| | 74847-35-1 Basic information More.. |
| Product Name: | Pyronaridine | | Synonyms: | 4-[(7-CHLORO-2-METHOXY-1,5-DIHYDROBENZO[B][1,5]NAPHTHYRIDIN-10-YL)IMINO]-2,6-BIS(PYRROLIDIN-1-YLMETHYL)CYCLOHEXA-2,5-DIEN-1-ONE;Malaridine phosphate;4-(7-chloro-2-Methoxybenzo[b][1,5]naphthyridin-10-ylaMino)-2,6-bis(pyrrolidin-1-ylMethyl)phenol;Pyronaridine;4-(2-Methoxy-6-chloro-1,10-diazaanthracene-9-ylamino)-2,6-bis(pyrrolizinomethyl)phenol;4-[(7-Chloro-2-methoxybenzo[b]-1,5-naphthyridin-10-yl)amino]-2,6-bis(1-pyrrolidinylmethyl)phenol;Phenol, 4-[(7-chloro-2-methoxybenzo[b]-1,5-naphthyridin-10-yl)amino]-2,6-bis(1-pyrrolidinylmethyl)-;4-[(7-chloro-2-methoxy-1,5-dihydrobenzo[b][1,5]naphthyridin-... | | CAS: | 74847-35-1 | | MF: | C29H32ClN5O2 | | MW: | 518.05 | | EINECS: | 1533716-785-6 | | Mol File: | 74847-35-1.mol |  |
Use
Pyronaridine is active against the asexual erythrocytic stage of
P. falciparum with little or no activity against gametocytes or the
hepatic stage. In-vitro blood schizonticide activities are in the
range of 0.001–0.03 mg/L, showing a moderate correlation to
chloroquine resistance. However, this correlation varies between
studies and does not seem to be clinically significant. It is also
active against P. vivax, P. ovale and P. malariae. Antagonistic
interactions with artemisinins were reported in vitro, but synergy
with artesunate has been observed in rodent models.
- Pyronaridine
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- US $0.00-0.00 / g
- 2024-04-07
- CAS:74847-35-1
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 20 tons
- Malaridine
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- US $0.00 / mg
- 2024-04-02
- CAS:74847-35-1
- Min. Order: 10mg
- Purity: 0.98
- Supply Ability: 10g
- Malaridine
-
- US $0.00 / mg
- 2024-03-29
- CAS:74847-35-1
- Min. Order: 10mg
- Purity: 0.98
- Supply Ability: 10g
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74847-35-1
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