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ChemicalBook >> CAS DataBase List >> Wnt Agonist

Wnt Agonist

Wnt Agonist price.
  • $70 - $6980
  • Product name: Wnt Agonist
  • CAS: 853220-52-7
  • MF: C19H18N4O3
  • MW: 350.37
  • EINECS:
  • MDL Number:MFCD09908087
  • Synonyms:AMBMP;CID 11210285 hydrochloride;N4-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-2,4-pyrimidinediamine hydrochloride;Wnt agonist 1;BML-284;2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine hydrochloride;Wnt agonist 1 (BML-284);N4-(1,3-Benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-2,4-pyrimidinediamine
24 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • JR MediChem
  • Sigma-Aldrich
Package
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 1g
  • 5g
  • ManufacturerAK Scientific
  • Product number5764CS
  • Product descriptionWntAgonist
  • Packaging5mg
  • Price$201
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number5764CS
  • Product descriptionWntAgonist
  • Packaging50mg
  • Price$606
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004755
  • Product descriptionN4-(1,3-BENZODIOXOL-5-YLMETHYL)-6-(3-METHOXYPHENYL)-2,4-PYRIMIDINEDIAMINE HYDROCHLORIDE 95.00%
  • Packaging5MG
  • Price$501.51
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6059
  • Product descriptionWntagonist1
  • Packaging200mg
  • Price$554
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19903
  • Product descriptionWnt Agonist I ≥98%
  • Packaging5mg
  • Price$93
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19903
  • Product descriptionWnt Agonist I ≥98%
  • Packaging10mg
  • Price$120
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19903
  • Product descriptionWnt Agonist I ≥98%
  • Packaging25mg
  • Price$275
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19903
  • Product descriptionWnt Agonist I ≥98%
  • Packaging50mg
  • Price$456
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM255315
  • Product descriptionN4-(Benzo[d][1,3]dioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine 98%
  • Packaging250mg
  • Price$727
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5516
  • Product descriptionBML-284 99.98%
  • Packaging5mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5516
  • Product descriptionBML-284 99.98%
  • Packaging10mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5516
  • Product descriptionBML-284 99.98%
  • Packaging50mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5516
  • Product descriptionBML-284 99.98%
  • Packaging100mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5516
  • Product descriptionBML-284 99.98%
  • Packaging200mg
  • Price$810
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000596
  • Product descriptionBML-284 98+%
  • Packaging50mg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000596
  • Product descriptionBML-284 98+%
  • Packaging100mg
  • Price$441
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 5764CS WntAgonist 5mg $201 2021-12-16 Buy
AK Scientific 5764CS WntAgonist 50mg $606 2021-12-16 Buy
American Custom Chemicals Corporation INB0004755 N4-(1,3-BENZODIOXOL-5-YLMETHYL)-6-(3-METHOXYPHENYL)-2,4-PYRIMIDINEDIAMINE HYDROCHLORIDE 95.00% 5MG $501.51 2021-12-16 Buy
ApexBio Technology B6059 Wntagonist1 200mg $554 2021-12-16 Buy
Cayman Chemical 19903 Wnt Agonist I ≥98% 5mg $93 2024-03-01 Buy
Cayman Chemical 19903 Wnt Agonist I ≥98% 10mg $120 2024-03-01 Buy
Cayman Chemical 19903 Wnt Agonist I ≥98% 25mg $275 2024-03-01 Buy
Cayman Chemical 19903 Wnt Agonist I ≥98% 50mg $456 2024-03-01 Buy
Chemenu CM255315 N4-(Benzo[d][1,3]dioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine 98% 250mg $727 2021-12-16 Buy
ChemScene CS-5516 BML-284 99.98% 5mg $70 2021-12-16 Buy
ChemScene CS-5516 BML-284 99.98% 10mg $100 2021-12-16 Buy
ChemScene CS-5516 BML-284 99.98% 50mg $350 2021-12-16 Buy
ChemScene CS-5516 BML-284 99.98% 100mg $550 2021-12-16 Buy
ChemScene CS-5516 BML-284 99.98% 200mg $810 2021-12-16 Buy
Crysdot CD31000596 BML-284 98+% 50mg $280 2021-12-16 Buy
Crysdot CD31000596 BML-284 98+% 100mg $441 2021-12-16 Buy

Properties

Boiling point :623.4±65.0 °C(Predicted)
Density :1.353±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
pka :6.62±0.10(Predicted)
form :Yellowish sticky solid
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Wnt Agonist is a cell-permeable pyrimidine compound that acts as, at an IC50 > 60 μM, a potent and selective activator of Wnt signaling. In addition to mimicking the effect of Wnt, Wnt Agonist has also induced β-catenin and T-cell fate-dependent transcriptional activity in HEK-293T cells at an EC50 = 700 nM. When applied to Xenopous embryos Wnt Agonist caused substantial head defects development. Wnt Agonist has also been observed to enhance beta cell expansion in vitro. The compound is beneficial for studying the effects of Wnt pathway due to the activation of Wnt without inhibiting the activity of GSK-3β.

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