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ChemicalBook >> CAS DataBase List >> darglitazone

darglitazone

darglitazone price.
  • $32 - $520
  • Product name: darglitazone
  • CAS: 141200-24-0
  • MF: C23H20N2O4S
  • MW: 420.48
  • EINECS:
  • MDL Number:
  • Synonyms:darglitazone;2,4-Thiazolidinedione, 5-[[4-[3-(5-methyl-2-phenyl-4-oxazolyl)-1-oxopropyl]phenyl]methyl]-;5-[[4-[3-(5-methyl-2-phenyl-1,3-oxazol-4-yl)propanoyl]phenyl]methyl]-1,3-thiazolidine-2,4-dione;oral,UCP2,corticosterone,PPAR-γ,CP86325,Darglitazone,Diabetes,CP-86325,Inhibitor,PPAR,inhibit,Peroxisome proliferator-activated receptors,CP 86325,thiazolidinedione
Price11 Properties Safety Information Description
11 prices
Selected condition：
Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerAK Scientific
  • Product number3486CA
  • Product descriptionDarglitazone
  • Packaging1mg
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3486CA
  • Product descriptionDarglitazone
  • Packaging5mg
  • Price$218
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3486CA
  • Product descriptionDarglitazone
  • Packaging10mg
  • Price$302
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4758
  • Product descriptionDarglitazone
  • Packaging5mg
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4758
  • Product descriptionDarglitazone
  • Packaging10mg
  • Price$243
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4758
  • Product descriptionDarglitazone
  • Packaging25mg
  • Price$520
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17681
  • Product descriptionDarglitazone ≥95%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17681
  • Product descriptionDarglitazone ≥95%
  • Packaging5mg
  • Price$109
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17681
  • Product descriptionDarglitazone ≥95%
  • Packaging10mg
  • Price$184
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17681
  • Product descriptionDarglitazone ≥95%
  • Packaging25mg
  • Price$420
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberD193410
  • Product descriptionDarglitazone
  • Packaging5mg
  • Price$95
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3486CA Darglitazone 1mg $133 2021-12-16 Buy
AK Scientific 3486CA Darglitazone 5mg $218 2021-12-16 Buy
AK Scientific 3486CA Darglitazone 10mg $302 2021-12-16 Buy
ApexBio Technology C4758 Darglitazone 5mg $130 2021-12-16 Buy
ApexBio Technology C4758 Darglitazone 10mg $243 2021-12-16 Buy
ApexBio Technology C4758 Darglitazone 25mg $520 2021-12-16 Buy
Cayman Chemical 17681 Darglitazone ≥95% 1mg $32 2024-03-01 Buy
Cayman Chemical 17681 Darglitazone ≥95% 5mg $109 2024-03-01 Buy
Cayman Chemical 17681 Darglitazone ≥95% 10mg $184 2024-03-01 Buy
Cayman Chemical 17681 Darglitazone ≥95% 25mg $420 2024-03-01 Buy
TRC D193410 Darglitazone 5mg $95 2021-12-16 Buy

Properties

Density :1.306±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:20.0(Max Conc. mg/mL);47.56(Max Conc. mM)
DMF:20.0(Max Conc. mg/mL);47.56(Max Conc. mM) form :A crystalline solid
pka :6.22±0.50(Predicted)
color :White to light yellow

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Thiazolidinediones (TZDs) are a group of structurally related peroxisome proliferator-activated receptor γ (PPARγ) agonists with antidiabetic actions in vivo. Darglitazone is a TZD that increases the sensitivity of cells to insulin, stimulating insulin-induced PI3K activity at submicromolar concentrations by increasing the expression of the p85 subunit of PI3K. It increases insulin effectiveness in obese non-insulin-dependent diabetes mellitus subjects. Darglitazone promotes adipocyte differentiation by up-regulating the expression of uncoupling protein-2. Through PPARγ, darglitazone restores acute inflammatory responses to cerebral hypoxia-ischemia and reduces infarct size in diabetic ob/ob mice.

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Suppliers and manufacturers

Hubei Jusheng Technology Co.,Ltd.
TargetMol Chemicals Inc. Shanghai EFE Biological Technology Co., Ltd. ChemeGen(Shanghai) Biotechnology Co.,Ltd. Nanjing Shizhou Biology Technology Co.,Ltd Energy Chemical MedBioPharmaceutical Technology Inc ChengDu SinoStandards Bio-Tech Co.,Ltd. ， Nantong Feiyu Biological Technology CO.,LTD TargetMol Chemicals Inc.