Tucidinostat (Chidamide)
- $37 - $1500
- Product name: Tucidinostat (Chidamide)
- CAS: 1616493-44-7
- MF: C22H19FN4O2
- MW: 390.41
- EINECS:
- MDL Number:
- Synonyms:TUCIDINOSTAT;N-(2-Amino-4-fluorophenyl)-4-[[[(2E)-1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]benzamide;Tucidinostat - Chidamide | HBI-8000 | CS 055 | Epidaza;CS055;CS055; HBI-8000;Benzamide, N-(2-amino-4-fluorophenyl)-4-[[[(2E)-1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]-;HBI-8000, CS-055;Chidamide (Tucidinostat, HBI8000, CS 055)
15 prices
Selected condition:
Brand
- AK Scientific
- Axon Medchem
- Cayman Chemical
- ChemScene
- DC Chemicals
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number2989CT
- Product descriptionTucidinostat
- Packaging10mg
- Price$316
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2893
- Product descriptionTucidinostat-Chidamide|HBI-8000|CS055|Epidaza 99%
- Packaging50mg
- Price$368.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13686
- Product descriptionChidamide
- Packaging1mg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13686
- Product descriptionChidamide
- Packaging5mg
- Price$116
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13686
- Product descriptionChidamide
- Packaging10mg
- Price$195
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13686
- Product descriptionChidamide
- Packaging25mg
- Price$266
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0030513
- Product descriptionTucidinostat ≥98.0%
- Packaging5mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0030513
- Product descriptionTucidinostat ≥98.0%
- Packaging10mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0030513
- Product descriptionTucidinostat ≥98.0%
- Packaging25mg
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0030513
- Product descriptionTucidinostat ≥98.0%
- Packaging50mg
- Price$350
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0030513
- Product descriptionTucidinostat ≥98.0%
- Packaging100mg
- Price$560
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC7978
- Product descriptionTucidinostat(Chidamide) >98%
- Packaging100mg
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC7978
- Product descriptionTucidinostat(Chidamide) >98%
- Packaging250mg
- Price$825
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC7978
- Product descriptionTucidinostat(Chidamide) >98%
- Packaging1g
- Price$1500
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberC291980
- Product descriptionChidamide
- Packaging250mg
- Price$1320
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 2989CT | Tucidinostat | 10mg | $316 | 2021-12-16 | Buy |
Axon Medchem | Axon2893 | Tucidinostat-Chidamide|HBI-8000|CS055|Epidaza 99% | 50mg | $368.5 | 2021-12-16 | Buy |
Cayman Chemical | 13686 | Chidamide | 1mg | $37 | 2024-03-01 | Buy |
Cayman Chemical | 13686 | Chidamide | 5mg | $116 | 2024-03-01 | Buy |
Cayman Chemical | 13686 | Chidamide | 10mg | $195 | 2024-03-01 | Buy |
Cayman Chemical | 13686 | Chidamide | 25mg | $266 | 2024-03-01 | Buy |
ChemScene | CS-0030513 | Tucidinostat ≥98.0% | 5mg | $70 | 2021-12-16 | Buy |
ChemScene | CS-0030513 | Tucidinostat ≥98.0% | 10mg | $110 | 2021-12-16 | Buy |
ChemScene | CS-0030513 | Tucidinostat ≥98.0% | 25mg | $220 | 2021-12-16 | Buy |
ChemScene | CS-0030513 | Tucidinostat ≥98.0% | 50mg | $350 | 2021-12-16 | Buy |
ChemScene | CS-0030513 | Tucidinostat ≥98.0% | 100mg | $560 | 2021-12-16 | Buy |
DC Chemicals | DC7978 | Tucidinostat(Chidamide) >98% | 100mg | $420 | 2021-12-16 | Buy |
DC Chemicals | DC7978 | Tucidinostat(Chidamide) >98% | 250mg | $825 | 2021-12-16 | Buy |
DC Chemicals | DC7978 | Tucidinostat(Chidamide) >98% | 1g | $1500 | 2021-12-16 | Buy |
TRC | C291980 | Chidamide | 250mg | $1320 | 2021-12-16 | Buy |
Properties
Boiling point :602.1±55.0 °C(Predicted)
Density :1.336±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
form :A crystalline solid
pka :12.05±0.70(Predicted)
color :White to off-white
Density :1.336±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
form :A crystalline solid
pka :12.05±0.70(Predicted)
color :White to off-white
Safety Information
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Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Precautionary statements: |
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Description
Chidamide is an inhibitor of histone deacetylases (HDACs; IC50s = 0.095, 0.160, 0.067, 0.733, 0.078, and 0.432 μM for HDAC1-3, 8, 10, and 11, respectively). It is selective for these HDACs over HDAC4-7 and 9 (IC50s = >30 μM for all). Chidamide also inhibits nicotinamide phosphoribosyltransferase (Nampt; IC50 = 2.1 μM). It inhibits cell growth in a panel of 18 cancer cell lines (GI50s = 0.4-40 μM) but has no effect on the growth of non-cancerous CCC-HEK human fetal kidney or CCC-HEL human liver cells (GI50s = >100 μM). In vivo, tucidinostat (12.5, 25, and 50 mg/kg) reduces tumor growth in HCT-8, A549, BEL-7402, and MCF-7 mouse xenograft models.Related product price
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