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ChemicalBook >> CAS DataBase List >> AGM-1470

AGM-1470

AGM-1470 price.
  • $61 - $9980
  • Product name: AGM-1470
  • CAS: 129298-91-5
  • MF: C19H28ClNO6
  • MW: 401.88
  • EINECS:
  • MDL Number:MFCD00870281
  • Synonyms:NSC642492;O-(chloroacetylcarbamoyl)fumagillol;O-(CHLOROACETYLCARBAMOYL)FUMAGILLOLTNP-470 AGM-1470;[(3R,4S,5S,6R)-5-Methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl] N-(2-chloroacetyl)carbamate;AGM-1470;Carbamic acid, (chloroacetyl)-, (3R,4S,5S,6R)-5-methoxy-4-[ (2R,3R)-2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]oct-6-yl ester;Tnp-470;N-(2-Chloroacetyl)carbamicacid(3R,4S,5S,6R)-5-Methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]oct-6-ylester
Price20 Properties Safety Information Description
20 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • JR MediChem
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 5mg
  • 10mg
  • 25mg
  • 100mg
  • 500mg
  • 5g
  • 1 mg
  • ManufacturerAK Scientific
  • Product number7768BA
  • Product descriptionO-(Chloroacetylcarbamoyl)fumagillol
  • Packaging10mg
  • Price$302
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0009209
  • Product descriptionTNP-470 95.00%
  • Packaging10MG
  • Price$726.44
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3622
  • Product descriptionTNP-470
  • Packaging5mg
  • Price$104
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3622
  • Product descriptionTNP-470
  • Packaging10mg
  • Price$198
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3622
  • Product descriptionTNP-470
  • Packaging25mg
  • Price$469
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16449
  • Product descriptionTNP-470 ≥98%
  • Packaging1 mg
  • Price$61
  • Updated2023-06-20
  • Buy
  • ManufacturerCayman Chemical
  • Product number16449
  • Product descriptionTNP-470 ≥98%
  • Packaging5mg
  • Price$91
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16449
  • Product descriptionTNP-470 ≥98%
  • Packaging10mg
  • Price$173
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16449
  • Product descriptionTNP-470 ≥98%
  • Packaging25mg
  • Price$410
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-8106
  • Product descriptionTNP-470 >99.0%
  • Packaging5mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-8106
  • Product descriptionTNP-470 >99.0%
  • Packaging10mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerJR MediChem
  • Product numberJR6-L3045
  • Product descriptionTNP-470 96%
  • Packaging5mg
  • Price$68
  • Updated2021-12-16
  • Buy
  • ManufacturerJR MediChem
  • Product numberJR6-L3045
  • Product descriptionTNP-470 96%
  • Packaging25mg
  • Price$198
  • Updated2021-12-16
  • Buy
  • ManufacturerJR MediChem
  • Product numberJR6-L3045
  • Product descriptionTNP-470 96%
  • Packaging500mg
  • Price$1698
  • Updated2021-12-16
  • Buy
  • ManufacturerJR MediChem
  • Product numberJR6-L3045
  • Product descriptionTNP-470 96%
  • Packaging5g
  • Price$9980
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number48973
  • Product descriptionTNP-470
  • Packaging100mg
  • Price$1325
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 7768BA O-(Chloroacetylcarbamoyl)fumagillol 10mg $302 2021-12-16 Buy
American Custom Chemicals Corporation API0009209 TNP-470 95.00% 10MG $726.44 2021-12-16 Buy
ApexBio Technology C3622 TNP-470 5mg $104 2021-12-16 Buy
ApexBio Technology C3622 TNP-470 10mg $198 2021-12-16 Buy
ApexBio Technology C3622 TNP-470 25mg $469 2021-12-16 Buy
Cayman Chemical 16449 TNP-470 ≥98% 1 mg $61 2023-06-20 Buy
Cayman Chemical 16449 TNP-470 ≥98% 5mg $91 2024-03-01 Buy
Cayman Chemical 16449 TNP-470 ≥98% 10mg $173 2024-03-01 Buy
Cayman Chemical 16449 TNP-470 ≥98% 25mg $410 2024-03-01 Buy
ChemScene CS-8106 TNP-470 >99.0% 5mg $180 2021-12-16 Buy
ChemScene CS-8106 TNP-470 >99.0% 10mg $550 2021-12-16 Buy
JR MediChem JR6-L3045 TNP-470 96% 5mg $68 2021-12-16 Buy
JR MediChem JR6-L3045 TNP-470 96% 25mg $198 2021-12-16 Buy
JR MediChem JR6-L3045 TNP-470 96% 500mg $1698 2021-12-16 Buy
JR MediChem JR6-L3045 TNP-470 96% 5g $9980 2021-12-16 Buy
Medical Isotopes, Inc. 48973 TNP-470 100mg $1325 2021-12-16 Buy
Next Last

Properties

Melting point :90-93°C
alpha :D24 -46.6° (c = 0.44 in CHCl3)
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: >15mg/mL
pka :7.19±0.46(Predicted)
form :White to light yellow solid
color :White to Pale Yellow Waxy
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

TNP-470 is a synthetic analog of fumagillin that inhibits angiogenesis. It irreversibly inactivates methionine aminopeptidase-2 (MetAP2; IC50 = 2 μM), blocking endothelial cell proliferation in vitro and angiogenesis in vivo. It is without effect on MetAP1. TNP-470 has therapeutic potential in cancer and microsporidiosis.

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