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ChemicalBook >> CAS DataBase List >> KIFUNENSINE

KIFUNENSINE

KIFUNENSINE price.
  • $50 - $1047
  • Product name: KIFUNENSINE
  • CAS: 109944-15-2
  • MF: C8H12N2O6
  • MW: 232.19
  • EINECS:
  • MDL Number:MFCD00270017
  • Synonyms:KIFUNENSINE, KITASATOSPORIA KIFUNENSE;Imidazo1,2-apyridine-2,3-dione, hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-, (5R,6R,7S,8R,8aS)-;FR 900494, Hexahydro-6R,7S,8aS-trihydroxy-5R-(hydroxymethyl)-imidazo[1,2-a] pyridine-2,3-dione;(5R,8aS)-1,5,6,7,8,8a-Hexahydro-6β,7α,8α-trihydroxy-5α-(hydroxymethyl)imidazo[1,2-a]pyridine-2,3-dione;(5R,6R,7S,8R,8aS)-Hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-imidazo[1,2-a]pyridine-2,3-dione;[5R-(5α,6β,7α,8α,8aα)]-;Kifunensine min. 99%;FR 900494
27 prices
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Brand
  • ApexBio Technology
  • Apolloscientific
  • Axon Medchem
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 1
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • ManufacturerApexBio Technology
  • Product numberB7315
  • Product descriptionKifunensine
  • Packaging1mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBICL4125
  • Product descriptionKifunensine 99% min
  • Packaging1mg
  • Price$218
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBICL4125
  • Product descriptionKifunensine 99%min
  • Packaging5mg
  • Price$322
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBICL4125
  • Product descriptionKifunensine 99%min
  • Packaging10mg
  • Price$517
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBICL4125
  • Product descriptionKifunensine 99%min
  • Packaging25mg
  • Price$1047
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1730
  • Product description(+)-Kifunensine-FR900494 99%
  • Packaging2mg
  • Price$132
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMK10316
  • Product descriptionKifunensine
  • Packaging2mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMK10316
  • Product descriptionKifunensine
  • Packaging5mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMK10316
  • Product descriptionKifunensine
  • Packaging10mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBK164600
  • Product descriptionKifunensine
  • Packaging10mg
  • Price$171
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMK10316
  • Product descriptionKifunensine
  • Packaging25mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMK10316
  • Product descriptionKifunensine
  • Packaging50mg
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBK164600
  • Product descriptionKifunensine
  • Packaging50mg
  • Price$621
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10009437
  • Product descriptionKifunensine ≥98%
  • Packaging1mg
  • Price$65
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10009437
  • Product descriptionKifunensine ≥98%
  • Packaging5mg
  • Price$179
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10009437
  • Product descriptionKifunensine ≥98%
  • Packaging10mg
  • Price$260
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ApexBio Technology B7315 Kifunensine 1mg $110 2021-12-16 Buy
Apolloscientific BICL4125 Kifunensine 99% min 1mg $218 2021-12-16 Buy
Apolloscientific BICL4125 Kifunensine 99%min 5mg $322 2021-12-16 Buy
Apolloscientific BICL4125 Kifunensine 99%min 10mg $517 2021-12-16 Buy
Apolloscientific BICL4125 Kifunensine 99%min 25mg $1047 2021-12-16 Buy
Axon Medchem Axon1730 (+)-Kifunensine-FR900494 99% 2mg $132 2021-12-16 Buy
Biosynth Carbosynth MK10316 Kifunensine 2mg $50 2021-12-16 Buy
Biosynth Carbosynth MK10316 Kifunensine 5mg $100 2021-12-16 Buy
Biosynth Carbosynth MK10316 Kifunensine 10mg $150 2021-12-16 Buy
Biosynth Carbosynth BK164600 Kifunensine 10mg $171 2021-12-16 Buy
Biosynth Carbosynth MK10316 Kifunensine 25mg $300 2021-12-16 Buy
Biosynth Carbosynth MK10316 Kifunensine 50mg $500 2021-12-16 Buy
Biosynth Carbosynth BK164600 Kifunensine 50mg $621 2021-12-16 Buy
Cayman Chemical 10009437 Kifunensine ≥98% 1mg $65 2024-03-01 Buy
Cayman Chemical 10009437 Kifunensine ≥98% 5mg $179 2024-03-01 Buy
Cayman Chemical 10009437 Kifunensine ≥98% 10mg $260 2024-03-01 Buy

Properties

Melting point :>280°C
Density :1.85±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :water, double-distilled: soluble50MM
form :White solid
pka :9.61±0.70(Predicted)
color :White
Water Solubility :Soluble to 5 mM in water with sonication
Stability :Desiccate and Store at -20°C

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Kifunensine is an immunoactive compound originally produced by Kitasatosporia kifunense, which displays competitive inhibition against immunosuppressive factor in tumor-bearing mice. Kifunensine has also been shown to be a potent inhibitor of the purified glycoprotein processing enzyme, mannosidase I (MAN1), specifically MAN1A1, MAN1A2, MAN1B1 and MAN1C1. Enzymes of this class are important factors for the biosynthesis of various types of N-linked oligosaccharide structures. Inhibition of these structures by kifunensine can interfere with cell-to-cell adhesion, targeting of lysosomal hydrolases to lysosomes, and clearance of asialoglycoproteins from the serum.

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