フェンベンダゾール-D3

プロパティ

安全情報

説明

Fenbendazole-d₃ is intended for use as an internal standard for the quantification of fenbendazole by GC- or LC-MS. Fenbendazole is a benzimidazole anthelmintic. It is active against Giardia in vitro (IC₅₀ = 0.3 μM). Fenbendazole (20 mg/kg) prevents infiltration of parasites into the brain in a rabbit model of E. cuniculi infection. It also activates HIF-1α and prevents oxidative stress-induced death in primary neurons in vitro.