- 50mg
- 100mg
- 0.5g
- 10
- 1g
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3565-M005
- Product descriptionTroglitazone ≥98%
- Packaging5mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3565-M025
- Product descriptionTroglitazone ≥98%
- Packaging25mg
- Price$210
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberAPI-1400
- Product descriptionTroglitazone 98%
- Packaging0.5g
- Price$620
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberK752
- Product descriptionTroglitazone
- Packaging50mg
- Price$397
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberK752
- Product descriptionTroglitazone
- Packaging1g
- Price$2318
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3893
- Product descriptionTroglitazone
- Packaging10mg
- Price$88
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3893
- Product descriptionTroglitazone
- Packaging50mg
- Price$345
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFT28613
- Product descriptionTroglitazone
- Packaging10mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFT28613
- Product descriptionTroglitazone
- Packaging50mg
- Price$332.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number71750
- Product descriptionTroglitazone ≥98%
- Packaging5mg
- Price$60
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number71750
- Product descriptionTroglitazone ≥98%
- Packaging10mg
- Price$110
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number71750
- Product descriptionTroglitazone ≥98%
- Packaging50mg
- Price$457
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number71750
- Product descriptionTroglitazone ≥98%
- Packaging100mg
- Price$799
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM162783
- Product descriptionTroglitazone 98%
- Packaging50mg
- Price$421
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1634
- Product descriptionTroglitazone 99.53%
- Packaging10mg
- Price$102
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1634
- Product descriptionTroglitazone 99.53%
- Packaging50mg
- Price$408
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CR1-3565-M005 | Troglitazone ≥98% | 5mg | $55 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CR1-3565-M025 | Troglitazone ≥98% | 25mg | $210 | 2021-12-16 | Buy |
| AHH | API-1400 | Troglitazone 98% | 0.5g | $620 | 2021-12-16 | Buy |
| AK Scientific | K752 | Troglitazone | 50mg | $397 | 2021-12-16 | Buy |
| AK Scientific | K752 | Troglitazone | 1g | $2318 | 2021-12-16 | Buy |
| ApexBio Technology | A3893 | Troglitazone | 10mg | $88 | 2021-12-16 | Buy |
| ApexBio Technology | A3893 | Troglitazone | 50mg | $345 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FT28613 | Troglitazone | 10mg | $95 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FT28613 | Troglitazone | 50mg | $332.5 | 2021-12-16 | Buy |
| Cayman Chemical | 71750 | Troglitazone ≥98% | 5mg | $60 | 2024-03-01 | Buy |
| Cayman Chemical | 71750 | Troglitazone ≥98% | 10mg | $110 | 2024-03-01 | Buy |
| Cayman Chemical | 71750 | Troglitazone ≥98% | 50mg | $457 | 2024-03-01 | Buy |
| Cayman Chemical | 71750 | Troglitazone ≥98% | 100mg | $799 | 2024-03-01 | Buy |
| Chemenu | CM162783 | Troglitazone 98% | 50mg | $421 | 2021-12-16 | Buy |
| ChemScene | CS-1634 | Troglitazone 99.53% | 10mg | $102 | 2021-12-16 | Buy |
| ChemScene | CS-1634 | Troglitazone 99.53% | 50mg | $408 | 2021-12-16 | Buy |
Properties
Melting point :184-186°C
Boiling point :657.0±55.0 °C(Predicted)
Density :1.266±0.06 g/cm3(Predicted)
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :DMSO: 20 mg/mL
form :solid
pka :6.34±0.50(Predicted)
color :white to yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey :GXPHKUHSUJUWKP-UHFFFAOYSA-N
CAS DataBase Reference :97322-87-7(CAS DataBase Reference)
Boiling point :657.0±55.0 °C(Predicted)
Density :1.266±0.06 g/cm3(Predicted)
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :DMSO: 20 mg/mL
form :solid
pka :6.34±0.50(Predicted)
color :white to yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey :GXPHKUHSUJUWKP-UHFFFAOYSA-N
CAS DataBase Reference :97322-87-7(CAS DataBase Reference)
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
Troglitazone is a TZD which was approved for the treatment of insulin resistance and hyperglycemia in Type II diabetes, under the trade name Resulin?, but was withdrawn from the market due to hepatotoxicity. Troglitazone is a potent and selective PPARγ agonist. The EC50 values for transactivation of human and mouse PPARγ in a cell-based assay are 0.55 and 0.78 μM, respectively. In the same assay system, no activation of PPARα and PPARδ was observed at concentrations up to 10 μM. Troglitazone binds to the PPARγ ligand-binding domain (LBD) but fails to induce interaction of the PPARγ LBD with the transcriptional coactivators SRC-1, TIF2, AIB1, p300, or TRAP220. Troglitazone also induces cell cycle arrest and apoptosis in several cancer cell lines with an EC50 of 10 μM.Related product price
- CHLOROPHOSPHONAZO III
$55-992 - Benzyl alcohol
$5-15264 - (Trifluoromethoxy)benzene
$6-6476.2
Suppliers and manufacturers
Biochempartner
Chongqing Chemdad Co., Ltd
CONIER CHEM AND PHARMA LIMITED
Career Henan Chemica Co
Finetech Industry Limited
Baoji Guokang Bio-Technology Co., Ltd.
Hefei Hirisun Pharmatech Co., Ltd
