exo-IWR 1
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- $60 - $2000
- Product name: exo-IWR 1
- CAS: 1127442-87-8
- MF: C25H19N3O3
- MW: 409.44
- EINECS:
- MDL Number:MFCD18086912
- Synonyms:4-[(3aR,4R,7S,7aS-rel)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide;exo-IWR 1;IWR-1-exo;rel-4-[(3aR,4R,7S,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-Methano-2H-isoindol-2-yl]-N-8-quinolinylbenzaMide;Benzamide, 4-[(3aR,4R,7S,7aS)-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinyl-, rel-;rel-4-((3aR,4R,7S,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl)-N-(quinolin-8-yl)benzamide;Inhibitor,exoIWR1,inhibit,Wnt,exo IWR 1
25 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Medical Isotopes, Inc.
- Tocris
- TRC
- Usbiological
Package
- 50
- 5MG
- 10mg
- 25mg
- 50mg
- 10
- 100MG
- ManufacturerAK Scientific
- Product number1807AH
- Product descriptionIwr-1-exo
- Packaging10mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number1807AH
- Product descriptionIwr-1-exo
- Packaging50mg
- Price$640
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000753
- Product descriptionIWR-1-EXO 95.00%
- Packaging5MG
- Price$180.4
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000753
- Product descriptionIWR-1-EXO 95.00%
- Packaging10MG
- Price$721.88
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000753
- Product descriptionIWR-1-EXO 95.00%
- Packaging100MG
- Price$1732.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7548
- Product descriptionexo-IWR1
- Packaging10mg
- Price$234
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7548
- Product descriptionexo-IWR1
- Packaging50mg
- Price$990
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFE23213
- Product descriptionexo-IWR-1
- Packaging10mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFE23213
- Product descriptionexo-IWR-1
- Packaging50mg
- Price$437.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13598
- Product descriptionIWR-1-exo ≥98%
- Packaging5mg
- Price$67
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13598
- Product descriptionIWR-1-exo ≥98%
- Packaging10mg
- Price$128
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13598
- Product descriptionIWR-1-exo ≥98%
- Packaging25mg
- Price$297
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13598
- Product descriptionIWR-1-exo ≥98%
- Packaging50mg
- Price$525
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0028662
- Product descriptionexo-IWR-1
- Packaging5mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0028662
- Product descriptionexo-IWR-1
- Packaging10mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0028662
- Product descriptionexo-IWR-1
- Packaging25mg
- Price$220
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 1807AH | Iwr-1-exo | 10mg | $218 | 2021-12-16 | Buy |
| AK Scientific | 1807AH | Iwr-1-exo | 50mg | $640 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000753 | IWR-1-EXO 95.00% | 5MG | $180.4 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000753 | IWR-1-EXO 95.00% | 10MG | $721.88 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000753 | IWR-1-EXO 95.00% | 100MG | $1732.5 | 2021-12-16 | Buy |
| ApexBio Technology | B7548 | exo-IWR1 | 10mg | $234 | 2021-12-16 | Buy |
| ApexBio Technology | B7548 | exo-IWR1 | 50mg | $990 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FE23213 | exo-IWR-1 | 10mg | $125 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FE23213 | exo-IWR-1 | 50mg | $437.5 | 2021-12-16 | Buy |
| Cayman Chemical | 13598 | IWR-1-exo ≥98% | 5mg | $67 | 2024-03-01 | Buy |
| Cayman Chemical | 13598 | IWR-1-exo ≥98% | 10mg | $128 | 2024-03-01 | Buy |
| Cayman Chemical | 13598 | IWR-1-exo ≥98% | 25mg | $297 | 2024-03-01 | Buy |
| Cayman Chemical | 13598 | IWR-1-exo ≥98% | 50mg | $525 | 2024-03-01 | Buy |
| ChemScene | CS-0028662 | exo-IWR-1 | 5mg | $60 | 2021-12-16 | Buy |
| ChemScene | CS-0028662 | exo-IWR-1 | 10mg | $100 | 2021-12-16 | Buy |
| ChemScene | CS-0028662 | exo-IWR-1 | 25mg | $220 | 2021-12-16 | Buy |
Properties
Boiling point :643.9±55.0 °C(Predicted)
Density :1.425±0.06 g/cm3(Predicted)
storage temp. :Store at RT
solubility :Soluble to 100 mM in DMSO
form :Powder
pka :11.88±0.43(Predicted)
color :Light yellow to green yellow
Density :1.425±0.06 g/cm3(Predicted)
storage temp. :Store at RT
solubility :Soluble to 100 mM in DMSO
form :Powder
pka :11.88±0.43(Predicted)
color :Light yellow to green yellow
Safety Information
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Description
Wnt signaling proteins are small secreted proteins that are active in embryonic development, tissue homeostasis, and tumorigenesis. Wnt proteins bind to receptors on the cell surface, initiating a signaling cascade that leads to β-catenin activation of gene transcription. IWR-1-exo is a diastereomer of IWR-1-endo, the potent inhibitor of the Wnt response. Whereas IWR-1-endo strongly blocks cell-based Wnt/β-catenin pathway reporter response (IC50 = 180 nM) and suppresses Wnt-dependent zebrafish tail fin regeneration (0.5 μM), IWR-1-exo has little effect in either assay at 10 μM. Thus, this compound is an ideal control for tests involving the active form, IWR-1-endo.Suppliers and manufacturers
TargetMol Chemicals Inc.
InvivoChem
Aladdin Scientific
Amadis Chemical Company Limited
J & K SCIENTIFIC LTD.
3B Pharmachem (Wuhan) International Co.,Ltd.
Chemsky (shanghai) International Co.,Ltd
EMMX Biotechnology LLC
Tianjin Kailiqi Biotechnology Co., Ltd.
Shenzhen Polymeri Biochemical Technology Co., Ltd.