Moxonidine
|
- $40 - $5000
- Product name: Moxonidine
- CAS: 75438-57-2
- MF: C9H12ClN5O
- MW: 241.68
- EINECS:629-833-3
- MDL Number:MFCD06795643
- Synonyms:MOXONIDINE;MOXONIDINE HCL;4-chloro-n-(4,5-dihydro-1h-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamin ;bdf5895 ;be5895 ;BDF-5895 HCL;4-CHLORO-6-METHOXY-2-METHYL-5-(2-IMIDAZOLIN-2-YL)AMINOPYRIMIDINE HCL;4-CHLORO-N-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)-6-METHOXY-2-METHYL-5-PYRIMIDINAMINE HYDROCHLORIDE
36 prices
Selected condition：
Brand
- AK Scientific
- Alichem
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- TRC
Package
- 1mg
- 5MG
- 10mg
- 25mg
- 50mg
- 200MG
- 250mg
- 100mg
- y0000226
- 1g
- 10mM(in 1mL DMSO)
- 500mg
- 2g
- 5G
- 10g
- 25g
- ManufacturerAK Scientific
- Product numberK289
- Product descriptionMoxonidine
- Packaging500mg
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number75438572
- Product description4-Chloro-n-(4,5-dihydro-1h-imidazol-2-yl)-6-methoxy-2-methylpyrimidin-5-amine
- Packaging250mg
- Price$286.2
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number75438572
- Product description4-Chloro-n-(4,5-dihydro-1h-imidazol-2-yl)-6-methoxy-2-methylpyrimidin-5-amine
- Packaging1g
- Price$688.48
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberRDL0006957
- Product descriptionMOXONIDINE-D3 95.00%
- Packaging5MG
- Price$501.45
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4080
- Product descriptionMoxonidine
- Packaging10mM(in 1mL DMSO)
- Price$42
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS573190
- Product descriptionMoxonidine ≥98%
- Packaging100mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS573190
- Product descriptionMoxonidine ≥98%
- Packaging250mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS573190
- Product descriptionMoxonidine ≥98%
- Packaging1g
- Price$199
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1660B
- Product descriptionMoxonidine
- Packaging10mg
- Price$69
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1660B
- Product descriptionMoxonidine
- Packaging25mg
- Price$119
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1660B
- Product descriptionMoxonidine
- Packaging100mg
- Price$339
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1660B
- Product descriptionMoxonidine
- Packaging1g
- Price$790
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134636
- Product descriptionMoxonidine >99%
- Packaging100mg
- Price$510
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134636
- Product descriptionMoxonidine >99%
- Packaging250mg
- Price$765
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134636
- Product descriptionMoxonidine >99%
- Packaging1g
- Price$1504.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFM165499
- Product descriptionMoxonidine
- Packaging1g
- Price$1000
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | K289 | Moxonidine | 500mg | $220 | 2021-12-16 | Buy |
| Alichem | 75438572 | 4-Chloro-n-(4,5-dihydro-1h-imidazol-2-yl)-6-methoxy-2-methylpyrimidin-5-amine | 250mg | $286.2 | 2021-12-16 | Buy |
| Alichem | 75438572 | 4-Chloro-n-(4,5-dihydro-1h-imidazol-2-yl)-6-methoxy-2-methylpyrimidin-5-amine | 1g | $688.48 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | RDL0006957 | MOXONIDINE-D3 95.00% | 5MG | $501.45 | 2021-12-16 | Buy |
| ApexBio Technology | A4080 | Moxonidine | 10mM(in 1mL DMSO) | $42 | 2021-12-16 | Buy |
| Arctom | AS573190 | Moxonidine ≥98% | 100mg | $50 | 2021-12-16 | Buy |
| Arctom | AS573190 | Moxonidine ≥98% | 250mg | $75 | 2021-12-16 | Buy |
| Arctom | AS573190 | Moxonidine ≥98% | 1g | $199 | 2021-12-16 | Buy |
| AvaChem | 1660B | Moxonidine | 10mg | $69 | 2021-12-16 | Buy |
| AvaChem | 1660B | Moxonidine | 25mg | $119 | 2021-12-16 | Buy |
| AvaChem | 1660B | Moxonidine | 100mg | $339 | 2021-12-16 | Buy |
| AvaChem | 1660B | Moxonidine | 1g | $790 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb134636 | Moxonidine >99% | 100mg | $510 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb134636 | Moxonidine >99% | 250mg | $765 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb134636 | Moxonidine >99% | 1g | $1504.5 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FM165499 | Moxonidine | 1g | $1000 | 2021-12-16 | Buy |
Properties
Melting point :217-219° (dec)
Boiling point :364.7±52.0 °C(Predicted)
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Very slightly soluble in water, sparingly soluble in methanol, slightly soluble in methylene chloride, very slightly soluble in acetonitrile.
form :Solid
pka :7.11±0.10(Predicted)
color :White to Almost white
Water Solubility :800.3mg/L(temperature not stated)
Merck :14,6293
InChIKey :WPNJAUFVNXKLIM-UHFFFAOYSA-N
CAS DataBase Reference :75438-57-2(CAS DataBase Reference)
Boiling point :364.7±52.0 °C(Predicted)
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Very slightly soluble in water, sparingly soluble in methanol, slightly soluble in methylene chloride, very slightly soluble in acetonitrile.
form :Solid
pka :7.11±0.10(Predicted)
color :White to Almost white
Water Solubility :800.3mg/L(temperature not stated)
Merck :14,6293
InChIKey :WPNJAUFVNXKLIM-UHFFFAOYSA-N
CAS DataBase Reference :75438-57-2(CAS DataBase Reference)
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | |||||||||||||||||||||
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Description
Moxonidine, also known as Physiotens, is a highly selective imidazoline receptor agonist-Ⅰ by excitement ventrolateral medulla nucleus (RVLM)-Ⅰ type imidazoline receptor in the peripheral sympathetic nerve activity decreased. This receptor subtype is found in both the rostral ventro-lateral pressor and ventromedial depressor areas of the medulla oblongata.Moxonidine therefore causes a decrease in sympathetic nervous system activity and, therefore, a decrease in blood pressure.
It is a new type of antihypertensive drug, commonly used in the treatment of essential hypertension. Compared to the older central-acting antihypertensives, moxonidine binds with much greater affinity to the imidazoline I1-receptor than to the α2-receptor. In contrast, clonidine binds to both receptors with equal affinity.
It may have a role when thiazides, beta-blockers, ACE inhibitors and calcium channel blockers are not appropriate or have failed to control blood pressure.
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