[[2,2′-(1,2-Dimethyl-1,2-ethanediylidene)bis[N-methylhydrazinecarbothioamidato]]] copper
2物価
選択条件:
ブランド
- Sigma-Aldrich Japan
パッケージ
- 5mg
- 25mg
- 生産者Sigma-Aldrich Japan
- 製品番号SML0769
- 製品説明 ≥98% (HPLC)
- 英語製品説明Cu-ASTM ≥98% (HPLC)
- 包装単位5mg
- 価格¥21300
- 更新しました2024-03-01
- 購入
- 生産者Sigma-Aldrich Japan
- 製品番号SML0769
- 製品説明 ≥98% (HPLC)
- 英語製品説明Cu-ASTM ≥98% (HPLC)
- 包装単位25mg
- 価格¥80100
- 更新しました2024-03-01
- 購入
生産者 | 製品番号 | 製品説明 | 包装単位 | 価格 | 更新時間 | 購入 |
---|---|---|---|---|---|---|
Sigma-Aldrich Japan | SML0769 | ≥98% (HPLC) Cu-ASTM ≥98% (HPLC) |
5mg | ¥21300 | 2024-03-01 | 購入 |
Sigma-Aldrich Japan | SML0769 | ≥98% (HPLC) Cu-ASTM ≥98% (HPLC) |
25mg | ¥80100 | 2024-03-01 | 購入 |
プロパティ
貯蔵温度 :2-8°C
溶解性 :DMSO: soluble10mg/mL, clear
外見 :powder
色 :brown to dark red-brown
溶解性 :DMSO: soluble10mg/mL, clear
外見 :powder
色 :brown to dark red-brown
安全情報
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説明
The metallo-protein Cu/Zn-superoxide dismutase (SOD1) is a ubiquitous enzyme responsible for scavenging superoxide radicals. Mutations in SOD1, which alter its metal binding capacity and can result in protein misfolding and aggregation, have been linked to familial amyotrophic lateral sclerosis (ALS). Cu-ATSM is an orally bioavailable, blood-brain barrier permeable complex that has traditionally been used in cellular imaging experiments to selectively label hypoxic tissue via its susceptibility to reduction by oxygen-depleted mitochondria. More recently, Cu-ATSM has been reported to improve locomotor function and survival in a transgenic ALS mouse model by delivering copper specifically to cells in the spinal cords of mice producing misfolded SOD1 proteins. Copper chaperone for SOD (CCS) is presumed to utilize the copper from Cu-ATSM to prevent misfolding of the SOD1 protein.供給者とメーカー
Henan Tianfu Chemical Co.,Ltd.
Hangzhou FandaChem Co.,Ltd.
Aladdin Scientific
YangZhou Ruihong Biotech Co., Ltd.
Sigma-Aldrich
Shanghai EFE Biological Technology Co., Ltd.
Tianjin Kailiqi Biotechnology Co., Ltd.
Shanghai Hongye Biotechnology Co. Ltd
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
MedBioPharmaceutical Technology Inc