YM 26734
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- $36 - $1900
- Product name: YM 26734
- CAS: 144337-18-8
- MF: C45H62O8
- MW: 730.97
- EINECS:
- MDL Number:MFCD00918068
- Synonyms:YM 26734;1-Dodecanone, 1,1'-(5-(3,4-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl)-2,4,6-trihydroxy-1,3-phenylene)bis-;4-(3,5-Didodecanoyl-2,4,6-trihydroxyphenyl)-7-hydroxy-2-(4-hydroxyphenyl)chroman;1,1'-[5-[3,4-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl]-2,4,6-trihydroxy-1,3-phenylene]bis-1-dodecanone;1-[3-dodecanoyl-2,4,6-trihydroxy-5-[7-hydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-4-yl]phenyl]dodecan-1-one;1-{3-dodecanoyl-2,4,6-trihydroxy-5-[7-hydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-yl]phenyl}dodecan-1-one
13 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 5mg
- 10
- 1mg
- 10mg
- 25mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product numberSYN5086
- Product descriptionYM-26734
- Packaging10mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001214
- Product descriptionYM 26734 95.00%
- Packaging10MG
- Price$265.65
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17631
- Product descriptionYM-26734 ≥95%
- Packaging1mg
- Price$36
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17631
- Product descriptionYM-26734 ≥95%
- Packaging5mg
- Price$130
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17631
- Product descriptionYM-26734 ≥95%
- Packaging10mg
- Price$239
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17631
- Product descriptionYM-26734 ≥95%
- Packaging25mg
- Price$553
- Updated2024-03-01
- Buy
- ManufacturerDC Chemicals
- Product numberDC43023
- Product descriptionYM-26734 >98%
- Packaging250mg
- Price$950
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC43023
- Product descriptionYM-26734 >98%
- Packaging1g
- Price$1900
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1226
- Product descriptionYM-26734 ≥95% (HPLC)
- Packaging5MG
- Price$146
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1226
- Product descriptionYM-26734 ≥95% (HPLC)
- Packaging25MG
- Price$578
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number2522
- Product descriptionYM26734 ≥95%(HPLC)
- Packaging10
- Price$215
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberY100570
- Product descriptionYM-26734
- Packaging5mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number257148
- Product descriptionYM 26734
- Packaging10mg
- Price$466
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5086 | YM-26734 | 10mg | $150 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001214 | YM 26734 95.00% | 10MG | $265.65 | 2021-12-16 | Buy |
| Cayman Chemical | 17631 | YM-26734 ≥95% | 1mg | $36 | 2024-03-01 | Buy |
| Cayman Chemical | 17631 | YM-26734 ≥95% | 5mg | $130 | 2024-03-01 | Buy |
| Cayman Chemical | 17631 | YM-26734 ≥95% | 10mg | $239 | 2024-03-01 | Buy |
| Cayman Chemical | 17631 | YM-26734 ≥95% | 25mg | $553 | 2024-03-01 | Buy |
| DC Chemicals | DC43023 | YM-26734 >98% | 250mg | $950 | 2021-12-16 | Buy |
| DC Chemicals | DC43023 | YM-26734 >98% | 1g | $1900 | 2021-12-16 | Buy |
| Sigma-Aldrich | SML1226 | YM-26734 ≥95% (HPLC) | 5MG | $146 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML1226 | YM-26734 ≥95% (HPLC) | 25MG | $578 | 2024-03-01 | Buy |
| Tocris | 2522 | YM26734 ≥95%(HPLC) | 10 | $215 | 2021-12-16 | Buy |
| TRC | Y100570 | YM-26734 | 5mg | $85 | 2021-12-16 | Buy |
| Usbiological | 257148 | YM 26734 | 10mg | $466 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :Soluble to 100 mM in DMSO and to 100 mM in ethanol
form :Powder
solubility :Soluble to 100 mM in DMSO and to 100 mM in ethanol
form :Powder
Safety Information
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Description
Secreted phospholipases A2 (sPLA2s) are a diverse family of low molecular weight PLA2s with tissue-specific expression patterns and actions. The group IIA sPLA2 (sPLA2-IIA) was originally purified from platelets and exudates from patients with rheumatoid arthritis. Its expression can be induced by inflammatory mediators, and mouse studies suggest that it may play roles in colorectal polyposis, atherosclerosis, and bacterial infections. YM-26734 is a derivative of a compound isolated from the fruit of H. amygdaline that competitively inhibits rabbit platelet sPLA2 with an IC50 value of 85 nM. It inhibits sPLA2-hGIIA, -mGIIA, -rGIIA, -hGV, -mGV, -hGX, and -mGX with IC50 values of 80, 30, 120, 110, 520, >1600, and >1600 nM, respectively. YM-26734 displays minimal activity at cytosolic PLA2, COX and lipoxygenase. At 45 μg/ear or 11 mg/kg i.v., YM-26734 has been used to ameliorate local inflammatory responses in TPA-induced mouse ear edema.More related product prices
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