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ChemicalBook >> CAS DataBase List >> Ulixertinib hydrochloride

Ulixertinib hydrochloride

Ulixertinib hydrochloride price.
  • $29 - $455
  • Product name: Ulixertinib hydrochloride
  • CAS: 1956366-10-1
  • MF: C21H23Cl3N4O2
  • MW: 469.79192
  • EINECS:-0
  • MDL Number:
  • Synonyms:BVD523;(S)-4-(5-chloro-2-(isopropylamino)pyridin-4-yl)-N-(1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamidehydrochloride;Ulixertinib hydrochloride;Ulixertinib HCl salt;Ulixertinib HCl;Ulixertinib hydrochloride (BVD-523 hydrochloride;VRT752271 hydrochloride);Ulixertinib hydrochloride (Synonyms: BVD-523 hydrochloride
15 prices
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Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number9445DU
  • Product descriptionUlixertinibhydrochloride
  • Packaging10mg
  • Price$455
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3921
  • Product descriptionUlixertinib(hydrochloride)
  • Packaging5mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3921
  • Product descriptionUlixertinib(hydrochloride)
  • Packaging10mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3921
  • Product descriptionUlixertinib(hydrochloride)
  • Packaging25mg
  • Price$320
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18298
  • Product descriptionUlixertinib (hydrochloride) ≥98%
  • Packaging25mg
  • Price$141
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18298
  • Product descriptionUlixertinib (hydrochloride) ≥98%
  • Packaging10mg
  • Price$99
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18298
  • Product descriptionUlixertinib (hydrochloride) ≥98%
  • Packaging5mg
  • Price$64
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18298
  • Product descriptionUlixertinib (hydrochloride) ≥98%
  • Packaging1mg
  • Price$29
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0093706
  • Product descriptionUlixertinib(hydrochloride) 99.95%
  • Packaging100mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0093706
  • Product descriptionUlixertinib(hydrochloride) 99.95%
  • Packaging50mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0093706
  • Product descriptionUlixertinib(hydrochloride) 99.95%
  • Packaging10mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0093706
  • Product descriptionUlixertinib(hydrochloride) 99.95%
  • Packaging5mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11172477
  • Product descriptionUlixertinibhydrochloride 97%
  • Packaging50mg
  • Price$216
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberU700835
  • Product descriptionUlixertinibHydrochloride
  • Packaging250mg
  • Price$345
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number468445
  • Product descriptionUlixertinib Hydrochloride
  • Packaging100mg
  • Price$446
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9445DU Ulixertinibhydrochloride 10mg $455 2021-12-16 Buy
ApexBio Technology C3921 Ulixertinib(hydrochloride) 5mg $90 2021-12-16 Buy
ApexBio Technology C3921 Ulixertinib(hydrochloride) 10mg $160 2021-12-16 Buy
ApexBio Technology C3921 Ulixertinib(hydrochloride) 25mg $320 2021-12-16 Buy
Cayman Chemical 18298 Ulixertinib (hydrochloride) ≥98% 25mg $141 2024-03-01 Buy
Cayman Chemical 18298 Ulixertinib (hydrochloride) ≥98% 10mg $99 2024-03-01 Buy
Cayman Chemical 18298 Ulixertinib (hydrochloride) ≥98% 5mg $64 2024-03-01 Buy
Cayman Chemical 18298 Ulixertinib (hydrochloride) ≥98% 1mg $29 2024-03-01 Buy
ChemScene CS-0093706 Ulixertinib(hydrochloride) 99.95% 100mg $450 2021-12-16 Buy
ChemScene CS-0093706 Ulixertinib(hydrochloride) 99.95% 50mg $250 2021-12-16 Buy
ChemScene CS-0093706 Ulixertinib(hydrochloride) 99.95% 10mg $110 2021-12-16 Buy
ChemScene CS-0093706 Ulixertinib(hydrochloride) 99.95% 5mg $70 2021-12-16 Buy
Crysdot CD11172477 Ulixertinibhydrochloride 97% 50mg $216 2021-12-16 Buy
TRC U700835 UlixertinibHydrochloride 250mg $345 2021-12-16 Buy
Usbiological 468445 Ulixertinib Hydrochloride 100mg $446 2021-12-16 Buy

Properties

Melting point :231-232°C
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
color :White to Off-White
InChIKey :DKGYQCPFBWFTHM-JHTMQSDJNA-N
SMILES :O=C(N[C@H](CO)C1C=C(Cl)C=CC=1)C1NC=C(C2C(Cl)=CN=C(NC(C)C)C=2)C=1.Cl |&1:3,r|

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Ulixertinib is a reversible ERK1/2 inhibitor that demonstrates an IC50 value of <0.3 nM for ERK2. In A375 melanoma cells with b-RafV600E mutation, it has been reported to reduce the levels of phosphorylated ERK2 and the downstream kinase RSK (IC50s = 4.1 and 0.14 μM, respectively). Ulixertinib has also been shown to inhibit A375 cell proliferation with an IC50 value of 180 nM.