CX-5461
- $28 - $2900
- Product name: CX-5461
- CAS: 1138549-36-6
- MF: C27H27N7O2S
- MW: 513.61
- EINECS:
- MDL Number:MFCD21609261
- Synonyms:CX-5461;2-(4-Methyl-1,4-diazepan-1-yl)-N-((5-Methylpyrazin-2-yl)Methyl)-5-oxo-5H-benzo[4,5]thiazolo[3,2-a][1,8]naphthyridine-6-carboxaMide;RNA Polymerase I Inhibitor II, CX-5461 - CAS 1138549-36-6 - Calbiochem;CS-1938;2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-N-[(5-methyl-2-pyrazinyl)methyl]-5-oxo-5H-benzothiazolo[3,2-a][1,8]naphthyridine-6-carboxamide;CX-5461/CX5461;2-(Hexahydro-4-Methyl-1H-1,4-diazepin-1-yl)-N-[(5-Methyl-2-pyrazinyl)Methyl]-5-oxo-5H-benzothiazolo[3,2-a][1,8]napht;5H-Benzothiazolo[3,2-a][1,8]naphthyridine-6-carboxamide, 2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-N-[(5-methyl-2-pyrazinyl)methyl]-5-oxo-
21 prices
Selected condition:
Brand
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
Package
- 1mg
- 1unit
- 5MG
- 2x5mg
- 10mg
- 50mg
- 100mg
- 250mg
- 5G
- ManufacturerAdipogen Life Sciences
- Product numberSYN-3031-M050
- Product descriptionCX-5461 ≥95%
- Packaging50mg
- Price$853
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN3031
- Product descriptionCX-5461
- Packaging10mg
- Price$270
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001389
- Product descriptionCX-5461 95.00%
- Packaging5MG
- Price$412
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001389
- Product descriptionCX-5461 95.00%
- Packaging5G
- Price$2900
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8337
- Product descriptionCX-5461
- Packaging50mg
- Price$540
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8337
- Product descriptionCX-5461
- Packaging10mg
- Price$170
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8337
- Product descriptionCX-5461
- Packaging5mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8337
- Product descriptionCX-5461
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60086
- Product descriptionCX-5461 ≥98%
- Packaging10mg
- Price$198
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2173
- Product descriptionCX5461 99%
- Packaging2x5mg
- Price$198
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18392
- Product descriptionCX-5461 ≥98%
- Packaging1mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18392
- Product descriptionCX-5461 ≥98%
- Packaging5mg
- Price$161
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18392
- Product descriptionCX-5461 ≥98%
- Packaging10mg
- Price$231
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18392
- Product descriptionCX-5461 ≥98%
- Packaging50mg
- Price$957
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0568
- Product descriptionCX-5461 98.13%
- Packaging5mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0568
- Product descriptionCX-5461 98.13%
- Packaging10mg
- Price$192
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Adipogen Life Sciences | SYN-3031-M050 | CX-5461 ≥95% | 50mg | $853 | 2021-12-16 | Buy |
AK Scientific | SYN3031 | CX-5461 | 10mg | $270 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0001389 | CX-5461 95.00% | 5MG | $412 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0001389 | CX-5461 95.00% | 5G | $2900 | 2021-12-16 | Buy |
ApexBio Technology | A8337 | CX-5461 | 50mg | $540 | 2021-12-16 | Buy |
ApexBio Technology | A8337 | CX-5461 | 10mg | $170 | 2021-12-16 | Buy |
ApexBio Technology | A8337 | CX-5461 | 5mg | $110 | 2021-12-16 | Buy |
ApexBio Technology | A8337 | CX-5461 | 1unit | $28 | 2021-12-16 | Buy |
Arctom | CFN60086 | CX-5461 ≥98% | 10mg | $198 | 2021-12-16 | Buy |
Axon Medchem | Axon2173 | CX5461 99% | 2x5mg | $198 | 2021-12-16 | Buy |
Cayman Chemical | 18392 | CX-5461 ≥98% | 1mg | $44 | 2024-03-01 | Buy |
Cayman Chemical | 18392 | CX-5461 ≥98% | 5mg | $161 | 2024-03-01 | Buy |
Cayman Chemical | 18392 | CX-5461 ≥98% | 10mg | $231 | 2024-03-01 | Buy |
Cayman Chemical | 18392 | CX-5461 ≥98% | 50mg | $957 | 2024-03-01 | Buy |
ChemScene | CS-0568 | CX-5461 98.13% | 5mg | $120 | 2021-12-16 | Buy |
ChemScene | CS-0568 | CX-5461 98.13% | 10mg | $192 | 2021-12-16 | Buy |
Properties
Boiling point :739.9±60.0 °C(Predicted)
Density :1.45
storage temp. :+2C to +8C
solubility :insoluble in H2O; insoluble in EtOH; insoluble in DMSO
form :Light beige powder
pka :8.53±0.20(Predicted)
color :White to yellow
Density :1.45
storage temp. :+2C to +8C
solubility :insoluble in H2O; insoluble in EtOH; insoluble in DMSO
form :Light beige powder
pka :8.53±0.20(Predicted)
color :White to yellow
Safety Information
Symbol(GHS): | ||||||||
---|---|---|---|---|---|---|---|---|
Signal word: | ||||||||
Hazard statements: |
|
|||||||
Precautionary statements: |
|
Description
CX-5461 is an inhibitor of ribosomal RNA (rRNA) synthesis. It selectively inhibits RNA polymerase I-driven transcription of rRNA in HCT-116, A375, and MIA PaCa-2 tumor cells (IC50s = 142, 113, and 54 nM, respectively) without affecting RNA polymerase II (IC50 > 25μM), DNA replication, or protein translation. At 50 mg/kg, CX-5461 demonstrates in vivo antitumor activity against human solid tumors in mouse xenograft models.More related product prices
BEZ235 (NVP-BEZ235, Dactolisib) 252917-06-9 BI 2536 BV6 865362-74-9 BortezomibRelated product price
- BEZ235 (NVP-BEZ235, Dactolisib)
$25-1871.1 - 252917-06-9
$28-4070 - BI 2536
$37-2839
Suppliers and manufacturers
Nanjing ChemLin Chemical Industry Co., Ltd.
ATK CHEMICAL COMPANY LIMITED
Biochempartner
Hubei xin bonus chemical co. LTD
Chongqing Chemdad Co., Ltd
TargetMol Chemicals Inc.
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Dideu Industries Group Limited
Zhejiang J&C Biological Technology Co.,Limited