BI 6015
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2物価
選択条件:
ブランド
- 富士フイルム和光純薬株式会社(wako)
パッケージ
- 10mg
- 50mg
- 生産者富士フイルム和光純薬株式会社(wako)
- 製品番号W01TOC4641
- 製品説明
- 英語製品説明BI 6015
- 包装単位10mg
- 価格¥71000
- 更新しました2024-03-01
- 購入
- 生産者富士フイルム和光純薬株式会社(wako)
- 製品番号W01TOC4641
- 製品説明
- 英語製品説明BI 6015
- 包装単位50mg
- 価格¥291000
- 更新しました2024-03-01
- 購入
生産者 | 製品番号 | 製品説明 | 包装単位 | 価格 | 更新時間 | 購入 |
---|---|---|---|---|---|---|
富士フイルム和光純薬株式会社(wako) | W01TOC4641 | BI 6015 |
10mg | ¥71000 | 2024-03-01 | 購入 |
富士フイルム和光純薬株式会社(wako) | W01TOC4641 | BI 6015 |
50mg | ¥291000 | 2024-03-01 | 購入 |
プロパティ
沸点 :570.6±60.0 °C(Predicted)
比重(密度) :1.45±0.1 g/cm3(Predicted)
貯蔵温度 :+2C to +8C
溶解性 :Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 10 mg/ml).
外見 :Beige powder
酸解離定数(Pka) :0.88±0.10(Predicted)
色 :Tan
安定性: :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
比重(密度) :1.45±0.1 g/cm3(Predicted)
貯蔵温度 :+2C to +8C
溶解性 :Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 10 mg/ml).
外見 :Beige powder
酸解離定数(Pka) :0.88±0.10(Predicted)
色 :Tan
安定性: :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
安全情報
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説明
Hepatocyte nuclear factor 4α (HNF4α) is a nuclear receptor transcription factor that controls the expression of many genes including those involved in glucose and lipid homeostasis and maintenance of epithelial differentiation. BI6015 is a small molecule antagonist of Hepatocyte nuclear factor 4α (HNF4α) that has been shown to repress the expression of known HNF4α target genes. At concentrations up to 20 μM, BI6015 has been shown to reduce endogenous insulin gene expression by as much as 50-fold in T6PNE cells. The hepatocytes from livers of mice injected with 10 and 30 mg/kg BI6015 exhibit marked, dose-dependent fat accumulation (steatosis). Additionally, at a daily dose of 30 mg/kg, BI6015 induces apoptosis in a human hepatocellular carcinoma mouse model.関連商品価格
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供給者とメーカー
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