U0126
|
- $44 - $1802
- Product name: U0126
- CAS: 109511-58-2
- MF: C18H16N6S2
- MW: 380.49
- EINECS:
- MDL Number:MFCD09971039
- Synonyms:U0126;1,4-DIAMINO-2,3-DICYANO-1,4-BIS(2-AMINOPHENYLTHIO)BUTADIENE;1,4-DIAMINO-2,3-DICYANO-1,4-BIS(2-AMINOPHYNYLTIO)BUTADIENE;1,4-DIAMINO-2,3-DICYANO-1,4-BIS(O-AMINOPHENYLMERCAPTO)BUTADIENE;1,4-DIAMINO-2,3-DICYANO-1;UO 126;U0126 >99%;2,3-Bis[amino[(2-aminophenyl)thio]methylene]butanedinitrile
38 prices
Selected condition：
Brand
- AK Scientific
- Alfa Aesar
- Apolloscientific
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 5mg
- 5
- 1mg
- 25
- 10mg
- 20mg
- 25mg
- 50mg
- 100mg
- 250mg
- 300mg
- 1g
- 1000mg
- ManufacturerAK Scientific
- Product numberV2422
- Product description1,4-Diamino-2,3-dicyano-1,4-bis(o-aminophenylmercapto)butadiene
- Packaging5mg
- Price$229
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ61246
- Product descriptionU0126, 99+%
- Packaging25mg
- Price$196
- Updated2023-06-20
- Buy
- ManufacturerAlfa Aesar
- Product numberJ61246
- Product descriptionU0126, 99+%
- Packaging100mg
- Price$349
- Updated2023-06-20
- Buy
- ManufacturerAlfa Aesar
- Product numberJ61246
- Product descriptionU0126, 99+%
- Packaging300mg
- Price$637
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIU1095
- Product descriptionU0126 >99%
- Packaging5mg
- Price$109
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIU1095
- Product descriptionU0126 >99%
- Packaging10mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIU1095
- Product descriptionU0126 >99%
- Packaging25mg
- Price$283
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2520
- Product descriptionU0126-U126 99%
- Packaging50mg
- Price$341
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546009
- Product descriptionU0126 >98%
- Packaging5mg
- Price$226.1
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546009
- Product descriptionU0126 >98%
- Packaging25mg
- Price$372.3
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180969
- Product descriptionU0126 >98%
- Packaging100mg
- Price$606.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180969
- Product descriptionU0126 >98%
- Packaging250mg
- Price$912.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180969
- Product descriptionU0126 >98%
- Packaging1000mg
- Price$1802
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB137489
- Product descriptionU 0126
- Packaging10mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB137489
- Product descriptionU 0126
- Packaging50mg
- Price$262.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number70970
- Product descriptionU-0126 ≥98%
- Packaging1mg
- Price$44
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | V2422 | 1,4-Diamino-2,3-dicyano-1,4-bis(o-aminophenylmercapto)butadiene | 5mg | $229 | 2021-12-16 | Buy |
| Alfa Aesar | J61246 | U0126, 99+% | 25mg | $196 | 2023-06-20 | Buy |
| Alfa Aesar | J61246 | U0126, 99+% | 100mg | $349 | 2023-06-20 | Buy |
| Alfa Aesar | J61246 | U0126, 99+% | 300mg | $637 | 2021-12-16 | Buy |
| Apolloscientific | BIU1095 | U0126 >99% | 5mg | $109 | 2021-12-16 | Buy |
| Apolloscientific | BIU1095 | U0126 >99% | 10mg | $160 | 2021-12-16 | Buy |
| Apolloscientific | BIU1095 | U0126 >99% | 25mg | $283 | 2021-12-16 | Buy |
| Axon Medchem | Axon2520 | U0126-U126 99% | 50mg | $341 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546009 | U0126 >98% | 5mg | $226.1 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546009 | U0126 >98% | 25mg | $372.3 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180969 | U0126 >98% | 100mg | $606.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180969 | U0126 >98% | 250mg | $912.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180969 | U0126 >98% | 1000mg | $1802 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB137489 | U 0126 | 10mg | $75 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB137489 | U 0126 | 50mg | $262.5 | 2021-12-16 | Buy |
| Cayman Chemical | 70970 | U-0126 ≥98% | 1mg | $44 | 2024-03-01 | Buy |
Properties
Melting point :approximate 154℃(dec.)
Boiling point :565.1±50.0 °C(Predicted)
Density :1.44
RTECS :EJ9710000
storage temp. :Desiccate at +4°C
solubility :Soluble in DMSO (up to 200 mg/ml).
form :White solid
pka :2.11±0.10(Predicted)
color :White
Water Solubility :Soluble in DMSO. Poorly soluble in ethanol and water
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Boiling point :565.1±50.0 °C(Predicted)
Density :1.44
RTECS :EJ9710000
storage temp. :Desiccate at +4°C
solubility :Soluble in DMSO (up to 200 mg/ml).
form :White solid
pka :2.11±0.10(Predicted)
color :White
Water Solubility :Soluble in DMSO. Poorly soluble in ethanol and water
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
U-0126 is a selective MAP Kinase Kinase (MKK, MEK) inhibitor with IC50 values of 72 nM and 58 nM for MEK1 and MEK2, respectively. It shows little to no inhibition against a number of other kinases including PKC, Ab1, Raf, MEKK, ERK, JNK, MKK-3, MKK-4, MKK-6, Cdk2, and Cdk4. U-0126 inhibition of MEK is noncompetitive with respect adenosine triphosphate (ATP) and its phosphorylation target ERK, which may partially explain its selectivity profile against other kinases.Related product price
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