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ChemicalBook >> CAS DataBase List >> Tucidinostat (Chidamide)

Tucidinostat (Chidamide)

Tucidinostat (Chidamide) price.
  • $37 - $1500
  • Product name: Tucidinostat (Chidamide)
  • CAS: 1616493-44-7
  • MF: C22H19FN4O2
  • MW: 390.41
  • EINECS:
  • MDL Number:
  • Synonyms:TUCIDINOSTAT;N-(2-Amino-4-fluorophenyl)-4-[[[(2E)-1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]benzamide;Tucidinostat - Chidamide | HBI-8000 | CS 055 | Epidaza;CS055;CS055; HBI-8000;Benzamide, N-(2-amino-4-fluorophenyl)-4-[[[(2E)-1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]-;HBI-8000, CS-055;Chidamide (Tucidinostat, HBI8000, CS 055)
15 prices
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Brand
  • AK Scientific
  • Axon Medchem
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number2989CT
  • Product descriptionTucidinostat
  • Packaging10mg
  • Price$316
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2893
  • Product descriptionTucidinostat-Chidamide|HBI-8000|CS055|Epidaza 99%
  • Packaging50mg
  • Price$368.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13686
  • Product descriptionChidamide
  • Packaging25mg
  • Price$266
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13686
  • Product descriptionChidamide
  • Packaging10mg
  • Price$195
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13686
  • Product descriptionChidamide
  • Packaging5mg
  • Price$116
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13686
  • Product descriptionChidamide
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0030513
  • Product descriptionTucidinostat ≥98.0%
  • Packaging5mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0030513
  • Product descriptionTucidinostat ≥98.0%
  • Packaging10mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0030513
  • Product descriptionTucidinostat ≥98.0%
  • Packaging25mg
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0030513
  • Product descriptionTucidinostat ≥98.0%
  • Packaging50mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0030513
  • Product descriptionTucidinostat ≥98.0%
  • Packaging100mg
  • Price$560
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7978
  • Product descriptionTucidinostat(Chidamide) >98%
  • Packaging100mg
  • Price$420
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7978
  • Product descriptionTucidinostat(Chidamide) >98%
  • Packaging250mg
  • Price$825
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7978
  • Product descriptionTucidinostat(Chidamide) >98%
  • Packaging1g
  • Price$1500
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberC291980
  • Product descriptionChidamide
  • Packaging250mg
  • Price$1320
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2989CT Tucidinostat 10mg $316 2021-12-16 Buy
Axon Medchem Axon2893 Tucidinostat-Chidamide|HBI-8000|CS055|Epidaza 99% 50mg $368.5 2021-12-16 Buy
Cayman Chemical 13686 Chidamide 25mg $266 2024-03-01 Buy
Cayman Chemical 13686 Chidamide 10mg $195 2024-03-01 Buy
Cayman Chemical 13686 Chidamide 5mg $116 2024-03-01 Buy
Cayman Chemical 13686 Chidamide 1mg $37 2024-03-01 Buy
ChemScene CS-0030513 Tucidinostat ≥98.0% 5mg $70 2021-12-16 Buy
ChemScene CS-0030513 Tucidinostat ≥98.0% 10mg $110 2021-12-16 Buy
ChemScene CS-0030513 Tucidinostat ≥98.0% 25mg $220 2021-12-16 Buy
ChemScene CS-0030513 Tucidinostat ≥98.0% 50mg $350 2021-12-16 Buy
ChemScene CS-0030513 Tucidinostat ≥98.0% 100mg $560 2021-12-16 Buy
DC Chemicals DC7978 Tucidinostat(Chidamide) >98% 100mg $420 2021-12-16 Buy
DC Chemicals DC7978 Tucidinostat(Chidamide) >98% 250mg $825 2021-12-16 Buy
DC Chemicals DC7978 Tucidinostat(Chidamide) >98% 1g $1500 2021-12-16 Buy
TRC C291980 Chidamide 250mg $1320 2021-12-16 Buy

Properties

Boiling point :602.1±55.0 °C(Predicted)
Density :1.336±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
form :A crystalline solid
pka :12.05±0.70(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Chidamide is an inhibitor of histone deacetylases (HDACs; IC50s = 0.095, 0.160, 0.067, 0.733, 0.078, and 0.432 μM for HDAC1-3, 8, 10, and 11, respectively). It is selective for these HDACs over HDAC4-7 and 9 (IC50s = >30 μM for all). Chidamide also inhibits nicotinamide phosphoribosyltransferase (Nampt; IC50 = 2.1 μM). It inhibits cell growth in a panel of 18 cancer cell lines (GI50s = 0.4-40 μM) but has no effect on the growth of non-cancerous CCC-HEK human fetal kidney or CCC-HEL human liver cells (GI50s = >100 μM). In vivo, tucidinostat (12.5, 25, and 50 mg/kg) reduces tumor growth in HCT-8, A549, BEL-7402, and MCF-7 mouse xenograft models.

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