Crotalidae Polyvalent immune Fab

Use

Crotalidae Polyvalent Immune Fab (ovine) was launched as CroFab in the US for the treatment of North American crotalid snake envenomation. It is the second antivenom to be commercialized over fifty years after Antivenin (Crotalidae) Polyvalent (equine) from Wyeth Labs. CroFab? is prepared by purification of Fab immunoglobulin fragments obtained from the blood of healthy sheep flocks immunized with one of the following North American snake venoms: Crotalus atrox (Western Diamondback rattlesnake), Crotalus adamanteus (Eastern Diamondback rattlesnake), Crotalus scutulatus (Mojave rattlesnake), and Agkistrodon piscivorus (Cottonmouth or Water Moccasin).