viridicatumtoxin
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- $190 - $1161
- Product name: viridicatumtoxin
- CAS: 39277-41-3
- MF: C30H31NO10
- MW: 565.57
- EINECS:
- MDL Number:MFCD01675248
- Synonyms:viridicatumtoxin;NSC 159628;Spiro[2-cyclohexene-1,2'(1'H)-cyclopenta[de]naphthacene]-9'-carboxamide, 7',7'a,8',11',11'a,12'-hexahydro-5',6',7'a,10',11'a,12'-hexahydroxy-3'-methoxy-2,6,6-trimethyl-7',8'-dioxo-, (1R,7'aR,11'aR,12'R)-rel-(-)-
6 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
- TRC
Package
- 1mg
- 5mg
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0172-M001
- Product descriptionViridicatumtoxin ≥95%(HPLC)
- Packaging1mg
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2060DM
- Product descriptionViridicatumtoxin
- Packaging5mg
- Price$1161
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberBIO0000728
- Product descriptionVIRIDICATUMTOXIN 95.00%
- Packaging5MG
- Price$504.9
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number25480
- Product descriptionViridicatumtoxin ≥98%
- Packaging1mg
- Price$227
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number25480
- Product descriptionViridicatumtoxin ≥98%
- Packaging5mg
- Price$954
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberV673905
- Product descriptionViridicatumtoxin
- Packaging1mg
- Price$230
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CN2-0172-M001 | Viridicatumtoxin ≥95%(HPLC) | 1mg | $190 | 2021-12-16 | Buy |
| AK Scientific | 2060DM | Viridicatumtoxin | 5mg | $1161 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | BIO0000728 | VIRIDICATUMTOXIN 95.00% | 5MG | $504.9 | 2021-12-16 | Buy |
| Cayman Chemical | 25480 | Viridicatumtoxin ≥98% | 1mg | $227 | 2024-03-01 | Buy |
| Cayman Chemical | 25480 | Viridicatumtoxin ≥98% | 5mg | $954 | 2024-03-01 | Buy |
| TRC | V673905 | Viridicatumtoxin | 1mg | $230 | 2021-12-16 | Buy |
Properties
Melting point :235°C (rough estimate)
Boiling point :630.75°C (rough estimate)
Density :1.3203 (rough estimate)
refractive index :1.6310 (estimate)
storage temp. :Store at -20°C
solubility :DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form :A solid
Boiling point :630.75°C (rough estimate)
Density :1.3203 (rough estimate)
refractive index :1.6310 (estimate)
storage temp. :Store at -20°C
solubility :DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form :A solid
Safety Information
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| Signal word: | Danger | ||||||||||||||||
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Description
Viridicatumtoxin in a mycotoxin originally isolated from Penicillium that has diverse biological activities, including antimicrobial, cytotoxic, and toxic properties. It inhibits the growth of B. subtilis, M. luteus, C. perfringens, B. fragilis, and methicillin-resistant S. aureus (MRSA; MICs = 0.39-1.56 μg/ml), as well as C. albicans, S. cerevisiae, M. racemosus, A. niger, and P. chrysogenum (MICs = 6.2-25 μg/ml), but has no activity against M. smegmatis, E. coli, K. pneumoniae, P. aeruginosa, or S. marcescens (MICs = >100 μg/ml). Viridicatumtoxin inhibits the production of polyprenyl alcohols by S. aureus undecaprenyl pyrophosphate (UPP) synthase, E. coli octaprenyl pyrophosphate synthase (OPS), and S. cerevisiae dehydrodolichyl pyrophosphate (DedoIPP) synthase in vitro (IC50s = 3.1, 21, and 71 μM, respectively). It has cytotoxic effects against human Jurkat T (IC50 = 4.92 μM), chronic lymphocytic leukemia (CLL; LC50 = 0.7-3.5 nM), and bone marrow-derived HS-5 stromal cells. Viridicatumtoxin is toxic to rats and mice when administered intraperitoneally (LD50s = 80 and 90 mg/kg, respectively) and to rats when administered via gastric intubation (LD50 = 122.4 mg/kg), but not to rats or mice when administered orally or through subcutaneous injection.Related product price
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