ゲピロン
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- ¥307500 - ¥1035000
- 化学名: ゲピロン
- 英語名: Gepirone
- 別名:ゲピロン;4,4-ジメチル-1-[4-[4-(2-ピリミジニル)-1-ピペラジニル]ブチル]-2,6-ピペリジンジオン;ゲピロン;4,4-ジメチル-1-{4-[4-(ピリミジン-2-イル)ピペラジン-1-イル]ブチル}ピペリジン-2,6-ジオン
- CAS番号: 83928-76-1
- 分子式: C19H29N5O2
- 分子量: 359.47
- EINECS:
- MDL Number:MFCD00868196
4物価
選択条件:
ブランド
- 富士フイルム和光純薬株式会社(wako)
パッケージ
- 250mg
- 1g
- 生産者富士フイルム和光純薬株式会社(wako)
- 製品番号W01FLC242161
- 製品説明
- 英語製品説明4,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione
- 包装単位250mg
- 価格¥307500
- 更新しました2021-03-23
- 購入
- 生産者富士フイルム和光純薬株式会社(wako)
- 製品番号W01MAS099512
- 製品説明
- 英語製品説明4,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione
- 包装単位250mg
- 価格¥425500
- 更新しました2024-03-01
- 購入
- 生産者富士フイルム和光純薬株式会社(wako)
- 製品番号W01FLC242161
- 製品説明
- 英語製品説明4,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione
- 包装単位1g
- 価格¥764400
- 更新しました2021-03-23
- 購入
- 生産者富士フイルム和光純薬株式会社(wako)
- 製品番号W01MAS099512
- 製品説明
- 英語製品説明4,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione
- 包装単位1g
- 価格¥1035000
- 更新しました2024-03-01
- 購入
生産者 | 製品番号 | 製品説明 | 包装単位 | 価格 | 更新時間 | 購入 |
---|---|---|---|---|---|---|
富士フイルム和光純薬株式会社(wako) | W01FLC242161 | 4,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione |
250mg | ¥307500 | 2021-03-23 | 購入 |
富士フイルム和光純薬株式会社(wako) | W01MAS099512 | 4,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione |
250mg | ¥425500 | 2024-03-01 | 購入 |
富士フイルム和光純薬株式会社(wako) | W01FLC242161 | 4,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione |
1g | ¥764400 | 2021-03-23 | 購入 |
富士フイルム和光純薬株式会社(wako) | W01MAS099512 | 4,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione |
1g | ¥1035000 | 2024-03-01 | 購入 |
プロパティ
融点 :106-108°C
沸点 :562.3±60.0 °C(Predicted)
比重(密度) :1.142±0.06 g/cm3 (20 ºC 760 Torr)
貯蔵温度 :under inert gas (nitrogen or Argon) at 2-8°C
溶解性 :Chloroform (Slightly), Methanol (Slightly, Heated)
外見 :Solid
酸解離定数(Pka) :7.72±0.10(Predicted)
色 :Off-White to Pale Yellow
沸点 :562.3±60.0 °C(Predicted)
比重(密度) :1.142±0.06 g/cm3 (20 ºC 760 Torr)
貯蔵温度 :under inert gas (nitrogen or Argon) at 2-8°C
溶解性 :Chloroform (Slightly), Methanol (Slightly, Heated)
外見 :Solid
酸解離定数(Pka) :7.72±0.10(Predicted)
色 :Off-White to Pale Yellow
安全情報
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説明
Gepirone is a chemical analogue of buspirone and also acts as a partial agonist at 5-HT1A receptors. It is active in animal models predictive of anxiolytic action and also shows antidepressant activity in preclinical studies. With long-term administration, gepirone downregulates 5-HT2 receptors, which is a property common to nearly all antidepressant drugs (Stahl 1994). This dual action, suggesting both anxiolytic and antidepressant effects, is typical of many compounds acting at 5-HT1A receptors and may indicate that such compounds may be useful in the treatment of mixed anxiety and depression (Stahl, in press).Preliminary phase II clinical data have shown that gepirone is an effective anxiolytic that significantly reduces both psychic and somatic symptoms of generalized anxiety disorder. Like buspirone, gepirone does not impair memory, verbal fluency, or psychomotor performance (Harto and Branconnier 1988).
関連商品価格
- アザペロン
¥14630-266400 - ピペミド酸
¥10200-108500 - 6-HYDROXY BUSPIRONE
¥76200-581100
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