| | 700874-72-2 Basic information More.. |
| Product Name: | LY 2157299 | | Synonyms: | LY 2157299;4-[5,6-Dihydro-2-(6-methyl-2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-6-quinolinecarboxamide;6-QuinolinecarboxaMide, 4-[5,6-dihydro-2-(6-Methyl-2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-;4-[2-(6-Methyl-2-pyridinyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-6-quinolinecarboxaMideorLY2157299;GALUNISERTIB;Galunisertib,LY2157299;4-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-6-carboxamide;4-[5,6-Dihydro-2-(6-methyl-2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-6-quinolinecarboxamide LY 2157299 | | CAS: | 700874-72-2 | | MF: | C22H19N5O | | MW: | 369.42 | | EINECS: | | | Mol File: | 700874-72-2.mol |  |
Use
LY2157299 is a small molecule inhibitor of the TGF-β receptor type 1 kinase (IC50 = 56 nM). It has been used to study the role of TGF-β signaling in chemotherapy-induced expansion of cancer stem-like cells in triple negative breast cancer cell lines and xenografts. LY2157299 has also been shown to inhibit the migration and tumor growth of hepatocellular carcinoma cell lines by disrupting Smad-2 phosphorylation.[Cayman Chemical]
- Galunisertib
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- US $40.00-81.00 / mg
- 2024-11-07
- CAS:700874-72-2
- Min. Order:
- Purity: 99.98%
- Supply Ability: 10g
- Galunisertib
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- US $0.00 / g
- 2024-11-06
- CAS:700874-72-2
- Min. Order: 1g
- Purity: More Than 99%
- Supply Ability: 100kg/Month
- LY 2157299
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- US $2.00 / kg
- 2019-07-06
- CAS:700874-72-2
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 100kg
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700874-72-2
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