| | 179113-91-8 Basic information More.. |
| Product Name: | NAGLY | | Synonyms: | N-ARACHIDONOYL GLYCINE;N-ARACHIDONYL GLYCINE;NAGLY;N-(1-OXO-5Z,8Z,11Z,14Z-EICOSATETRAENYL)GLYCINE;ARACHIDONOYL GLYCINE;N-Arachidonoyl glycine (solution in ethanol);Glycine, N-[(5Z,8Z,11Z,14Z)-1-oxo-5,8,11,14-eicosatetraen-1-yl]-;Arachidonyl Glycine | | CAS: | 179113-91-8 | | MF: | C22H35NO3 | | MW: | 361.52 | | EINECS: | | | Mol File: | 179113-91-8.mol |  |
Use
Arachidonoyl glycine (N-arachidonyl glycine; NAGly) has been isolated from cell cultures treated with arachidonoyl ethanolamide (AEA; anandamide), from extracts of mammalian brain, and has also been synthesized as an analog of AEA for structure/activity testing. NAGly may be produced endogenously via oxidation of AEA, or by transacylation of arachidonoyl CoA. NAGly is reported to have analgesic activities in whole animal experiments. Since it seems to be a very poor ligand for the CB1 receptor, these effects are probably mediated via other signaling pathways.[Cayman Chemical]
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179113-91-8
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