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ChemicalBook >> CAS DataBase List >> CALPAIN INHIBITOR III

CALPAIN INHIBITOR III

CALPAIN INHIBITOR III price.
  • $32 - $695
  • Product name: CALPAIN INHIBITOR III
  • CAS: 88191-84-8
  • MF: C22H26N2O4
  • MW: 382.45
  • EINECS:618-124-4
  • MDL Number:MFCD00798796
  • Synonyms:CALPAIN INHIBITOR III;CARBOBEZOXY-VALINYL-PHENYLALANINALZ-VAL-PHE-CHO;CARBOBENZOXY-VALINYL-PHENYLALANINAL;MDL 28170;Z-VAL-PHE-ALDEHYDE;Z-VAL-PHE-CHO;MDL 28170, Z-Val-Phe-al;Cbz-L-Val-L-Phe-OH
30 prices
Selected condition:
Brand
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • CSNpharm
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Usbiological
Package
  • 10mM(in 1mL DMSO)
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number8910AB
  • Product descriptionCbz-L-Phenylalaninal
  • Packaging10mg
  • Price$164
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ62919
  • Product descriptionCalpain Inhibitor III, 95+%
  • Packaging25mg
  • Price$139
  • Updated2023-06-20
  • Buy
  • ManufacturerAmbeed
  • Product numberA172590
  • Product descriptionBenzyl((2S)-3-methyl-1-oxo-1-((1-oxo-3-phenylpropan-2-yl)amino)butan-2-yl)carbamate 98+%
  • Packaging100mg
  • Price$428
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA172590
  • Product descriptionBenzyl((2S)-3-methyl-1-oxo-1-((1-oxo-3-phenylpropan-2-yl)amino)butan-2-yl)carbamate 98+%
  • Packaging250mg
  • Price$685
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000011
  • Product descriptionCALPAIN INHIBITOR I(III) 95.00%
  • Packaging5MG
  • Price$643.12
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000011
  • Product descriptionCALPAIN INHIBITOR I(III) 95.00%
  • Packaging25MG
  • Price$693.92
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4412
  • Product descriptionMDL 28170
  • Packaging10mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4412
  • Product descriptionMDL 28170
  • Packaging10mM(in 1mL DMSO)
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4412
  • Product descriptionMDL 28170
  • Packaging25mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC29616
  • Product descriptionCalpain Inhibitor III
  • Packaging25mg
  • Price$157.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC29616
  • Product descriptionCalpain Inhibitor III
  • Packaging50mg
  • Price$262.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC29616
  • Product descriptionCalpain Inhibitor III
  • Packaging100mg
  • Price$420
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14283
  • Product descriptionCalpain Inhibitor III ≥95%
  • Packaging5mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14283
  • Product descriptionCalpain Inhibitor III ≥95%
  • Packaging10mg
  • Price$61
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14283
  • Product descriptionCalpain Inhibitor III ≥95%
  • Packaging25mg
  • Price$139
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14283
  • Product descriptionCalpain Inhibitor III ≥95%
  • Packaging50mg
  • Price$243
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8910AB Cbz-L-Phenylalaninal 10mg $164 2021-12-16 Buy
Alfa Aesar J62919 Calpain Inhibitor III, 95+% 25mg $139 2023-06-20 Buy
Ambeed A172590 Benzyl((2S)-3-methyl-1-oxo-1-((1-oxo-3-phenylpropan-2-yl)amino)butan-2-yl)carbamate 98+% 100mg $428 2021-12-16 Buy
Ambeed A172590 Benzyl((2S)-3-methyl-1-oxo-1-((1-oxo-3-phenylpropan-2-yl)amino)butan-2-yl)carbamate 98+% 250mg $685 2021-12-16 Buy
American Custom Chemicals Corporation INB0000011 CALPAIN INHIBITOR I(III) 95.00% 5MG $643.12 2021-12-16 Buy
American Custom Chemicals Corporation INB0000011 CALPAIN INHIBITOR I(III) 95.00% 25MG $693.92 2021-12-16 Buy
ApexBio Technology A4412 MDL 28170 10mg $45 2021-12-16 Buy
ApexBio Technology A4412 MDL 28170 10mM(in 1mL DMSO) $60 2021-12-16 Buy
ApexBio Technology A4412 MDL 28170 25mg $100 2021-12-16 Buy
Biosynth Carbosynth FC29616 Calpain Inhibitor III 25mg $157.5 2021-12-16 Buy
Biosynth Carbosynth FC29616 Calpain Inhibitor III 50mg $262.5 2021-12-16 Buy
Biosynth Carbosynth FC29616 Calpain Inhibitor III 100mg $420 2021-12-16 Buy
Cayman Chemical 14283 Calpain Inhibitor III ≥95% 5mg $32 2024-03-01 Buy
Cayman Chemical 14283 Calpain Inhibitor III ≥95% 10mg $61 2024-03-01 Buy
Cayman Chemical 14283 Calpain Inhibitor III ≥95% 25mg $139 2024-03-01 Buy
Cayman Chemical 14283 Calpain Inhibitor III ≥95% 50mg $243 2024-03-01 Buy

Properties

Boiling point :595.6±50.0 °C(Predicted)
Density :1.153±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 26 mg/mL
form :White lyophilized solid
pka :11.05±0.46(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

Description

The calpains are a family of calcium-dependent cysteine proteases that catalyze limited proteolysis of substrates. Calpain Inhibitor III is a cell permeable, selective inhibitor of μ-calpain (calpain-1) and m-calpain (calpain-2). Calpain Inhibitor III crosses the blood-brain barrier to inhibit brain cysteine protease activity and has been reported to have neuroprotective effects in numerous rodent neurotrauma models, including spinal cord injury, cortical impact trauma, neonatal hypoxia-ischemia, and focal cerebral ischemia. Additionally, Calpain Inhibitor III has been shown to attenuate depression in myocardial contractile performance that occurs during reperfusion following cardiac ischemia.

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