VICRIVIROC MALEATE
- $86 - $13604.85
- Product name: VICRIVIROC MALEATE
- CAS: 599179-03-0
- MF: C32H42F3N5O6
- MW: 649.7009896
- EINECS:
- MDL Number:MFCD09833218
- Synonyms:Vicriviroc Maleate(SCH 417690);(4,6-diMethylpyriMidin-5-yl)(4-((S)-4-((R)-2-Methoxy-1-(4-(trifluoroMethyl)phenyl)ethyl)-3-Methylpiperazin-1-yl)-4-Methylpiperidin-1-yl)Methanone fuMarate;vicriviroc Maleate salt;1-[(4,6-Dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methylpiperidine (2Z)-2-butenedioate VicrivirocMalate;Vicriviroc maleate 1-[(4,6-Dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methylpiperidine (2Z)-2-butenedioate;SCH-D;VICRIVIROC MALEATE;VICRIVIROC MALEATE: SCH-D
11 prices
Selected condition:
Brand
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
Package
- 1mg
- 5mg
- 10mg
- 1g
- 5G
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0005096
- Product descriptionVICRIVIROC MALEATE 95.00%
- Packaging5G
- Price$13604.85
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3916
- Product description(4,6-dimethylpyrimidin-5-yl)(4-(4-(2-methoxy-1-(4-(trifluoromethyl)phenyl)ethyl)-3-methylpiperazin-1-yl)-4-methylpiperidin-1-yl)methanone fumarate
- Packaging5mg
- Price$307
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number28453
- Product descriptionVicriviroc (maleate)
- Packaging1mg
- Price$86
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28453
- Product descriptionVicriviroc (maleate)
- Packaging5mg
- Price$274
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28453
- Product descriptionVicriviroc (maleate)
- Packaging10mg
- Price$421
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-1019
- Product descriptionVicriviroc(maleate) 99.91%
- Packaging5mg
- Price$330
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31001343
- Product descriptionVicrivirocmaleate 98+%
- Packaging5mg
- Price$179
- Updated2021-12-16
- Buy
- ManufacturerCSNpharm
- Product numberCSN12197
- Product descriptionVicrivirocMaleate
- Packaging5mg
- Price$281
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC7336
- Product descriptionVicrivirocmaleate(Sch-417690) >98%
- Packaging1g
- Price$2800
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML2768
- Product descriptionVicriviroc Maleate ≥98% (HPLC)
- Packaging1MG
- Price$94.2
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML2768
- Product descriptionVicriviroc Maleate ≥98% (HPLC)
- Packaging5MG
- Price$381
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
American Custom Chemicals Corporation | API0005096 | VICRIVIROC MALEATE 95.00% | 5G | $13604.85 | 2021-12-16 | Buy |
ApexBio Technology | A3916 | (4,6-dimethylpyrimidin-5-yl)(4-(4-(2-methoxy-1-(4-(trifluoromethyl)phenyl)ethyl)-3-methylpiperazin-1-yl)-4-methylpiperidin-1-yl)methanone fumarate | 5mg | $307 | 2021-12-16 | Buy |
Cayman Chemical | 28453 | Vicriviroc (maleate) | 1mg | $86 | 2024-03-01 | Buy |
Cayman Chemical | 28453 | Vicriviroc (maleate) | 5mg | $274 | 2024-03-01 | Buy |
Cayman Chemical | 28453 | Vicriviroc (maleate) | 10mg | $421 | 2024-03-01 | Buy |
ChemScene | CS-1019 | Vicriviroc(maleate) 99.91% | 5mg | $330 | 2021-12-16 | Buy |
Crysdot | CD31001343 | Vicrivirocmaleate 98+% | 5mg | $179 | 2021-12-16 | Buy |
CSNpharm | CSN12197 | VicrivirocMaleate | 5mg | $281 | 2021-12-16 | Buy |
DC Chemicals | DC7336 | Vicrivirocmaleate(Sch-417690) >98% | 1g | $2800 | 2021-12-16 | Buy |
Sigma-Aldrich | SML2768 | Vicriviroc Maleate ≥98% (HPLC) | 1MG | $94.2 | 2024-03-01 | Buy |
Sigma-Aldrich | SML2768 | Vicriviroc Maleate ≥98% (HPLC) | 5MG | $381 | 2024-03-01 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMSO : 50 mg/mL (76.96 mM; Need ultrasonic)H2O : 25 mg/mL (38.48 mM; Need ultrasonic and warming)
form :Powder
color :White to off-white
solubility :DMSO : 50 mg/mL (76.96 mM; Need ultrasonic)H2O : 25 mg/mL (38.48 mM; Need ultrasonic and warming)
form :Powder
color :White to off-white
Safety Information
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Signal word: | Warning | ||||||||||||||||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
Vicriviroc is a chemokine (C-C motif) receptor 5 (CCR5) antagonist (Ki = 2.5 nM). It selectively inhibits CCR5 over M1 and M2 muscarinic acetylcholine receptors (Kis = >10,000 nM for both) and human-ether-a-go-go (hERG) potassium channels (IC50 = 5.8 μM). Vicriviroc decreases chemotaxis induced by chemokine (C-C motif) ligand 3 (CCL3) in Ba/F3 cells expressing recombinant human CCR5 with an IC50 value of 0.91 nM. It inhibits the replication of 30 R5-tropic HIV-1 clinical isolates in peripheral blood mononuclear cells (PBMCs; EC50s = 0.04-1.4 nM) and reduces viral entry of seven drug-resistant strains of HIV-1 in U87 cells expressing CD4 and CCR5 (EC50s = 8.7-32.9 nM).Related product price
- Vicriviroc Malate
$307-8853.08 - 2-Amino-4,6-dimethylpyrimidine
$5-860 - 2,6-Lutidine
$9.9-9735.6
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