Welcome to chemicalbook!
China English Japan Germany
400-158-6606
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
Structure Search
Inquriy
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
My chemicalbook My chemicalbook

Welcome back!

RFQ
skype
MY Account
Top
ChemicalBook >> CAS DataBase List >> XL765

XL765

XL765 price.
  • $31 - $1725
  • Product name: XL765
  • CAS: 1349796-36-6
  • MF: C31H29N5O6S
  • MW: 599.66
  • EINECS:
  • MDL Number:MFCD18252649
  • Synonyms:SAR245409 (XL765);PI3K-IN-1;N-[4-[[[3-[(3,5-Dimethoxyphenyl)amino]-2-quinoxalinyl]amino]sulfonyl]phenyl]-3-methoxy-4-methylbenzamide;Benzamide, N-[4-[[[3-[(3,5-dimethoxyphenyl)amino]-2-quinoxalinyl]amino]sulfonyl]phenyl]-3-methoxy-4-methyl-;Voxtalisib (SAR245409, XL765);N-[4-[[[3-[(3,5-Dimethoxyphenyl)amino]-2-quinoxalinyl]amino]sulfonyl]phenyl]-3-methoxy-4-methylbenzamide SAR245409 (XL765);XL765 N-[4-[[[3-[(3,5-Dimethoxyphenyl)amino]-2-quinoxalinyl]amino]sulfonyl]phenyl]-3-methoxy-4-methylbenzamide;N-(4-(N-(3-((3,5-Dimethoxyphenyl)amino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylben
Price30 Properties Safety Information Description
30 prices
Selected condition：
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 10mM(in 1mL DMSO)
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1137-M001
  • Product descriptionXL765 ≥95%
  • Packaging1mg
  • Price$135
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1137-M005
  • Product descriptionXL765 ≥95%
  • Packaging5mg
  • Price$227
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1137-M010
  • Product descriptionXL765 ≥95%
  • Packaging10mg
  • Price$346
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN1137
  • Product descriptionXL765
  • Packaging50mg
  • Price$1065
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN1137
  • Product descriptionXL765
  • Packaging100mg
  • Price$1725
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA781923
  • Product descriptionXL765Analogue 98+%
  • Packaging2mg
  • Price$31
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA781923
  • Product descriptionXL765Analogue 98+%
  • Packaging10mg
  • Price$68
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA781923
  • Product descriptionXL765Analogue 98+%
  • Packaging50mg
  • Price$198
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA781923
  • Product descriptionXL765Analogue 98+%
  • Packaging100mg
  • Price$258
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5634
  • Product descriptionSAR245409(XL765)
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5634
  • Product descriptionSAR245409(XL765)
  • Packaging10mM(in 1mL DMSO)
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5634
  • Product descriptionSAR245409(XL765)
  • Packaging25mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5634
  • Product descriptionSAR245409(XL765)
  • Packaging100mg
  • Price$980
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16299
  • Product descriptionXL765 ≥95%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16299
  • Product descriptionXL765 ≥95%
  • Packaging5mg
  • Price$193
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16299
  • Product descriptionXL765 ≥95%
  • Packaging10mg
  • Price$363
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences SYN-1137-M001 XL765 ≥95% 1mg $135 2021-12-16 Buy
Adipogen Life Sciences SYN-1137-M005 XL765 ≥95% 5mg $227 2021-12-16 Buy
Adipogen Life Sciences SYN-1137-M010 XL765 ≥95% 10mg $346 2021-12-16 Buy
AK Scientific SYN1137 XL765 50mg $1065 2021-12-16 Buy
AK Scientific SYN1137 XL765 100mg $1725 2021-12-16 Buy
Ambeed A781923 XL765Analogue 98+% 2mg $31 2021-12-16 Buy
Ambeed A781923 XL765Analogue 98+% 10mg $68 2021-12-16 Buy
Ambeed A781923 XL765Analogue 98+% 50mg $198 2021-12-16 Buy
Ambeed A781923 XL765Analogue 98+% 100mg $258 2021-12-16 Buy
ApexBio Technology A5634 SAR245409(XL765) 5mg $120 2021-12-16 Buy
ApexBio Technology A5634 SAR245409(XL765) 10mM(in 1mL DMSO) $150 2021-12-16 Buy
ApexBio Technology A5634 SAR245409(XL765) 25mg $350 2021-12-16 Buy
ApexBio Technology A5634 SAR245409(XL765) 100mg $980 2021-12-16 Buy
Cayman Chemical 16299 XL765 ≥95% 1mg $44 2024-03-01 Buy
Cayman Chemical 16299 XL765 ≥95% 5mg $193 2024-03-01 Buy
Cayman Chemical 16299 XL765 ≥95% 10mg $363 2024-03-01 Buy
Next Last

Properties

Density :1.387±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in H2O; insoluble in EtOH; ≥15 mg/mL in DMSO
form :solid
pka :5.88±0.30(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Phosphatidylinositol 3-kinase (PI3K) and the mammalian target of rapamycin (mTOR) constitutively signal and drive cell survival and proliferation in many forms of cancer. XL765 is a dual inhibitor of both PI3K and mTOR, completely blocking phosphorylation of substrates at 8-16 μM. Similarly, XL765 is cytotoxic to glioblastoma multiforme (GBM) xenografts in vitro, with half maximal inhibition occurring at 3.7-7.7 μM. XL765 is orally bioavailable and passes the blood-brain barrier, reducing the growth of intracranial GBM xenografts in mice. This inhibitor is effective alone or in combination therapy with other compounds in various types of cancer.

More related product prices

675576-98-4 LEE011 UMI-77 MK-2206 2HCl Bortezomib

Related product price

Suppliers and manufacturers

career henan chemical co
XL765
$2.00 /1kg
XL765 CAS:1349796-36-6
ATK CHEMICAL COMPANY LIMITED
Biochempartner
BOC Sciences
Chongqing Chemdad Co., Ltd
TargetMol Chemicals Inc.
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
ShenZhen Trendseen Biological Technology Co.,Ltd.