XMU-MP-1
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- $78 - $2000
- Product name: XMU-MP-1
- CAS: 2061980-01-4
- MF: C17H16N6O3S2
- MW: 416.48
- EINECS:
- MDL Number:MFCD30377214
- Synonyms:XMU-MP-1;PubChem ID: 121499143;CS-2590;4-[(6,10-Dihydro-5,10-dimethyl-6-oxo-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide;Benzenesulfonamide, 4-[(6,10-dihydro-5,10-dimethyl-6-oxo-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]-;4-((5,10-dimethyl-6-oxo-6,10-dihydro-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino)benzenesulfonamide;XMU MP 1,Inhibitor,Hippo (MST),inhibit,XMUMP1;XUM-MP- 1
22 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
Package
- 2mg
- 2.5mg
- 10
- 1mg
- 50
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number6147EG
- Product descriptionXmu-MP-1
- Packaging50mg
- Price$687
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8735
- Product descriptionXMU-MP-1
- Packaging25mg
- Price$656
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8735
- Product descriptionXMU-MP-1
- Packaging100mg
- Price$1967
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBX166961
- Product descriptionXMU MP 1
- Packaging10mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBX166961
- Product descriptionXMU MP 1
- Packaging50mg
- Price$472.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number22083
- Product descriptionXMU-MP-1 ≥98%
- Packaging1mg
- Price$78
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22083
- Product descriptionXMU-MP-1 ≥98%
- Packaging5mg
- Price$175
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22083
- Product descriptionXMU-MP-1 ≥98%
- Packaging10mg
- Price$308
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22083
- Product descriptionXMU-MP-1 ≥98%
- Packaging25mg
- Price$670
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-5818
- Product descriptionXMU-MP-1 99.71%
- Packaging2mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5818
- Product descriptionXMU-MP-1 99.71%
- Packaging5mg
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5818
- Product descriptionXMU-MP-1 99.71%
- Packaging10mg
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5818
- Product descriptionXMU-MP-1 99.71%
- Packaging25mg
- Price$390
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5818
- Product descriptionXMU-MP-1 99.71%
- Packaging50mg
- Price$650
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5818
- Product descriptionXMU-MP-1 99.71%
- Packaging100mg
- Price$990
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9926
- Product descriptionXMU-MP-1 >98%
- Packaging250mg
- Price$1000
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 6147EG | Xmu-MP-1 | 50mg | $687 | 2021-12-16 | Buy |
| ApexBio Technology | A8735 | XMU-MP-1 | 25mg | $656 | 2021-12-16 | Buy |
| ApexBio Technology | A8735 | XMU-MP-1 | 100mg | $1967 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BX166961 | XMU MP 1 | 10mg | $135 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BX166961 | XMU MP 1 | 50mg | $472.5 | 2021-12-16 | Buy |
| Cayman Chemical | 22083 | XMU-MP-1 ≥98% | 1mg | $78 | 2024-03-01 | Buy |
| Cayman Chemical | 22083 | XMU-MP-1 ≥98% | 5mg | $175 | 2024-03-01 | Buy |
| Cayman Chemical | 22083 | XMU-MP-1 ≥98% | 10mg | $308 | 2024-03-01 | Buy |
| Cayman Chemical | 22083 | XMU-MP-1 ≥98% | 25mg | $670 | 2024-03-01 | Buy |
| ChemScene | CS-5818 | XMU-MP-1 99.71% | 2mg | $90 | 2021-12-16 | Buy |
| ChemScene | CS-5818 | XMU-MP-1 99.71% | 5mg | $130 | 2021-12-16 | Buy |
| ChemScene | CS-5818 | XMU-MP-1 99.71% | 10mg | $190 | 2021-12-16 | Buy |
| ChemScene | CS-5818 | XMU-MP-1 99.71% | 25mg | $390 | 2021-12-16 | Buy |
| ChemScene | CS-5818 | XMU-MP-1 99.71% | 50mg | $650 | 2021-12-16 | Buy |
| ChemScene | CS-5818 | XMU-MP-1 99.71% | 100mg | $990 | 2021-12-16 | Buy |
| DC Chemicals | DC9926 | XMU-MP-1 >98% | 250mg | $1000 | 2021-12-16 | Buy |
Properties
Boiling point :714.8±70.0 °C(Predicted)
Density :1.523±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :≥41.6 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH
form :powder
pka :9.77±0.12(Predicted)
color :white to beige
Density :1.523±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :≥41.6 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH
form :powder
pka :9.77±0.12(Predicted)
color :white to beige
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
XMU-MP-1 is an inhibitor of the pro-apoptotic, sterile 20-like kinases MST1 and 2 (IC50s = 71.1 and 38.1 nM, respectively). It is selective for MST1 and 2 over a panel of 468 kinases at a concentration of 1 μM. XMU-MP-1 inhibits phosphorylation of MOB1, LATS1 and 2, and YAP in HepG2 cells as well as MST1 and 2 autophosphorylation in RAW 264.7, U2OS, SW480, RPE1, SNU423, and HepG2 cells in a concentration-dependent manner. It also prevents cell death induced by overexpression of MST2. XMU-MP-1 (1 mg/kg) enhances liver regeneration in mice post partial hepatectomy and reduces liver fibrosis in a mouse model of chronic liver injury.Suppliers and manufacturers
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