78111-17-8 Basic information More..
Product Name:OKADAIC ACID
Synonyms:1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoicacid, a,5-dihydroxy-a,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(;Okadaic acid 35-Demethyl-DTX 1 NSC 677083 35-Demethyldinophysistoxin 1;OA;OKADAIC ACID, PROROCENTRUM CONCAVUM;35-Demethyldinophysistoxin 1;35-Demethyl-DTX 1;NSC 677083;9,10-DEEPITHIO-9,10-DIDEHYDROACANTHIFOLICIN
CAS:78111-17-8
MF:C44H68O13
MW:805
EINECS:616-589-8
Mol File:78111-17-8.mol
78111-17-8

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Okadaic acid is a widely distributed marine toxin produced by several phytoplanktonic species and responsible for diarrheic shellfish poisoning in humans. At the molecular level, Okadaic acid is a pot ent and specific inhibitor of various types of serine/threonine protein phosphatases. Due to this enzymatic inhibition, Okadaic acid was reported to induce numerous alterations in relevant cellular ph ysiological processes, including metabolic pathways such as glucose uptake, lipolysis and glycolysis, heme metabolism and glycogen and protein synthesis.

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