アンピシリン-D5

プロパティ

安全情報

説明

Ampicillin-d₅ is intended for use as an internal standard for the quantification of ampicillin by GC- or LC-MS. Ampicillin is a broad-spectrum antibiotic with activity against Gram-positive and Gram-negative bacteria, including veterinary isolates of S. pseudintermedius, S. aureus, E. coli, Pasteurella, and S. canis (MIC₅₀s = 0.25, 0.5, 2, 0.12, and 0.25 μg/ml, respectively).¹ In vivo, ampicillin (80 mg/kg, i.v.) reduces cough frequency, tachypnea, dyspnea, and fever and increases survival in a baboon (P. cynocephalus) model of pneumococcal pneumonia.² Formulations containing ampicillin have been used to treat a variety of bacterial infections.