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ChemicalBook >> CAS DataBase List >> Auranofin

Auranofin

Auranofin price.
  • $45 - $2200
  • Product name: Auranofin
  • CAS: 34031-32-8
  • MF: C20H34AuO9PS
  • MW: 678.48
  • EINECS:251-801-9
  • MDL Number:MFCD00080759
  • Synonyms:gold,(1-thio-beta-d-glucopyranose2,3,4,6-tetraacetato-s)(triethylphosphine) ;ridaura ;sk&f39162 ;sk&f39162d ;sk&fd-39162 ;AURANOFIN;AURANOFINE;Auranon
34 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • AvaChem
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 5mg
  • 10mg
  • 10
  • 2.5mg
  • 50
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3611-M025
  • Product descriptionAuranofin ≥95%
  • Packaging25mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3611-M100
  • Product descriptionAuranofin ≥95%
  • Packaging100mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberV0192
  • Product descriptionAuranofin
  • Packaging1g
  • Price$2027
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA361974
  • Product description((2S,3R,4S,5R,6R)-3,4,5-Triacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-thio)(triethylphosphine)gold 98%
  • Packaging100mg
  • Price$384
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA361974
  • Product description((2S,3R,4S,5R,6R)-3,4,5-Triacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-thio)(triethylphosphine)gold 98%
  • Packaging250mg
  • Price$576
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA361974
  • Product description((2S,3R,4S,5R,6R)-3,4,5-Triacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-thio)(triethylphosphine)gold 98%
  • Packaging1g
  • Price$1440
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0001566
  • Product descriptionAURANOFIN 95.00%
  • Packaging25MG
  • Price$210
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0001566
  • Product descriptionAURANOFIN 95.00%
  • Packaging250MG
  • Price$1963.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7687
  • Product descriptionAuranofin
  • Packaging10mg
  • Price$53
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7687
  • Product descriptionAuranofin
  • Packaging50mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3749
  • Product descriptionAuranofin
  • Packaging5mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3749
  • Product descriptionAuranofin
  • Packaging10mg
  • Price$89
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3749
  • Product descriptionAuranofin
  • Packaging25mg
  • Price$149
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3749
  • Product descriptionAuranofin
  • Packaging100mg
  • Price$289
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMA05382
  • Product descriptionAuranofin
  • Packaging25mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMA05382
  • Product descriptionAuranofin
  • Packaging50mg
  • Price$125
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-3611-M025 Auranofin ≥95% 25mg $45 2021-12-16 Buy
Adipogen Life Sciences AG-CR1-3611-M100 Auranofin ≥95% 100mg $80 2021-12-16 Buy
AK Scientific V0192 Auranofin 1g $2027 2021-12-16 Buy
Ambeed A361974 ((2S,3R,4S,5R,6R)-3,4,5-Triacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-thio)(triethylphosphine)gold 98% 100mg $384 2021-12-16 Buy
Ambeed A361974 ((2S,3R,4S,5R,6R)-3,4,5-Triacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-thio)(triethylphosphine)gold 98% 250mg $576 2021-12-16 Buy
Ambeed A361974 ((2S,3R,4S,5R,6R)-3,4,5-Triacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-thio)(triethylphosphine)gold 98% 1g $1440 2021-12-16 Buy
American Custom Chemicals Corporation API0001566 AURANOFIN 95.00% 25MG $210 2021-12-16 Buy
American Custom Chemicals Corporation API0001566 AURANOFIN 95.00% 250MG $1963.5 2021-12-16 Buy
ApexBio Technology B7687 Auranofin 10mg $53 2021-12-16 Buy
ApexBio Technology B7687 Auranofin 50mg $90 2021-12-16 Buy
AvaChem 3749 Auranofin 5mg $59 2021-12-16 Buy
AvaChem 3749 Auranofin 10mg $89 2021-12-16 Buy
AvaChem 3749 Auranofin 25mg $149 2021-12-16 Buy
AvaChem 3749 Auranofin 100mg $289 2021-12-16 Buy
Biosynth Carbosynth MA05382 Auranofin 25mg $75 2021-12-16 Buy
Biosynth Carbosynth MA05382 Auranofin 50mg $125 2021-12-16 Buy

Properties

Melting point :112-115°
storage temp. :room temp
solubility :DMSO: ≥5mg/mL
form :solid
color :Crystals
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

Auranofin is a gold-thiol complex with anti-inflammatory and immunosuppressive actions. It potently inhibits thioredoxin reductase (IC50 = 0.2 μM), preventing reduction of thioredoxin and altering oxidative signaling relevant to DNA synthesis, transcription, apoptosis, and disease. Auranofin blocks LPS-mediated expression of inflammatory mediators in RAW 264.7 macrophages at 10-20 μM and blocks NF-κB signaling in a stimulus- and cell type-dependent manner. Through these actions, this compound has applications in rheumatoid arthritis and other diseases with an inflammatory component, including cancer. Auranofin also has potential value against certain bacteria, viruses, and parasites.

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