Z-AEVD-FMK
|
- $68 - $1025
- Product name: Z-AEVD-FMK
- CAS: 1135688-47-9
- MF: C28H39FN4O10
- MW: 610.63
- EINECS:
- MDL Number:MFCD03453601
- Synonyms:GROUP III CASPASE INHIBITOR I;Z-ALA-GLU(OME)-VAL-ASP(OME)-FLUOROMETHYLKETONE;Z-ALA-GLU(OME)-VAL-ASP(OME)-FMK;Z-AE(OME)VD(OME)-FMK;Z-AE(OME)VD(OME)-FMK (FLUOROMETHYL);Z-AEVD-FMK;CHZRBQFKZDGMTP-CDSYHYPYSA-N;Z-AVED-FMK
7 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
- Medical Isotopes, Inc.
- TRC
Package
- 500μg
- 1mg
- 5mg
- ManufacturerAK Scientific
- Product number2802DC
- Product descriptionMethyl(4S)-5-[[(2S)-1-[[(3S)-5-fluoro-1-methoxy-1,4-dioxopentan-3-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxo-4-[[(2S)-2-(phenylmethoxycarbonylamino)propanoyl]amino]pentanoate
- Packaging1mg
- Price$241
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14987
- Product descriptionZ-AEVD-FMK ≥95%
- Packaging500μg
- Price$68
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14987
- Product descriptionZ-AEVD-FMK ≥95%
- Packaging1mg
- Price$130
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14987
- Product descriptionZ-AEVD-FMK ≥95%
- Packaging5mg
- Price$570
- Updated2024-03-01
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number41443
- Product description(5S,8S,11S,14S)-Methyl14-(2-Fluoroacetyl)-11-isopropyl-8-(3-methoxy-3-oxopropyl)-5-methyl-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oate
- Packaging1mg
- Price$625
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number41443
- Product description(5S,8S,11S,14S)-Methyl14-(2-Fluoroacetyl)-11-isopropyl-8-(3-methoxy-3-oxopropyl)-5-methyl-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oate
- Packaging5mg
- Price$1025
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberM305365
- Product description(5S,8S,11S,14S)-Methyl14-(2-Fluoroacetyl)-11-isopropyl-8-(3-methoxy-3-oxopropyl)-5-methyl-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oate
- Packaging500μg
- Price$70
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2802DC | Methyl(4S)-5-[[(2S)-1-[[(3S)-5-fluoro-1-methoxy-1,4-dioxopentan-3-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxo-4-[[(2S)-2-(phenylmethoxycarbonylamino)propanoyl]amino]pentanoate | 1mg | $241 | 2021-12-16 | Buy |
| Cayman Chemical | 14987 | Z-AEVD-FMK ≥95% | 500μg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 14987 | Z-AEVD-FMK ≥95% | 1mg | $130 | 2024-03-01 | Buy |
| Cayman Chemical | 14987 | Z-AEVD-FMK ≥95% | 5mg | $570 | 2024-03-01 | Buy |
| Medical Isotopes, Inc. | 41443 | (5S,8S,11S,14S)-Methyl14-(2-Fluoroacetyl)-11-isopropyl-8-(3-methoxy-3-oxopropyl)-5-methyl-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oate | 1mg | $625 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 41443 | (5S,8S,11S,14S)-Methyl14-(2-Fluoroacetyl)-11-isopropyl-8-(3-methoxy-3-oxopropyl)-5-methyl-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oate | 5mg | $1025 | 2021-12-16 | Buy |
| TRC | M305365 | (5S,8S,11S,14S)-Methyl14-(2-Fluoroacetyl)-11-isopropyl-8-(3-methoxy-3-oxopropyl)-5-methyl-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oate | 500μg | $70 | 2021-12-16 | Buy |
Properties
Boiling point :883.7±65.0 °C(Predicted)
Density :1.236±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: 10 mg/ml*
form :A crystalline solid
pka :11.12±0.46(Predicted)
color :White to light yellow
Density :1.236±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: 10 mg/ml*
form :A crystalline solid
pka :11.12±0.46(Predicted)
color :White to light yellow
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
Z-AEVD-FMK is an irreversible inhibitor of caspase-10 and related caspases. At 10 μM, it can prevent the initiation of Fas signaling by caspase-10 in Jurkat T lymphoma cells, preventing Bid cleavage into its active form, caspase cascade activation, and apoptosis.Suppliers and manufacturers
BOC Sciences
VDM Biochemicals
Shanghai Harvest Chemical Industrial Co., Ltd.
Alabiotech Inc.
Shanghai Haohong Pharmaceutical Co., Ltd.
Alpha Biopharmaceuticals Co., Ltd
Shanghai Hongye Biotechnology Co. Ltd
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Energy Chemical
Shanghai Yifei Biotechnology Co. , Ltd.