isatidine
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- $468 - $2200
- Product name: isatidine
- CAS: 15503-86-3
- MF: C18H25NO7
- MW: 367.39
- EINECS:
- MDL Number:MFCD00074872
- Synonyms:isatidine;RETRORSINE-N-OXIDE;12,18-Dihydroxy-11,16-dioxosenecionane 4-oxide;12,18-Dihydroxysenecionane-11,16-dione 4-oxide;Retrorsin-N-oxid;[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-(hydroxymethyl)-5-methyl-, 12-oxide, (3Z,5R,6S,14aR,14bR)-
4 prices
Selected condition：
Brand
- Arctom
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 5mg
- 10MG
- 25mg
- ManufacturerArctom
- Product numberCFN00408
- Product descriptionIsatidine ≥98%
- Packaging5mg
- Price$468
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number48572
- Product descriptionRetrorsineN-Oxide
- Packaging25mg
- Price$2200
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberPHL82630
- Product descriptionRetrorsine N-oxide phyproof? Reference Substance
- Packaging10MG
- Price$629
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberR279005
- Product descriptionRetrorsineN-Oxide
- Packaging25mg
- Price$1135
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Arctom | CFN00408 | Isatidine ≥98% | 5mg | $468 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 48572 | RetrorsineN-Oxide | 25mg | $2200 | 2021-12-16 | Buy |
| Sigma-Aldrich | PHL82630 | Retrorsine N-oxide phyproof? Reference Substance | 10MG | $629 | 2024-03-01 | Buy |
| TRC | R279005 | RetrorsineN-Oxide | 25mg | $1135 | 2021-12-16 | Buy |
Properties
Melting point :145°C
Boiling point :497.95°C (rough estimate)
Density :1.3204 (rough estimate)
refractive index :1.5100 (estimate)
pka :11.96±0.40(Predicted)
IARC :3 (Vol. 10, Sup 7) 1987
EPA Substance Registry System :Isatidine (15503-86-3)
Boiling point :497.95°C (rough estimate)
Density :1.3204 (rough estimate)
refractive index :1.5100 (estimate)
pka :11.96±0.40(Predicted)
IARC :3 (Vol. 10, Sup 7) 1987
EPA Substance Registry System :Isatidine (15503-86-3)
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | |||||||||||||||||||||
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Description
This hepatotoxic alkaloid occurs in certain Senecio species and was first isolated from S. isatideus D.C. It occurs abundantly in S. retrorsus D.C. and S. scleratus Schw. The alkaloid crystallizes in rhombic prisms as the dihydrate and has [α]27D . 8.25° (H 20). It is soluble in MeOH, hot EtOH and hot H20 but virtually insoluble in Et 20, Me2CO or CHCl 3. On reduction it absorbs 4 molecules of H2 to give hexahydrodeoxyisatidine which melts at l15-l20°C and then remelts at l83-4°C following an intermediate solidification. This compound gives a hydrochloride, m.p. 218°C (dec.); [α]20D - 52.5° (H20) and may be hydrolyzed with Ba(OHh to give a basic product, tetrahydroisatinecine, CSH1703N, m.p. l74.5°C; [α]20D - 88° (H 20). The alkaloid itself, on hydrolysis with Ba(OHh yields isatinecine and two acid products, isatinecic acid and the monolactone, the latter almost certainly being formed by the action of the base upon the acid.Related product price
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