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ChemicalBook >> CAS DataBase List >> PRIMA-1

PRIMA-1

PRIMA-1 price.
  • $19 - $2325
  • Product name: PRIMA-1
  • CAS: 5608-24-2
  • MF: C9H15NO3
  • MW: 185.22
  • EINECS:
  • MDL Number:MFCD19199989
  • Synonyms:PRIMA-1;P53 REACTIVATION AND INDUCTION OF MASSIVE APOPTOSIS;2,2-BIS(HYDROXYMETHYL)-1-AZABICYCLO[2,2,2]OCTAN-3-ONE;2,2-BIS(HYDROXYMETHYL)-3-QUINUCLIDINONE;2,2-dimethylolquinuclidin-3-one;7,7-bis(hydroxymethyl)-1-azabicyclo[2.2.2]octan-8-one;PRIMA-1 - CAS 5608-24-2 - Calbiochem;2-Bis(hydroxymethyl)-3-quinuclidinone
Price34 Properties Safety Information Description
34 prices
Selected condition：
Brand
  • AHH
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 1mg
  • 10
  • 1unit
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 50
  • 1g
  • 10mM(in 1mL DMSO)
  • ManufacturerAHH
  • Product numberAPI-1964
  • Product descriptionPRIMA-1 Prima-1
  • Packaging1g
  • Price$1200
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1997AH
  • Product description2,2-Bis(hydroxymethyl)-3-quinuclidinone
  • Packaging5mg
  • Price$124
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ64071
  • Product descriptionPRIMA-1
  • Packaging10mg
  • Price$219.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA755385
  • Product descriptionPRIMA-1 98%
  • Packaging5mg
  • Price$51
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA755385
  • Product descriptionPRIMA-1 98%
  • Packaging10mg
  • Price$77
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA755385
  • Product descriptionPRIMA-1 98%
  • Packaging25mg
  • Price$134
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA755385
  • Product descriptionPRIMA-1 98%
  • Packaging50mg
  • Price$173
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA755385
  • Product descriptionPRIMA-1 98%
  • Packaging100mg
  • Price$224
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA755385
  • Product descriptionPRIMA-1 98%
  • Packaging1g
  • Price$2325
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4483
  • Product descriptionPRIMA-1
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4483
  • Product descriptionPRIMA-1
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4483
  • Product descriptionPRIMA-1
  • Packaging5mg
  • Price$56
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4483
  • Product descriptionPRIMA-1
  • Packaging10mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4483
  • Product descriptionPRIMA-1
  • Packaging50mg
  • Price$245
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS658179
  • Product descriptionPRIMA-1 98%
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number63520
  • Product descriptionPRIMA-1 ≥95%
  • Packaging1mg
  • Price$19
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH API-1964 PRIMA-1 Prima-1 1g $1200 2021-12-16 Buy
AK Scientific 1997AH 2,2-Bis(hydroxymethyl)-3-quinuclidinone 5mg $124 2021-12-16 Buy
Alfa Aesar J64071 PRIMA-1 10mg $219.65 2024-03-01 Buy
Ambeed A755385 PRIMA-1 98% 5mg $51 2021-12-16 Buy
Ambeed A755385 PRIMA-1 98% 10mg $77 2021-12-16 Buy
Ambeed A755385 PRIMA-1 98% 25mg $134 2021-12-16 Buy
Ambeed A755385 PRIMA-1 98% 50mg $173 2021-12-16 Buy
Ambeed A755385 PRIMA-1 98% 100mg $224 2021-12-16 Buy
Ambeed A755385 PRIMA-1 98% 1g $2325 2021-12-16 Buy
ApexBio Technology A4483 PRIMA-1 1unit $28 2021-12-16 Buy
ApexBio Technology A4483 PRIMA-1 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ApexBio Technology A4483 PRIMA-1 5mg $56 2021-12-16 Buy
ApexBio Technology A4483 PRIMA-1 10mg $75 2021-12-16 Buy
ApexBio Technology A4483 PRIMA-1 50mg $245 2021-12-16 Buy
Arctom AS658179 PRIMA-1 98% 5mg $50 2021-12-16 Buy
Cayman Chemical 63520 PRIMA-1 ≥95% 1mg $19 2024-03-01 Buy
Next Last

Properties

Melting point :146-147 °C
Boiling point :353.7±17.0 °C(Predicted)
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,2-8°C
solubility :H2O: >10mg/mL
pka :13.68±0.10(Predicted)
form :solid
color :white to off-white
Water Solubility :Soluble in water at 10mg/ml
Sensitive :Light Sensitive

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
Precautionary statements:

Description

Mutations in the p53 tumor suppressor are found in many different neoplastic cells. PRIMA-1 restores sequence-specific DNA binding and transactivational activity to mutant p53 proteins at relatively high μM to mM concentrations. It is therefore a unique anti-oncogenic substance, working as a re-activator of the apoptotic function of mutant p53 via conformational modulation of function-specific epitopes. PRIMA-1 represents a novel lead compound which may be further modified to provide more potent therapeutic agents acting via the reactivation mechanism.

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Suppliers and manufacturers

ATK CHEMICAL COMPANY LIMITED
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
TargetMol Chemicals Inc.
Shanghai Acmec Biochemical Technology Co., Ltd.
Aladdin Scientific
Wuhan Jingkang en Biomedical Technology Co., Ltd Shanghai Boyle Chemical Co., Ltd. Shanghai Boyle Chemical Co., Ltd. 3B Pharmachem (Wuhan) International Co.,Ltd.