2-TrifluoroMethyl-2'-Methoxychalcone
| | 1309371-03-6 Basic information More.. |
| Product Name: | 2-TrifluoroMethyl-2'-Methoxychalcone | | Synonyms: | 2-TrifluoroMethyl-2'-Methoxychalcone;2-Propen-1-one, 1-(2-methoxyphenyl)-3-[2-(trifluoromethyl)phenyl]-, (2E)-;(2E)-1-(2-Methoxyphenyl)-3-[2-(trifluoromethyl)phenyl]-2-propen-1-one;2-Trifluoromethyl-2'-methoxychalcone | | CAS: | 1309371-03-6 | | MF: | C17H13F3O2 | | MW: | 306.28 | | EINECS: | | | Mol File: | 1309371-03-6.mol |  |
Use
2-Trifluoromethyl-2'-methoxychalcone is a novel chalcone derivative as potent Nrf2 activators in mice and human lung epithelial cells.
2-Trifluoromethyl-2'-methoxychalcone is a potent activator of Nrf2, both, in vitro and in mice. 4 Human bronchial epithelial cells treated with 10 μM 2-trifluoromethyl-2'-methoxychalcone showed a marked increase in the expression of the Nrf2-regulated antioxidant genes, GCLM and NQO1.
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1309371-03-6
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