| | 140462-76-6 Basic information More.. |
| Product Name: | Olopatadine hydrochloride | | Synonyms: | OLOPATADINE HYDROCHLORIDE;OLOPATDINEHYDROCHLORIDE;OLOPATADINE HYDROCHLORIDE AND THE INTERMEDIATES;(Z)-11-[3-(Dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid hydrochloride;Olopatadine Hydrochloride (150 mg);Olopatadin HCL (DFM Gr)INN;(11Z)-11-[3-(Dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid hydrochloride;AL-4943A | | CAS: | 140462-76-6 | | MF: | C21H24ClNO3 | | MW: | 373.88 | | EINECS: | 604-185-4 | | Mol File: | 140462-76-6.mol |  |
Use
Olopatadine hydrochloride is a potent, selective antagonist of the H1 histamine receptor (Ki = 16-41.1 nM), with much lower affinities for the H2 and H3 receptors (Ki = 43.4 and 172 μM, respectively). It blocks histamine-induced phosphoinositide turnover in isolated cells (IC50 = 9.5-39.9 nM) and prevents passive cutaneous anaphylaxis in rats (ED50 = 49 μg/kg) and anaphylactic bronchoconstriction in guinea pigs (ID50 = 30 μg/kg). Olopatadine is effective in treating allergic rhinitis and conjunctivitis. It also suppresses itch in patients with well-controlled chronic urticaria. In humans, this antihistamine does not cause cognitive or psychomotor impairment at therapeutic doses.[Cayman Chemical]
- Olopatadine Hydrochloride
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- US $0.00-0.00 / kg
- 2025-01-13
- CAS:140462-76-6
- Min. Order: 5kg
- Purity: 98%-102%
- Supply Ability: 200kg
- Olopatadine Hydrochloride
-
- US $0.00 / g
- 2025-01-13
- CAS:140462-76-6
- Min. Order: 1g
- Purity: More Than 99%
- Supply Ability: 50kg/Month
- Olopatadine Hydrochloride.
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- US $0.00 / g
- 2025-01-13
- CAS:140462-76-6
- Min. Order: 1g
- Purity: More Than 99%
- Supply Ability: 100kg/Month
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140462-76-6
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