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ChemicalBook >> CAS DataBase List >> macbecin I

macbecin I

macbecin I price.
  • $291 - $1928.08
  • Product name: macbecin I
  • CAS: 73341-72-7
  • MF: C30H42N2O8
  • MW: 558.67
  • EINECS:
  • MDL Number:
  • Synonyms:macbecin I;(6S,15R)-6,17-Didemethoxy-15-methoxy-6-methyl-11-O-methylgeldanamycin;(15R)-6,17-Didemethoxy-15-methoxy-6-methyl-11-O-methyl-geldanamycin;Geldanamycin, 6,17-didemethoxy-15-methoxy-6-methyl-11-O-methyl-, (15R)-;Macbecin
Price8 Properties Safety Information Description
8 prices
Selected condition：
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 1mg
  • 1
  • 0.5mg
  • 1G
  • 2.5G
  • 5G
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008044
  • Product descriptionMACBECIN I 95.00%
  • Packaging1G
  • Price$983.52
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008044
  • Product descriptionMACBECIN I 95.00%
  • Packaging2.5G
  • Price$1473.14
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008044
  • Product descriptionMACBECIN I 95.00%
  • Packaging5G
  • Price$1928.08
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7259
  • Product descriptionMacbecinI
  • Packaging1mg
  • Price$465
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number22225
  • Product descriptionMacbecin I ≥95%
  • Packaging1mg
  • Price$291
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number3061
  • Product descriptionMacbecinI
  • Packaging1
  • Price$311
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberM107525
  • Product descriptionMacbecinI
  • Packaging0.5mg
  • Price$1200
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number255749
  • Product descriptionMacbecin I
  • Packaging1mg
  • Price$573
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0008044 MACBECIN I 95.00% 1G $983.52 2021-12-16 Buy
American Custom Chemicals Corporation API0008044 MACBECIN I 95.00% 2.5G $1473.14 2021-12-16 Buy
American Custom Chemicals Corporation API0008044 MACBECIN I 95.00% 5G $1928.08 2021-12-16 Buy
ApexBio Technology B7259 MacbecinI 1mg $465 2021-12-16 Buy
Cayman Chemical 22225 Macbecin I ≥95% 1mg $291 2024-03-01 Buy
Tocris 3061 MacbecinI 1 $311 2021-12-16 Buy
TRC M107525 MacbecinI 0.5mg $1200 2021-12-16 Buy
Usbiological 255749 Macbecin I 1mg $573 2021-12-16 Buy

Properties

Melting point :205-206 °C(Solv: ethanol (64-17-5); water (7732-18-5))
Boiling point :736.2±60.0 °C(Predicted)
Density :1.17±0.1 g/cm3(Predicted)
storage temp. :Desiccate at -20°C
solubility :Soluble in DMSO > 10 mM
form :Powder
pka :8.62±0.70(Predicted)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Macbecin I is an ansamycin antibiotic compound that inhibits Hsp90 activity (IC50 = 2 μM) by binding to the ATP-binding site. Macbecin I exhibits antitumor and cytocidal activities (IC50 ~ 0.4 μM) by causing degradation of key oncogenic client proteins such as ErbB2 and cRaf1. Macbecin I displays higher potency and affinity than geldanamycin.

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Suppliers and manufacturers

TargetMol Chemicals Inc. 3B Pharmachem (Wuhan) International Co.,Ltd. EMMX Biotechnology LLC ChemeGen(Shanghai) Biotechnology Co.,Ltd. MedBioPharmaceutical Technology Inc TargetMol Chemicals Inc. Shanghai Yifei Biotechnology Co. , Ltd. ApexBio Technology