41307-63-5 Basic information More..
Product Name:Resorcinolnaphthalein
Synonyms:Resorcinolnaphthalein;FTUOFHGOGJGQAB-UHFFFAOYSA-N;fibrosis,ACE2,hypertension,renal,perivascular,Resorcinolnaphthalein,reversal,inhibit,myocardial,Inhibitor,Angiotensin-converting Enzyme (ACE);Spiro[1H,3H-naphtho[1,8-cd]pyran-1,9'-[9H]xanthen]-3-one, 3',6'-dihydroxy-
CAS:41307-63-5
MF:C24H14O5
MW:382.36
EINECS:
Mol File:41307-63-5.mol
41307-63-5

Use

Angiotensin-converting enzyme 2 (ACE2) is an enzyme that is cardioprotective and renoprotective. Resorcinolnaphthalein increases the activity of ACE2 in vitro (EC50 = 19.5 μM). Activation of ACE2 in rats produces a decrease in blood pressure and improvement in cardiac function. In spontaneously hypertensive rats it produces a reversal of myocardial, perivascular, and renal fibrosis.[Cayman Chemical]

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