UCPH-101
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- $50 - $1950
- Product name: UCPH-101
- CAS: 1118460-77-7
- MF: C27H22N2O3
- MW: 422.48
- EINECS:
- MDL Number:
- Synonyms:UCPH-101;2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile;4H-1-Benzopyran-3-carbonitrile, 2-aMino-5,6,7,8-tetrahydro-4-(4-Methoxyphenyl)-7-(1-naphthalenyl)-5-oxo-;2-Amino-4-(4-methoxy-phenyl)-7-naphthalen-1-yl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile;UCPH-101; UCPH 101; UCPH101;CS-2757;2-amino-4-(4-methoxyphenyl)-7-(naphthalene-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile;inhibit,UCPH101,UCPH-101,Inhibitor
22 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- Cayman Chemical
- Crysdot
- DC Chemicals
- Tocris
- TRC
Package
- 10
- 1mg
- 500μg
- 50
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number4503DC
- Product description2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-YL)-5-oxo-4H-chromene-3-carbonitrile
- Packaging1mg
- Price$225
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA673822
- Product descriptionUCPH-101 97%
- Packaging5mg
- Price$272
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA673822
- Product descriptionUCPH-101 97%
- Packaging10mg
- Price$380
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA673822
- Product descriptionUCPH-101 97%
- Packaging25mg
- Price$646
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA673822
- Product descriptionUCPH-101 97%
- Packaging100mg
- Price$1426
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0009873
- Product description2-AMINO-5,6,7,8-TETRAHYDRO-4-(4-METHOXYPHENYL)-7-(1-NAPHTHALENYL)-5-OXO-4H-1-BENZOPYRAN-3-CARBONITRILE 95.00%
- Packaging5MG
- Price$501.69
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21460
- Product descriptionUCPH-101 ≥98%
- Packaging500μg
- Price$62
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21460
- Product descriptionUCPH-101 ≥98%
- Packaging1mg
- Price$115
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21460
- Product descriptionUCPH-101 ≥98%
- Packaging5mg
- Price$477
- Updated2024-03-01
- Buy
- ManufacturerCrysdot
- Product numberCD31004950
- Product descriptionUCPH-101 97%
- Packaging100mg
- Price$1823
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004950
- Product descriptionUCPH-101 97%
- Packaging50mg
- Price$958
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004950
- Product descriptionUCPH-101 97%
- Packaging25mg
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004950
- Product descriptionUCPH-101 97%
- Packaging10mg
- Price$278
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004950
- Product descriptionUCPH-101 97%
- Packaging5mg
- Price$161
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004950
- Product descriptionUCPH-101 97%
- Packaging2mg
- Price$89
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004950
- Product descriptionUCPH-101 97%
- Packaging1mg
- Price$50
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 4503DC | 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-YL)-5-oxo-4H-chromene-3-carbonitrile | 1mg | $225 | 2021-12-16 | Buy |
| Ambeed | A673822 | UCPH-101 97% | 5mg | $272 | 2021-12-16 | Buy |
| Ambeed | A673822 | UCPH-101 97% | 10mg | $380 | 2021-12-16 | Buy |
| Ambeed | A673822 | UCPH-101 97% | 25mg | $646 | 2021-12-16 | Buy |
| Ambeed | A673822 | UCPH-101 97% | 100mg | $1426 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0009873 | 2-AMINO-5,6,7,8-TETRAHYDRO-4-(4-METHOXYPHENYL)-7-(1-NAPHTHALENYL)-5-OXO-4H-1-BENZOPYRAN-3-CARBONITRILE 95.00% | 5MG | $501.69 | 2021-12-16 | Buy |
| Cayman Chemical | 21460 | UCPH-101 ≥98% | 500μg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 21460 | UCPH-101 ≥98% | 1mg | $115 | 2024-03-01 | Buy |
| Cayman Chemical | 21460 | UCPH-101 ≥98% | 5mg | $477 | 2024-03-01 | Buy |
| Crysdot | CD31004950 | UCPH-101 97% | 100mg | $1823 | 2021-12-16 | Buy |
| Crysdot | CD31004950 | UCPH-101 97% | 50mg | $958 | 2021-12-16 | Buy |
| Crysdot | CD31004950 | UCPH-101 97% | 25mg | $500 | 2021-12-16 | Buy |
| Crysdot | CD31004950 | UCPH-101 97% | 10mg | $278 | 2021-12-16 | Buy |
| Crysdot | CD31004950 | UCPH-101 97% | 5mg | $161 | 2021-12-16 | Buy |
| Crysdot | CD31004950 | UCPH-101 97% | 2mg | $89 | 2021-12-16 | Buy |
| Crysdot | CD31004950 | UCPH-101 97% | 1mg | $50 | 2021-12-16 | Buy |
Properties
Melting point :194.0-197.2 °C
Boiling point :703.5±60.0 °C(Predicted)
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :Soluble in DMSO (up to 10 mg/ml).
form :solid
pka :3.23±0.60(Predicted)
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Boiling point :703.5±60.0 °C(Predicted)
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :Soluble in DMSO (up to 10 mg/ml).
form :solid
pka :3.23±0.60(Predicted)
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
UCPH-101 is a noncompetitive inhibitor of excitatory amino acid transporter 1 (EAAT1), which takes up extracellular glutamate in the central nervous system. UCPH-1 is selective for EAAT1 over EAAT2 and EAAT3 with IC50 values of 0.66, >300, and >300 μM, respectively, in a radioligand uptake assay using HEK293 cells transfected with the human transporter. It selectively inhibits anion currents in tsA201 cells expressing human EAAT1 (Kd = 0.34 μM) over rat EAAT4 and mouse EAAT5 at concentrations up to 10 μM. UCPH-101 is orally bioavailable in rats at a dose of 10 mg/kg but does not cross the blood-brain barrier.Related product price
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