arglabin
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- $49 - $2200
- Product name: arglabin
- CAS: 84692-91-1
- MF: C15H18O3
- MW: 246.3
- EINECS:
- MDL Number:MFCD11519463
- Synonyms:(3aR,4aS,6aS,9aS,9bR)-5,6,6a,7,9a,9b-Hexahydro-1,4a-dimethyl-7-methylene-3H-oxireno[8,8a]azuleno[4,5-b]furan-8(4aH)-one;arglabin;(3aR,4aS)-1,4aα-Dimethyl-7-methylene-4a,5,6,6aα,9aβ,9bα-hexahydro-3H-oxireno[8,8a]azuleno[4,5-b]furan-8(7H)-one;(3aS)-2,3,3aβ,4,5β,6,6a,7,9aβ,9bα-Decahydro-6α,6aα-epoxy-6,9-dimethyl-3-methyleneazuleno[4,5-b]furan-2-one;3H-Oxireno[8,8a]azuleno[4,5-b]furan-8(4aH)-one, 5,6,6a,7,9a,9b-hexahydro-1,4a-diMethyl-7-Methylene-, [4aS-(3aS*,4aα,6aα,9aβ,9bα)]-;Arglabine;3H-Oxireno[8,8a]azuleno[4,5-b]furan-8(4aH)-one,5,6,6a,7,9a,9b-hexahydro-1,4a-dimethyl-7-methylene-, (3aR,4aS,6aS,9aS,9bR);Arglabin 84692-91-1
19 prices
Selected condition：
Brand
- Adipogen Life Sciences
- Arctom
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 500μg
- 1mg
- 2.5mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0458-M005
- Product descriptionArglabin ≥98%(HPLC)
- Packaging5mg
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN89201
- Product descriptionArglabin
- Packaging5mg
- Price$318
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19502
- Product descriptionArglabin
- Packaging500μg
- Price$49
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19502
- Product descriptionArglabin
- Packaging1mg
- Price$92
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19502
- Product descriptionArglabin
- Packaging5mg
- Price$380
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-3012
- Product descriptionArglabin 99.17%
- Packaging100mg
- Price$1200
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3012
- Product descriptionArglabin 99.17%
- Packaging10mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3012
- Product descriptionArglabin 99.17%
- Packaging25mg
- Price$600
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3012
- Product descriptionArglabin 99.17%
- Packaging50mg
- Price$800
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3012
- Product descriptionArglabin 99.17%
- Packaging5mg
- Price$280
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD32000274
- Product descriptionArglabin 98+%
- Packaging5mg
- Price$228
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD32000274
- Product descriptionArglabin 98+%
- Packaging10mg
- Price$326
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD32000274
- Product descriptionArglabin 98+%
- Packaging50mg
- Price$977
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD32000274
- Product descriptionArglabin 98+%
- Packaging100mg
- Price$1367
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9645
- Product description(+)-Arglabin >98%
- Packaging100mg
- Price$1200
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number63004
- Product descriptionArglabin
- Packaging25mg
- Price$2200
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CN2-0458-M005 | Arglabin ≥98%(HPLC) | 5mg | $300 | 2021-12-16 | Buy |
| Arctom | CFN89201 | Arglabin | 5mg | $318 | 2021-12-16 | Buy |
| Cayman Chemical | 19502 | Arglabin | 500μg | $49 | 2024-03-01 | Buy |
| Cayman Chemical | 19502 | Arglabin | 1mg | $92 | 2024-03-01 | Buy |
| Cayman Chemical | 19502 | Arglabin | 5mg | $380 | 2024-03-01 | Buy |
| ChemScene | CS-3012 | Arglabin 99.17% | 100mg | $1200 | 2021-12-16 | Buy |
| ChemScene | CS-3012 | Arglabin 99.17% | 10mg | $450 | 2021-12-16 | Buy |
| ChemScene | CS-3012 | Arglabin 99.17% | 25mg | $600 | 2021-12-16 | Buy |
| ChemScene | CS-3012 | Arglabin 99.17% | 50mg | $800 | 2021-12-16 | Buy |
| ChemScene | CS-3012 | Arglabin 99.17% | 5mg | $280 | 2021-12-16 | Buy |
| Crysdot | CD32000274 | Arglabin 98+% | 5mg | $228 | 2021-12-16 | Buy |
| Crysdot | CD32000274 | Arglabin 98+% | 10mg | $326 | 2021-12-16 | Buy |
| Crysdot | CD32000274 | Arglabin 98+% | 50mg | $977 | 2021-12-16 | Buy |
| Crysdot | CD32000274 | Arglabin 98+% | 100mg | $1367 | 2021-12-16 | Buy |
| DC Chemicals | DC9645 | (+)-Arglabin >98% | 100mg | $1200 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 63004 | Arglabin | 25mg | $2200 | 2021-12-16 | Buy |
Properties
Melting point :100-102 °C
Boiling point :404.6±45.0 °C(Predicted)
Density :1.22±0.1 g/cm3(Predicted)
storage temp. :Amber Vial, -20°C Freezer, Under inert atmosphere
solubility :Chloroform (Slightly)
form :Solid
color :Off-White
Boiling point :404.6±45.0 °C(Predicted)
Density :1.22±0.1 g/cm3(Predicted)
storage temp. :Amber Vial, -20°C Freezer, Under inert atmosphere
solubility :Chloroform (Slightly)
form :Solid
color :Off-White
Safety Information
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Description
Arglabin is a new antineoplastic agent launched in Russia for the treatment of a variety of cancers. It is a sesquiterpene gamma-lactone extracted from Artemisia glabella, a plant from Kazakstan; it was first developed in Kazakstan followed by US and other countries as an ethical pharmaceutical. Arglabin can be obtained by resin extraction from A.glabella, purification by chromatography and finally recrystallization. Arglabin is a potent and selective inhibitor of farnesyl transferase, an enzyme critical to the function of the Ras oncogene in cancer cell reproduction. It showed a strong Inhibitory effect against tumor cells proliferation in in vitro models of transformed mouse hepatocytes and splenocytes. This cytotoxic effect against tumor cells was 50-100 times higher than that on intact cells. In many patients with various cancers, Arglabin was shown to stop or inhibit the tumour development, alone or in combination with other anticancer agents, and was reportedly well tolerated with few sideeffects. Promising response rates were also reported with Arglabin after treating other 《difficult-to-treat cancers》 such as breast, ovarian, lung or colon cancers.Related product price
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Suppliers and manufacturers
Shanghai Zheyan Biotech Co., Ltd.
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Chengdu Biopurify Phytochemicals Ltd.
Chongqing Chemdad Co., Ltd
SIMAGCHEM CORP
ANHUI WITOP BIOTECH CO., LTD
Zhejiang J&C Biological Technology Co.,Limited
